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Gingival Recession clinical trials

View clinical trials related to Gingival Recession.

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NCT ID: NCT04584931 Not yet recruiting - Gingival Recession Clinical Trials

Treatment of Gingival Recession Using Gingival Composite Restoration Versus Coronally Advanced Flap

Start date: October 1, 2021
Phase: N/A
Study type: Interventional

Treatment of gingival recession requires favourable anatomical conditions and the use of invasive surgical approaches. Hence, these procedures are not always indicated in all cases and can cause great pain and morbidity. Coloured composite restorations that mimic the lost gingival tissues can provide a non-invasive and simple solution regardless of the recession soft and hard-tissue conditions.

NCT ID: NCT04561947 Completed - Gingival Recession Clinical Trials

Treatment of Gingival Recessions With Connective Tissue or Concentrated Growth Factor Membrane Using Tunnel Technique

Start date: October 1, 2017
Phase: N/A
Study type: Interventional

This randomized controlled clinical study aimed to evaluate the success of the combination of tunnel technique and concentrated growth factor membrane for root coverage in treating multiple gingival recessions and compare with the gold standard connective tissue graft.

NCT ID: NCT04514055 Completed - Recession, Gingival Clinical Trials

Connective Tissue Graft Wall Technique in Management of Cairo's RT2 and RT3 With Intra-bony Defects

Start date: October 1, 2020
Phase: N/A
Study type: Interventional

Recession presents a day to day challenge due to the high esthetic demand of the patients. The prevalence, extent, and severity of recession associated with intra-bony defects due to periodontitis increases with age rendering the success of the root coverage procedures questionable due to loss of interdental papillary support. . Therefore, connective tissue graft wall technique in cases of Cairo's RT2 and RT3 gingival recession associated with intra bony defects seems promising with regard to recession depth reduction and radiographic bone fill.

NCT ID: NCT04513041 Recruiting - Gingival Recession Clinical Trials

Pinhole Versus Tunnel for Soft Tissue Recession

Start date: June 25, 2020
Phase: N/A
Study type: Interventional

This is an assessor-blinded split-mouth randomized clinical study to compare root coverage and gingival tissue thickness following two different surgical procedures for non-autologous grafting: the pinhole surgical technique (PST) and tunnel technique.

NCT ID: NCT04487652 Completed - Gingival Recession Clinical Trials

Ubiquinone (Coenzyme Q10) Application After Gingival Recession Coverage

Start date: September 1, 2020
Phase: N/A
Study type: Interventional

This randomised double blinded clinical trial has the aim to assess the effect of ubiquinone (Coenzyme Q10) on early wound healing following gingival recession coverage. Coenzyme Q10 (CoQ10) is a critical intermediate of the mitochondrial electron transport chain for the synthesis of adenosine triphosphate. The biological importance of CoQ10 is related to antioxidant activity, which can scavenge free radicals as well as restore the antioxidant defence system. Both in vitro and animal studies have suggested that CoQ10 acts as anti-inflammatory agent reducing the inflammatory response by inhibiting the translocation of nuclear factor kappa beta into the nucleus. Gingival recessions particularly in the esthetic area have become a common indication for treatment. The use of subepithelial palatal connective tissue graft (SCTG) in conjunction with either a coronally advanced flap (CAF) or a coronally advanced tunnel are well established techniques for both the treatment of single and multiple gingival recessions. Interestingly, despite the fact that CoQ10 is widely investigated, virtually no information exists on its effects upon early wound healing of oral tissues. Therefore, the aim of this study is to investigate the effect of CoQ10 on wound healing after gingival recession surgery.

NCT ID: NCT04462237 Completed - Gingival Recession Clinical Trials

Recombinant Human Platelet-derived Growth Factor in Combination With Collagen Matrix

Start date: September 9, 2020
Phase: N/A
Study type: Interventional

The present randomized clinical trial is aimed at evaluating the efficacy of recombinant human platelet-derived growth factor in combination with collagen matrix for the treatment of multiple adjacent gingival recessions

NCT ID: NCT04434794 Completed - Gingival Recession Clinical Trials

Treatment of Gingival Recession Using Mesenchymal Stem Cells

Start date: January 1, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

Treatment of patients with gingival recession by injection of autologous adipose-derived mesenchymal stem cells mixed with collagen gel

NCT ID: NCT04375618 Recruiting - Periodontitis Clinical Trials

RhEGF Incorporated in An Absorbable Collagen Membrane for The Management Of Gingival Recession Defects

Start date: October 1, 2019
Phase: Phase 1
Study type: Interventional

A sulcular incision will be made through each recession area and the tissues will be gradually undermined including the base of the interdental papilla. At the recession sites rhEGF incorporated absorbable collagen membrane will be gradually manipulated into the pouch through the tunnel till it covers the recession sites and will be stabilized with sutures.

NCT ID: NCT04361630 Completed - Periodontitis Clinical Trials

Recombinant Human Fibroblast Growth Factor-2 (rhFGF-2) In Gingival Recession Defects

Start date: May 1, 2019
Phase: Early Phase 1
Study type: Interventional

This study was a single-arm trial to obtain preliminary data on the efficacy of collagen membranes impregnated with recombinant human fibroblast growth factor (rhFGF-2) in the treatment of Miller's class I and class II gingival recessions.

NCT ID: NCT04356391 Completed - Clinical trials for Periodontal Diseases

Pinhole Surgical Technique Compared to Connective Tissue Graft in Treatment of Gingival Recession

Start date: January 24, 2018
Phase: N/A
Study type: Interventional

This study compares the efficacy of root coverage achieved by the Pinhole Surgical Technique (PST) technique and the Connective Tissue Graft (CTG) technique in the treatment of Miller class I and II gingival recession defects. All patients will receive PST in one quadrant and CTG in another quadrant. The hypothesis being tested is: Pinhole Surgical Technique outcomes are not inferior to those of the Connective Tissue Graft surgical technique.