Clinical Trials Logo

Clinical Trial Summary

In this study, we aimed to determine the knowledge levels and approaches of anesthesiologists working in our clinic about postoperative residual curarization(PORC) in elderly patients with a questionnaire. In addition, we aimed to determine the incidence of PORC and factors associated with PORC in the recovery unit in elderly patients over 65 years of age who underwent surgery under general anesthesia using muscle relaxants with a prospective observational study.


Clinical Trial Description

Postoperative residual curarization (PORC) after general anesthesia is an important complication that can cause adverse patient outcomes, including symptoms of airway obstruction, hypoxia, respiratory distress, muscle weakness, and dyspnea in the early and late stages. Anticholinesterase agents are commonly used to reverse neuromuscular blockade. Even with the use of anticholinesterase, severe PORC can be seen. The use of anticholinesterases in elderly patients is controversial due to the high side-effect profile. Sugammadex, which has been widely used with its approval by the United States Food and Drug Administration in 2015, is a reverse agent that acts through a different mechanism than traditional anticholinesterase agents (it is a cyclodextrin molecule that encapsulates steroid neuromuscular blockers). Compared to neostigmine, sugammadex reverses neuromuscular blockade faster and more reliably. In this study, we aimed to determine the knowledge levels and approaches of anesthesiologists working in our clinic about postoperative residual curarization(PORC) in elderly patients with a questionnaire. In addition, we aimed to determine the incidence of PORC and factors associated with PORC in the recovery unit in elderly patients over 65 years of age who underwent surgery under general anesthesia using muscle relaxants with a prospective observational study. The first phase of the study is a prospective observational study. Elderly patients (>65) who are scheduled to undergo elective surgery under general anesthesia and require intubation using muscle relaxants will be screened for PORC using Train of four monitor in the recovery unit. In the second phase of the study, an online questionnaire with 15 questions will determine the knowledge and attitudes of anesthesiologists working in our clinic on the use of muscle relaxants and reversing agents in elderly patients, the use of neuromuscular monitoring and PORC. ;


Study Design


Related Conditions & MeSH terms

  • Delayed Emergence from Anesthesia
  • Geriatrics
  • Postoperative Residual Curarization

NCT number NCT05051371
Study type Observational
Source Ankara City Hospital Bilkent
Contact Aysun Postaci
Phone +90 5323520383
Email aysunposta@yahoo.com
Status Recruiting
Phase
Start date August 15, 2021
Completion date December 2021

See also
  Status Clinical Trial Phase
Completed NCT02558907 - Comparison of MMSE (Mini-Mental State Examination) and MoCA (Montreal Cognitive Assessment) in Cognitive Assessment in Geriatric Oncology N/A
Completed NCT05197127 - Efficacy of Samsung GEMS-H Device Training in Older Adults N/A
Not yet recruiting NCT06267833 - The Effect of Trunk and Upper Extremity Exercises Added to the Otago Exercise Program N/A
Completed NCT03188211 - E-learning to Improve Oral Anticoagulant Use in Hospitalized Older People With AF N/A
Completed NCT04577092 - Dual Task Training for Balance in Older Adults N/A
Recruiting NCT05605392 - Live Better at Home, Navarra ( VMNav ) N/A
Completed NCT04069962 - Effectiveness of CGA on QoL in Older Patients With Cancer Receiving Systemic Therapy N/A
Recruiting NCT02377908 - European Postgraduate Training in Geriatric Medicine N/A
Completed NCT04171752 - Elafibranor Pharmacokinetic Parameters in Elderly Healthy Volunteers Phase 1
Not yet recruiting NCT05567965 - Live Better at Home in Catalonia N/A
Withdrawn NCT04010136 - Identification of Elderly Patients in Need of Palliative Care by Family Physicians N/A
Not yet recruiting NCT06300281 - Comparison of Neuromuscular and Aquatic Exercise Programs on Fall Risk and Physical Function in Geriatrics N/A
Completed NCT05400850 - YOGA Asanas and Myofascial Chain Activity in Elderly Individuals N/A
Completed NCT02118259 - Impact of Multidisciplinary Review of Drug Prescriptions on Patient Safety in a Residence for Dependent Elderly N/A
Completed NCT06209944 - Charlson Comorbidity Index and Outcome of Cardiopulmonary Resuscitation in Geriatric Patients in Hong Kong
Completed NCT06189430 - Effect of Vinyasa Yoga on Frailty and Anthropometric Measurements in Elderly Individuals N/A
Withdrawn NCT02398851 - TacTIC- Trans-disciplinary Chronic Disease Continuity of Care Model N/A
Completed NCT04935541 - Dexmedetomidine vs. Remifentanil Undergoing Cataract Surgery in Geriatrics N/A
Recruiting NCT02604563 - Aging, Geriatric Syndromes and Clonal Hematopoiesis
Recruiting NCT05939531 - Multi-domain Intervention Program for Post-stroke Bone Health in Older Adults (BOUNCE) N/A