GERD Clinical Trial
Official title:
A Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Two Period Crossover, Single Dose-Finding Study to Assess the Efficacy and Safety of Controlled Release XP19986 in Patients With Gastroesophageal Reflux Disease
The purpose of the study is to evaluate the efficacy and safety of arbaclofen placarbil (XP19986) compared to placebo in patients with gastroesophageal reflux disease.
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT06084572 -
Prospective Evaluation of pH-impedance Tracings According to the Wingate Consensus, and Influence on GERD Classification According to the Lyon Consensus
|
||
| Completed |
NCT03568825 -
Response Surface Pathway Design With Two Interventional- and One Response Variable in Estimating Minimum Efficacy Dose
|
N/A | |
| Recruiting |
NCT04703374 -
A Study to Compare PK, PD and Safety of CKD-382 in Healthy Subjects
|
Phase 1 | |
| Completed |
NCT04120025 -
Effectiveness of Diaphragmatic Breathing on Reflux Symptoms in Outpatients
|
N/A | |
| Withdrawn |
NCT04771247 -
Endoscopic Cardiac Band Ligation for the Management of Refractory GERD After Laparoscopic Sleeve Gastrectomy
|
N/A | |
| Completed |
NCT02575287 -
Minimal Injuries From Esophagus Detected by Optical Enhancement System™ Associated to Optical Magnification HD Scopes
|
N/A | |
| Completed |
NCT01710800 -
Twenty-Four Hour Combined Multi-Channel Impedance and pH Ambulatory Monitoring: Impedance Reflux Episodes of Patients On and Off Proton Pump Inhibitor Therapy
|
N/A | |
| Completed |
NCT00287339 -
The Utility of Nexium in Chronic Cough and Reflux Disease
|
Phase 4 | |
| Completed |
NCT00287391 -
Sleep Disorders and Gastroesophageal Reflux Disease (GERD)
|
Phase 4 | |
| Completed |
NCT00629564 -
An Open, Randomized, Two Way Crossover Study Comparing the Effect of 20mg Esomeprazole Administered Orally and Intravenously as a 15 Minute Infusion on Basal and Pentagastrin-Stimulated Acid Output in Subjects With Symptoms of Gastroesophageal Reflux Disease (GERD)
|
Phase 4 | |
| Completed |
NCT04243668 -
ANTI REFLUX MUCOSAL ABLATION THERAPHY (ARMA)
|
N/A | |
| Completed |
NCT03558477 -
PK/PD Clinical Trial of YYD601 in Healthy Adult Male
|
Phase 1 | |
| Recruiting |
NCT05042063 -
Acoustic Cough Monitoring for the Management of Patients With Known Respiratory Disease
|
||
| Completed |
NCT05069493 -
Long-term Follow-up After Hiatal Hernia Repair by Tension-free Mesh Closure or Simple Suturing
|
||
| Completed |
NCT03238534 -
Efficacy and Safety Evaluation of Neobianacid® in GERD and EPS
|
Phase 4 | |
| Recruiting |
NCT05974722 -
Mesh Vs Pledgets for Repair of Paraesophageal Hernia
|
N/A | |
| Recruiting |
NCT05781347 -
Stretta Versus Conservative Treatment in Obese and Non-obese
|
N/A | |
| Completed |
NCT06141577 -
A Study to Compare Pharmacokinetics, Pharmacodynamics and Safety of UI059 and UIC202201 in Healthy Subjects
|
Phase 1 | |
| Recruiting |
NCT05108038 -
A Study to Evaluate the PK, PD and Safety of CKD-382 in Healthy Subjects
|
Phase 1 | |
| Recruiting |
NCT02587910 -
Melanole, a Dietary Supplement, for the Treatment of Gastroesophageal Reflux Disease
|
Phase 2/Phase 3 |