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Clinical Trial Summary

This trial is an open-label, multicenter, Phase 0 trial that will enroll up to 20 participants with recurrent high-grade glioma with FGFR1 K656E or FGFR3 K650E mutation or FGFR3-TACC3 translocation which are scheduled for resection. In the lead-in cohort, a total of 20 participants will be enrolled into the proposed phase 0 clinical trial. Participants will be administered infigratinib prior to surgical resection of their tumor.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04424966
Study type Interventional
Source St. Joseph's Hospital and Medical Center, Phoenix
Contact
Status Terminated
Phase Early Phase 1
Start date July 21, 2020
Completion date April 27, 2023

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