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Gastritis clinical trials

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NCT ID: NCT02037776 Completed - Clinical trials for Functional Dyspepsia

The Efficacy and Safety Study of Rikkunshito in Patients With Functional Dyspepsia

Start date: April 3, 2014
Phase: Phase 4
Study type: Interventional

The purpose of this study is to assess the efficacy and safety of Rikkunshito compared to placebo in Japanese subjects with Functional Dyspepsia (FD).

NCT ID: NCT01828645 Completed - Peptic Ulcer Clinical Trials

Residual Gastric Volume After the Ingestion of a Beverage Containing Carbohydrates Plus Whey Protein

Start date: February 2013
Phase: Phase 2/Phase 3
Study type: Interventional

Carbohydrate enriched-drinks has been used as preoperative treatment up to two hours before anesthesia. These drinks are safe and are not associated to bronchial aspiration during anesthesia. The addition of protein may be beneficial for metabolic preconditioning but there is a few data in literature testing these drinks for safety. The aim of the study will be to investigate the residual gastric volume (RGV) measured during the gastroscopy with abbreviation of fast to 2h with a carbohydrate plus whey protein enriched-drink.

NCT ID: NCT01817556 Completed - Chronic Gastritis Clinical Trials

A Study to Evaluate the Efficacy and of Stillen Tab. and to Demonstrate the Non-inferiority of Stillen Tab.

Start date: October 2012
Phase: Phase 4
Study type: Interventional

This is a multicenter, active-controlled, randomized, double-blinded, paralleled group clinical study to evaluate the efficacy of 4-week treatment with Stillen tab. in patients with acute or chronic gastritis. Subject will receive Stillen tab or Mucosta tab., three times a day for four weeks.

NCT ID: NCT01813994 Completed - Clinical trials for Early Gastric Cancer or Gastric Adenoma

Role of Statin on the Gastric Inflammation in Patients at High Risk of Gastric Cancer

Start date: November 2014
Phase: N/A
Study type: Interventional

Statins are commonly used as cholesterol-lowering medications and have shown effectiveness in the primary and secondary prevention of heart attack and stroke. In addition, several recent studies of human cancer cell lines and animal tumor models indicate that statins may have chemopreventive properties through the arresting of cell-cycle progression. The chemopreventive effect of statins was demonstrated in some kind of human tumors including colorectal cancer. In addition, recent one large epidemiologic study showed that statins decreased risk of gastric cancer. On the other hands, it has been well known that Helicobacter pylori infection induces gastric atrophy and intestinal metaplasia, which are premalignant lesions of gastric cancer. Progression of these premalignant lesions could be limited by H. pylori eradication. In addition, a recent double blind randomization study revealed that simvastatin as adjuvant to standard therapy improves significantly the H. pylori eradication rate. Therefore, investigators conjecture that statins may have an adjuvant role for inhibition of gastric carcinogenesis. investigators aim to evaluate the role of statins in gastric carcinogenesis by observing the changes of gastric inflammation under statins.

NCT ID: NCT01762397 Completed - Gastritis Clinical Trials

A Clinical Trial to Investigate the Safety, Tolerability, Pharmacokinetics, and Food Effect of PMK-S005 After Oral Administration in Healthy Male Volunteers

Start date: December 2012
Phase: Phase 1
Study type: Interventional

The Purpose of a randomized, double-blind, placebo-controlled, single-dose, dose-escalation clinical trial is to explore investigate the safety, tolerability, pharmacokinetics, and food effect of PMK-S005 after oral administration in healthy male volunteers.

NCT ID: NCT01689701 Completed - Erosive Gastritis Clinical Trials

Efficacy and Safety of Hizikia Fusiformis Extract in Subjects Showing Erosive Gastritis

Start date: August 2011
Phase: N/A
Study type: Interventional

The investigators performed a double-blind parallel study in a group of Subjects Showing Erosive Gastritis who were given Hizikia Fusiformis Extract over a period of 4 weeks. Endoscopic observations were performed before and 4 weeks after the treatment, and the cure and improvement rates were investigated.

NCT ID: NCT01671670 Completed - Clinical trials for Functional Dyspepsia

Acupuncture for Patients With Function Dyspepsia

Start date: September 2012
Phase: Phase 2/Phase 3
Study type: Interventional

Hypothesis: Acupuncture is efficacious and safe for patients with functional dyspepsia Design: - A single blind randomized controlled trial - 200 participants will be included - Two arms: acupuncture and sham acupuncture group

NCT ID: NCT01643083 Completed - Clinical trials for Functional Dyspepsia

Rifaximin for Functional Dyspepsia

Start date: January 2013
Phase: Phase 2/Phase 3
Study type: Interventional

Functional dyspepsia is a very common medical condition, which occurs in up to 30% of people in the community. However, results of current pharmacological treatment on functional dyspepsia are unsatisfactory. Rifaximin is a minimally absorbed antibiotic that has been used in treatment of non-constipated irritable bowel syndrome (IBS). In particular, bloating and abdominal pain was improved by rifaximin treatment in this group of IBS patients. Whilst there is considerable overlap in symptoms of functional dyspepsia and IBS, the investigators test whether rifaximin is also effective in curing post-prandial distress symptoms related to dyspepsia.

NCT ID: NCT01591174 Completed - Clinical trials for Functional Dyspepsia

Ghrelin and Gastric Emptying in Children With Functional Dyspepsia

GHR
Start date: May 2012
Phase:
Study type: Observational

The purpose of this research is to see if there are differences between children who have FD and children without FD in the ability of the stomach to empty food and/or in ghrelin hormone levels before and after eating. Chronic abdominal pain is the most common persistent pain condition in children and adolescents. One of the most often diagnosed types of abdominal pain is functional dyspepsia (FD). FD is abdominal pain or discomfort (e.g., nausea, bloating) in the upper abdomen that does not get better by having a bowel movement. One possible explanation for having FD is a delay in the emptying of food from the stomach, or delayed gastric (stomach) emptying. Failing to empty the stomach quickly enough may result in the feeling of being full and cause symptoms of bloating, nausea, vomiting and pain. Further, hormonal changes occur before, during, or after eating food that appear to impact stomach emptying. One of the hormones that changes with meals is called ghrelin. The relationship between ghrelin and stomach emptying needs to be explored more in children with FD. Better understanding of what causes FD symptoms may help us to improve treatment for this condition.

NCT ID: NCT01578811 Completed - Erosive Gastritis Clinical Trials

Study to Assess the Efficacy and Safety of SK-MS10 in Subjects With Acute and Chronic Gastritis

Start date: August 2011
Phase: Phase 2
Study type: Interventional

The purpose of this study is to Assess the Efficacy and Safety of SK-MS10 in subjects With acute and chronic gastritis.