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Fractures, Bone clinical trials

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NCT ID: NCT02749409 Terminated - Rib Fractures Clinical Trials

Early Parecoxib Usage to Decreases Narcotic Requirement and Length of Stay After Traumatic Rib Fracture

Start date: August 8, 2016
Phase: Phase 3
Study type: Interventional

Patients diagnosed traumatic rib fracture and need admission will be included. Patients will be divided two groups.The experimental group will be given parecoxib after visiting emergency department. The control group will be given Narcotic agent such as morphine for pain control. The outcome such as numerical rating scale (NRS) and hospital length of stay will be recorded.

NCT ID: NCT02744352 Terminated - Clinical trials for Distal Radius Fracture

Single Shot vs Catheter Infraclavicular Brachial Plexus Block After Distal Radius Fracture Repair

Start date: October 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to compare infraclavicular brachial plexus shot single shot block to continuous catheter nerve block done in adult patients who have under gone surgery to repair distal radius fractures. Visual analogue scores, opioid consumption, quality of recovery and quality of sleep up to 72 hours post operatively will be used for comparison.

NCT ID: NCT02689388 Terminated - Delirium Clinical Trials

Evaluating the Addition of Regional Analgesia to Reduce Postoperative Delirium in Patients Having Hip Fracture Surgery.

RASAPOD
Start date: August 28, 2016
Phase: N/A
Study type: Interventional

Post operative delirium is common after hip fracture surgery and is associated with increased length of hospital stay, delayed recovery and increased mortality. Postoperative delirium can also decrease a patient's quality of life and increase treatment costs. Anesthesia and pain relief (analgesia) treatments may also influence the incidence of delirium, but more research is needed into which techniques are effective in improving patient outcomes, care and decreasing costs. This pilot study compares the addition of regional analgesia as part of general anesthesia to determine the incidence of delirium following hip surgery. This is a collaborative study involving anesthesia, orthopedic surgery and geriatrics in the improvement of patient care.

NCT ID: NCT02679560 Terminated - Femoral Fractures Clinical Trials

Effects of Liposomal Bupivacaine for Acute Pain in Hip and Femur Fractures

Start date: October 1, 2017
Phase: Phase 2
Study type: Interventional

This is an investigator-initiated, single-center, randomized, patient blinded, controlled trial. The purpose of this study is to compare the effect of a fascia iliaca compartment block (FICB) using 0.2% ropivacaine vs. liposomal bupivacaine in patients with femur and/or hip fractures admitted to the University of California Davis Medical Center (UCDMC). The primary endpoint will be the total opioid requirements during the 96 hour randomization period with secondary endpoints including total daily opioid requirements for days 1-4, duration of effect and objective pain scores using the numeric rating scale (NRS) during their hospital stay.

NCT ID: NCT02679066 Terminated - Clinical trials for Distal Radius Fracture

Short Forearm Casting Versus Below-elbow Splinting for Acute Immobilization of Distal Radius Fractures

Start date: January 2014
Phase: N/A
Study type: Interventional

There is no consensus regarding the need to immobilize the elbow in immediate immobilization of closed distal radius fractures post-reduction. Decreased functionality of the upper extremity is a notable morbidity associated with below-elbow splinting of distal radius fractures post-reduction. Few studies have provided evidence comparing sugar tong splinting versus short-arm casting as methods of immediate post-reduction immobilization. The study will randomize patients with close distal radius fractures to short forearm casting versus sugar tong splinting with close follow up including radiographic and clinical evaluation. This will provide guidance regarding the need for short forearm cast immobilization versus sugar tong splinting in early maintenance of reduction of closed distal radius fractures, as well as functional effects of sugar tong splinting versus short forearm casting.

NCT ID: NCT02605096 Terminated - Scaphoid Fracture Clinical Trials

Pilot Study to Test the Feasibility of the Use of MRI in Suspected Scaphoid Fractures

Start date: November 1, 2015
Phase: Phase 3
Study type: Interventional

This pilot study aims to test the feasibility and work flows associated with using MRI as the initial imaging modality in the investigation of patients presenting with suspected scaphoid fracture. This pilot will be used to inform the design of a study that will aim to evaluate whether the proposed intervention is likely to generate cost-savings whilst improving or maintaining overall patient quality of life and satisfaction.

NCT ID: NCT02597972 Terminated - Clinical trials for Closed Fracture Proximal Humerus, Four Part

Reverse Total Shoulder Arthroplasty Versus Open Reduction Internal Fixation of 3&4 Part Proximal Humerus Fractures

Start date: September 2015
Phase: N/A
Study type: Interventional

Will patients who suffer complex humerus fractures have better functional outcomes and less implant failure with shoulder replacement (reverse total shoulder arthroplasty, RTSA) compared to shoulder repair (open reduction and internal fixation, ORIF)?

NCT ID: NCT02564133 Terminated - Hip Fractures Clinical Trials

Hip Fracture and Patent Foramen Ovale

COL-FOP
Start date: June 2013
Phase: N/A
Study type: Interventional

Ereth et al. showed in 1992, using transesophageal echocardiography, that the implantation of a hip prosthesis may be complicated by intracardiac embolization of various origin. A patent foramen ovale exists in approximately one fifth of the population; it facilitates the passage of embolus from the right heart to the left one and then especially to the coronary vessels and to the brain. The hypothesis supported in this research is that the prevalence of postoperative complications, especially neurological ones, is increased after surgery for hip fracture when patients have a patent foramen ovale.

NCT ID: NCT02520297 Terminated - Pain Clinical Trials

A Pilot Study of TRV130 for the Treatment of Fracture Pain

Start date: October 20, 2015
Phase: Phase 2
Study type: Interventional

The primary objective is to evaluate the analgesic efficacy of TRV130 for moderate to severe acute pain in patients presenting to the emergency department (ED) with a suspected/known, unilateral, closed long bone fracture.

NCT ID: NCT02489825 Terminated - Osteoporosis Clinical Trials

Study About the Effect of Preventive Adjacent Level Cement Augmentation After Osteoporotic Vertebral Compression Fractures

Start date: January 2015
Phase: Phase 4
Study type: Interventional

Vertebroplasty itself is challenged regarding its clinical efficacy. While two randomized controlled trials (RCTs) with substantial methodological problems have led to an intense discussion another RCT with larger case numbers, more representative inclusion criteria and a more consistent and sound methodology has revealed results that mirror the investigators' own clinical experience. In their daily practice, the investigators have further advanced their treatment concept and routinely apply prophylactic augmentations with VP using an algorithm. Biomechanical studies support their approach, but clinical studies are rare so far. Prophylactic augmentation with balloon kyphoplasty has not shown convincing effects in a small pilot study. Given the above mentioned methodological and clinical disputes and the call for high-evidence studies about VP, the investigators aim at generating a reliable sample size calculation and preliminary results for a future multicenter RCT about prophylactic adjacent level augmentation with VP in single level osteoporotic compression fractures.