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Fractures, Bone clinical trials

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NCT ID: NCT05865327 Recruiting - Pain Clinical Trials

UltrasouNd-guided Percutaneous Intercostal Nerve Cryoneurolysis for Analgesia Following Traumatic Rib Fracture

UNPIN
Start date: October 23, 2023
Phase: N/A
Study type: Interventional

Traumatic rib fractures (i.e., broken ribs caused by a physical injury) are common and very painful. They also often lead to serious complications, more time spent in hospital, and can even lead to death. Even after rib fractures have healed, they can lead to long-term pain and a lower quality of life. A technology called cryoneurolysis, which acts to freeze nerves causing pain using a small tool which can turn very cold, is a promising new way to manage rib fracture pain. This study is a test with a small number of people to see if it is feasible to use this technology for patients with rib fractures. If this is successful, we will recruit more people for a larger study to see if cryoneurolysis, along with standard pain control techniques, is better at stopping pain, compared to just the normal techniques alone. Participants in our study will be asked to rate their pain, and record pain medications that they take for 3 months after their pain procedure.

NCT ID: NCT05862922 Recruiting - Pain Clinical Trials

Comparison Effects of Two Regional Anesthetic Technique on Pain During High Risk Hip Fracture Surgery

Start date: November 26, 2022
Phase:
Study type: Observational

In this study, our is to compare effect of lumbosacral plexus and sacral plexus + suprainguinal fascia iliaca plane block on perioperative pain via analgesia nociceptive index monitor on high-risk patients undergoing hip fracture surgery.

NCT ID: NCT05859451 Recruiting - Smoking Clinical Trials

Effect of Tobacco Heating System (THS) on Closed Tibia Fracture Healing

Start date: June 2, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to investigate the role of switching from cigarette smoking (CS) to tobacco heat system (THS) on the clinical outcome of closed tibia fractures from smokers' orthopedic patients. Validated and standardized assays, medical state and self-reported outcomes will be evaluated in orthopedic patients' smokers or switch from CS to using THS throughout six months compare to ex-smokers (control).

NCT ID: NCT05857462 Recruiting - Hip Fractures Clinical Trials

The Impact of Integrated Preoperative Fascia Iliaca Compartment Block in Elderly Hip Fracture

Start date: May 2023
Phase: N/A
Study type: Interventional

This prospective randomized controlled study is aimed to determine the advantages of post-admission fascia iliaca compartment block (FICB) in geriatric hip fracture surgery combination with multimodal analgesia compared with no post-admission FICB. The primary outcome is incidence of delirium during hospital admission. Secondary outcomes are incidence of delirium at hospital discharge, pre- and post-operative pain intensity, peri-operative complications, opioid-related side effects, post-operative complications and length of hospital stay, and morbidities and mortality (in-hospital and 30 days).

NCT ID: NCT05851898 Recruiting - Clinical trials for Depression in Old Age

Serotonin-norepinephrine Reuptake Inhibitor in Prophylaxis of Depression Following Fragility Fractures

SNRI
Start date: April 8, 2024
Phase: Phase 4
Study type: Interventional

The goal of this pilot study is to learn about the feasibility about prescribing anti-depressants at discharge in patients aged 50 years and older with a lower extremity fragility fracture. The main questions it aims to answer are: - What are the obstacles to enrolling patients and prescribing anti-depressants among older adults? - Is it possible to start prescribing SNRI medication upon discharge? - What is the prevalence of depressive symptoms amongst patients with different types of injuries and weightbearing status? - What is a transition of care plan for patients who have geriatric depression and require further care? Participants will: - Undergo screening using the Geriatric Depression Scale - Start on Duloxetine 30mg daily at time of discharge - Report medication compliance and complete re-screening monthly - Complete patient reported outcome measures and 3 months, 6 months, and 1 year - Receive a referral to behavioral health, primary care, or psychiatrist for evaluation if they screen positive at any timepoint

NCT ID: NCT05848167 Recruiting - Clinical trials for Osteoporotic Fractures

Senile Osteoporotic Fractures Cohort Study(SOFCS)

Start date: July 15, 2021
Phase:
Study type: Observational

Osteoporotic fracture is one of the main causes of disability and death in elderly patients. Specific disease cohort study is an important basis for accurate prevention and treatment of senile osteoporotic fractures. Investigators plan to collect and manage the baseline and clinical information of more than 2000 elderly patients with osteoporotic fractures after surgery through the platform of special disease collaborative prevention and treatment system and medical record database of Suzhou Municipal Hospital in two years, and carry out short-term and long-term follow-up observation.

NCT ID: NCT05843864 Recruiting - Clinical trials for Stress Fracture of Tibia

Photobiomodulation Therapy for the Treatment of Lower Extremity Stress Fractures in a Military Training Setting

PM12
Start date: June 7, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare photobiomodulation therapy (PBMT) in addition to standard of care in the treatment of tibial and metatarsal bone stress injuries in a military training setting. Participants will all receive usual care and also be randomized to either active or sham photobiomodulation therapy. Effectiveness will be assessed based on time to return to duty and measures of pain and function. - Participants will receive care for a maximum of 6 weeks. - Participants will have follow-up through 4 months (or graduation/dismissal from training, whichever comes first).

NCT ID: NCT05842395 Recruiting - Clinical trials for Distal Radius Fracture

Vitamin c Supplementation in the Prevention of CRPS Following Distal Radius Fractures

Start date: June 15, 2023
Phase: Phase 4
Study type: Interventional

Complex Regional Pain Syndrome type 1 is a pain syndrome that develops after a trauma, surgery, or idiopathically. The incidence after distal radius varies significantly in the literature. There are known contributing factors, such as the female sex but no effective treatment or prophylactic method. This study aims to investigate vitamin C's efficacy in preventing CRPS type 1 following distal radius fractures, as the literature states that it might play a role in prophylaxis.

NCT ID: NCT05840458 Recruiting - Femoral Fracture Clinical Trials

Pericapsular Nerve Block in Proximal Femoral Fractures

Start date: April 1, 2023
Phase:
Study type: Observational

Proximal femoral fractures commonly occur above 50 years and regional anesthesia could be a complement in the perioperative treatment of the patients. The use of pericapsular nerve group block (PENG Block) has been proposed to reduce pain. However, no studies have explored the efficient of the systemic analgesia associated with PENG Block in functional limitation in the preoperative period. In this sense, the main goal of this study is to evaluate the effectiveness of systemic analgesia associated with PENG Block in patients with proximal femoral fractures in the period preceding the surgical procedure.

NCT ID: NCT05840315 Recruiting - Sarcopenia Clinical Trials

Feasibility of High Density Sit-to-stand Functional Resistance Training in Patients With Hip Fracture

Start date: March 21, 2023
Phase: N/A
Study type: Interventional

The objective of this study is to examine if functional high-density, high-volume chair rise training is feasible for increasing lower extremity strength without causing excessive hip pain during execution in patients with hip fracture following a municipality -based outpatient rehabilitation program. Feasibility criteria is defined as: 1) hip fracture-related pain might increase during the exercise programme, but not persistent after each session. 2) adherence to the program must be 75% or more. 3) Less than 20% drop-outs due to pain and/or discomfort during training.