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Foot Ulcer clinical trials

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NCT ID: NCT03863054 Completed - Diabetic Foot Ulcer Clinical Trials

An Observational Clinical Trial Examining the Effect of Topical Oxygen Therapy (NATROX™) on the Rates of Healing of Chronic Diabetic Foot Ulcers

Start date: August 17, 2018
Phase:
Study type: Observational

This study aims to evaluate the effectiveness of NATROX™ Topical Oxygen Wound Therapy for subjects with non-healing foot ulceration. Subjects will be treated with standard care for 4 weeks. If the wound is not reduced by more than 40%, NATROX™ will be applied for the next 12 weeks. Throughout the study period, wound measurements will be taken to measure wound reduction.

NCT ID: NCT03853941 Completed - Diabetes Clinical Trials

Adherence to Activity Limitations in Diabetes

Start date: March 21, 2019
Phase: N/A
Study type: Interventional

This study aims to develop and test a theory-based motivation communication training programme for healthcare professionals working with diabetic foot ulcer patients. The investigators will explore the acceptability of the training programme and examine whether the training leads to changes in healthcare professionals' communication style, and results in greater adherence to treatment recommendations (i.e., reduced weight-bearing) in patients.

NCT ID: NCT03821675 Completed - Diabetes Clinical Trials

Electrical Stimulation to Accelerate Wound Healing

Start date: February 28, 2019
Phase: N/A
Study type: Interventional

A clinical study at the Baylor College of Medicine, Division of Vascular Surgery and Endovascular Therapy, is being proposed to test the efficacy of a novel electrical stimulation platform named the Tennant Biomodulator designed by AVAZZIA to accelerate wound healing, relieve pain and improve mobility in patients with diabetic foot ulcers.

NCT ID: NCT03813927 Completed - Clinical trials for Vitamin D Deficiency

Vitamin D Treatment of Diabetic Patients With Foot Ulcers

Start date: April 1, 2016
Phase: N/A
Study type: Interventional

The purpose of this study, is to determine whether daily supplements of vitamin D improves wound healing in diabetic patients with chronic foot ulcers.

NCT ID: NCT03788642 Completed - Diabetic Foot Ulcer Clinical Trials

Low-level Laser Therapy for the Treatment of Diabetic Foot Ulcer

Start date: January 15, 2019
Phase: N/A
Study type: Interventional

The study evaluates the efficacy of Low-level laser therapy on ulcer healing in patients with diabetic foot ulcer. Half the patients are randomized to receive Low-level laser therapy and a half to recieve the placebo (LED).

NCT ID: NCT03782129 Completed - Diabetes Mellitus Clinical Trials

Five-year Mortality Rate in People With Diabetic Foot Ulcer

DIAFOOT
Start date: March 2009
Phase:
Study type: Observational

As the global mortality rate decreases for diabetics patients, further explorations and datas are needed about the specific population of diabetics patients suffering a Diabetic Foot Ulcer (DFU). This study investigates the 5 years mortality rate in patients with a diabetic foot ulcer occurring in 2010.

NCT ID: NCT03742440 Completed - Diabetic Foot Ulcer Clinical Trials

GrafixPL PRIME Evaluation Case Study

Start date: November 20, 2018
Phase: Phase 4
Study type: Interventional

The investigators plan to evaluate healing in a cohort of patients with chronic wounds (n=40) that receive optimal treatment including serial wound debridement and off-loading with total contact casts or a boot and GrafixPL PRIME. In addition, the investigators will collect data on other potential confounding factors that could affect healing such as medications, tobacco, nutrition, comorbidities, diabetes control, infection, perfusion, and activity. Wound healing, including wound size and adverse events will be evaluated. The objective of this study is to understand the use of this product to evaluate wound healing in 40 patients.

NCT ID: NCT03717233 Completed - Diabetic Foot Ulcer Clinical Trials

Assistive ExoSkeletons to Enable Wearable Rehabilitation Robotics

Start date: October 18, 2018
Phase: N/A
Study type: Interventional

Study will evaluate the use of lower-limb assistive exo-skeletons worn on the ankle and foot. Participants will wear the exo-skeletons and walk in a safe environment. Measurements will be taken to determine how the exo-skeletons affect the pressure on the feet of people with diabetic foot ulcer and how they walk.

NCT ID: NCT03716141 Completed - Diabetic Foot Ulcer Clinical Trials

Autologous Platelets Rich Plasma (APRP) Treatment Vs Saline Dressing for the Management of Diabetic Foot Ulcer

APRP
Start date: January 1, 2018
Phase: N/A
Study type: Interventional

The aim of this study is to compare between the platelet rich plasma and normal saline dressing in the healing diabetic foot ulcers. It will be a randomized controlled trial.

NCT ID: NCT03700580 Completed - Diabetic Foot Clinical Trials

Clinical Trial Using the Proteolytic Fraction P1G10 From V. Cundinamarcensis to Heal Diabetic Foot Ulcer

P1G10
Start date: August 15, 2012
Phase: Phase 2
Study type: Interventional

The aim of the study was to investigate the role of the proteolytic fraction from Vasconcellea cundinamarcensis, designated as P1G10, on healing of chronic foot ulcers in neuropathic patients diagnosed with diabetes type 2. Fifty patients were enrolled in a prospective, randomized, double-blind trial, to verify the efficacy and safety of a topical dressing containing 0.1% P1G10, versus a Hydrogel (positive control) protocol currently applied at the Health Center to treat this condition. Upon completion of the intervention, the outcome evaluated the number of patients attaining full epithelization (100%), or at least 80% healing in both arms (P1G10 versus Hydrogel). Statistical analysis compared the endpoint data on each group to assess the significance of differences.