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Fistula clinical trials

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NCT ID: NCT03467542 Completed - Clinical trials for Arteriovenous Dural Fistula

PHIL in the Treatment of Intracranial dAVF.

PHIL dAVF
Start date: August 24, 2018
Phase: N/A
Study type: Interventional

This study is a prospective, multicenter, single-arm study. Patients with Dural Arteriovenous Fistulas (dAVF) have a few choice for safe treatment. In this study, all patients with qualifying dAVFs will be treated with PHIL® Liquid Embolic material.

NCT ID: NCT03466515 Completed - Crohn Disease Clinical Trials

Stem Cells Treatment of Complex Crohn's Anal Fistula

fistula
Start date: June 1, 2018
Phase: N/A
Study type: Interventional

A pilot study to investigate the safety and feasibility of stem cells treatment of complex anal fistula in patients with Crohn's disease.

NCT ID: NCT03449069 Completed - Crohn Disease Clinical Trials

Pediatric MSC-AFP Sub-study for Crohn's Fistula

Start date: July 23, 2018
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the safety of using an autologous mesenchymal stromal cell (MSC) coated fistula plug in people with fistulizing Crohn's disease. Autologous means these cells to coat the plug come from the patient.

NCT ID: NCT03419676 Completed - Pancreatic Fistula Clinical Trials

Use of Hemopatch as a Sealant at the Pancreaticojejunostomy After Pancreatoduodenectomy

Start date: May 1, 2018
Phase: Phase 3
Study type: Interventional

The objective of this study is to determine the effect of the sealant patch Hemopatch, compared to current practice without any sealant, on the decrease of the postoperative pancreatic fistula on patients undergoing pancreatoduodenectomy for benign or malignant tumors or other benign process.

NCT ID: NCT03410914 Completed - Surgery Clinical Trials

Intra-operative Application of HEMOPATCH to the Pancreatic Stump to Prevent Post-operative Pancreatic Fistula Following Distal Pancreatectomy

PATCH-DP
Start date: August 13, 2018
Phase: Phase 2
Study type: Interventional

Despite improvements and advances in pancreas surgery, about 30-35% of patients who have pancreas surgery develop a type of complication called a pancreatic fistula. A pancreatic fistula occurs when fluid produced by the pancreas leaks into the abdomen after pancreas surgery. Patients who develop a pancreatic fistula can have poor short-term and long-term consequences.We are studying the effect of a medical device named HEMOPATCH on the development and seriousness of pancreatic fistulas. HEMOPATCH is a thin, flexible bovine protein-based pad that may improve tissue sealing where it is applied during surgery. Some small studies called case studies of between 2 and 7 patients, and two clinical trials have shown that HEMOPATCH is effective at stopping bleeding and reducing drain output after some types of surgery. However, there have been no completed clinical trials using HEMOPATCH to prevent or reduce pancreatic fistulas in patients having pancreas surgery, so we don't know if it works in this setting. Health Canada has approved the use of HEMOPATCH as a device to stop bleeding or seal other bodily fluids for procedures in which the control of bleeding or leakage of other body fluids or air by standard surgical techniques are either ineffective or impractical.

NCT ID: NCT03405922 Completed - Hemorrhoids Clinical Trials

Perianal Nerval Block in Proctological Interventions

Start date: February 1, 2018
Phase: Phase 4
Study type: Interventional

The aim of this study is to evaluate whether a local perianal block performed during a proctological intervention can reduce the postoperative pain.

NCT ID: NCT03366727 Completed - Clinical trials for Arteriovenous Fistula Stenosis

AcoArt III / Arterio-venous Fistula in China

Start date: May 1, 2018
Phase: N/A
Study type: Interventional

This trial is aimed to evaluate the safety and efficacy of DCB in treating AVF stenosis in chinese population.

NCT ID: NCT03349424 Completed - Pancreatic Fistula Clinical Trials

Somatostatin Prevent Post-operation Pancreatic Fistula in Intermediate Risk Patients After Pancreaticoduodenectomy

Start date: June 22, 2018
Phase: Phase 4
Study type: Interventional

This study is designed to assess the preventive effects of somatostatin on post-operation pancreatic fistula in intermediate risk patients after pancreaticoduodenectomy. Patients assigned into the treatment group will be continuous intravenous infusion with the somatostatin (Stilamin®) in addition to conventional treatments (including infection prevention, nutrition support and acid suppression therapy, etc.).The pancreatic fistula incidence will be monitored within 30 days after operation.

NCT ID: NCT03345511 Completed - Pain, Postoperative Clinical Trials

Ultrasound Guided Caudal Block for Benign Anal Surgery

Start date: November 1, 2015
Phase: N/A
Study type: Interventional

Interventional study that evaluate analgesia and side effects of Ultrasound guided Caudal block preoperatively in benign canal anal surgery

NCT ID: NCT03321266 Completed - Anorectal Fistula Clinical Trials

Retrospective Review of the Cook Biodesign® Fistula Plug to Treat Anorectal Fistulas

Start date: November 30, 2017
Phase:
Study type: Observational

The study is a retrospective review of the use of the Biodesign® Fistula Plug (C-FPS-[X]). A total of 73 patients will be enrolled who have had a fistula plug placed to treat anorectal fistulas and will therefore be eligible for statistical analysis.