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Fatty Liver clinical trials

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NCT ID: NCT04411862 Completed - Clinical trials for Non-Alcoholic Fatty Liver Disease

Efficacy of Phosphatidylcholine in NAFLD

Start date: January 2, 2016
Phase: Phase 3
Study type: Interventional

This study evaluates efficacy of Phosphatidylcholine in addition to life style modification and patient health education by clinical Pharmacist in the Management of Non Alcoholic Fatty Liver NAFLD. All participants with NAFLD will receive life style intervention and half of them will receive additionally Phosphatidylcholine.

NCT ID: NCT04399538 Completed - Clinical trials for Nonalcoholic Steatohepatitis

Study of Pharmacodynamics and Safety of DGAT2i and ACCi Coadministered in Participants With Sponsor-defined Presumed Non Alcoholic Steatohepatitis

Start date: August 10, 2020
Phase: Phase 2
Study type: Interventional

The study will evaluate the effect of coadministration of a range of doses of DGAT2i with 1 dose of ACCi, on hepatic steatosis and the ability of DGAT2i to mitigate ACCi-induced elevations in serum triglycerides. The study has a 2-part design with sequential conduct of Part 1 and Part 2 with each part conducted in distinct/separate cohorts of participants. The overall study design, objectives/endpoints, eligibility criteria for both parts is envisioned to be identical, however, data from Part 1 will be used to determine whether to conduct Part 2.

NCT ID: NCT04389775 Completed - Obesity Clinical Trials

To Evaluate the Safety, Tolerability, PK, and PD of XW003 Injection in Healthy Adult Participants

XW003
Start date: March 29, 2020
Phase: Phase 1
Study type: Interventional

XW003 is an acylated human GLP-1 analogue and is being development for diabetes mellitus, obesity and nonalcoholic steatohepatitis (NASH) management. This is a first-in-human (FIH), single-centre, double blind, randomised, SAD and MAD study of XW003 conducted in healthy adult participants. The study is designed to evaluate the safety, tolerability, PK, and PD of XW003 in healthy adult participants.

NCT ID: NCT04384159 Completed - Clinical trials for Non-Alcoholic Fatty Liver Disease

Combination Diagnostic Strategies in NAFLD

CombinationSSI
Start date: November 30, 2011
Phase:
Study type: Observational

Serial combination of biological and elastography tests is accurate to diagnosing advanced fibrosis in non-alcoholic fatty liver disease (NAFLD) patients. In this study, the investigators compared the diagnostic performances of a 2-step strategy using either vibration-controlled transient elastography (VCTE) or bidimensional shear wave elastography with Supersonic imagine (2D-SWE-SSI), and analysed the added-value of a 3-step strategy.

NCT ID: NCT04367012 Completed - Fatty Liver Disease Clinical Trials

Fatty Liver Among Employees at Banha University

fattyliver
Start date: April 19, 2018
Phase:
Study type: Observational

This was cross sectional study at Banha University Hospital among employees. Age of the subjects from 20-60 years old both males and females .All investigations done plus abdominal ultrasound for grading of fatty liver and dopler for carotid intima media thickness.

NCT ID: NCT04342793 Completed - Clinical trials for Nonalcoholic Steatohepatitis

A Study to Evaluate the Efficacy and Safety of ALS-L1023 in Subjects With NASH

Start date: December 4, 2019
Phase: Phase 2
Study type: Interventional

The main objective of this study is to evaluate safety and efficacy of ALS-L1023 in patients with Non-alcoholic steatohepatitis

NCT ID: NCT04342390 Completed - Insulin Resistance Clinical Trials

Effects of High-Intensity Interval Training Exercise in Adolescents With Hepatosteatosis

Start date: April 2, 2021
Phase: N/A
Study type: Interventional

This is a research study about how short-term exercise intervention affects adolescents with a disease called non-alcoholic fatty liver disease (NAFLD).

NCT ID: NCT04341246 Completed - Clinical trials for Non-Alcoholic Fatty Liver Disease

Characterization and Technical Evaluation of cT1 for NASH (CATE-NASH)

Start date: January 28, 2021
Phase:
Study type: Observational

The primary objective of this study is to evaluate to provide evidence to establish tightly defined cut-offs to identify patients for NASH clinical trial inclusion using cT1 and/or PDFF. The study will be divided into 2 sub groups comprising of cases and controls.

NCT ID: NCT04336800 Completed - Clinical trials for Diabetes Mellitus, Type 2

Multi-Parametric MRI Assessment of the Liver in Diabetic Volunteers (Partners Registry)

Start date: April 1, 2020
Phase:
Study type: Observational

To build a registry of diabetic volunteers by inviting them to get a LiverMultiScan and collecting their contact information to seek interest in participating in future research studies.

NCT ID: NCT04336618 Completed - Clinical trials for Non-Alcoholic Fatty Liver Disease

Multi-Parametric MRI Assessment of the Liver in the Dallas-FortWorth Metroplex Population

DFWRegistry
Start date: August 3, 2020
Phase:
Study type: Observational

To build a Registry of volunteers by inviting them to get a LiverMultiScan(LMS)and collecting their contact information to seek interest in participating in future studies.