Exercise Clinical Trial
Official title:
The Influence of 5-HTTLPR and BDNF Polymorphisms on Anxiety and Mood After Acute Exercise
The Influence of 5-HTTLPR and BDNF Polymorphisms on Anxiety and Mood After Acute Exercise.
Introduction: The 5-HTTLPR (SLC6A4) and BDNF (Val66Met) polymorphism presents an action on
the modulation of human behavior and has received great attention as a risk factor for
several psychiatric disorders. In recent years, a growing number of studies have evaluated
the association between these polymorphisms and personality traits related to anxiety and
depression. Objectives: To determine the frequencies of 5-HTTLPR and BDNF polymorphisms in a
college students population; To determine the influence of 5-HTTLPR and BDNF polymorphisms on
mood states and anxiety after acute physical exercise. Material and Methods: Four hundred
(400) College students will be assessed.
In the first phase of the study, the following procedures will be performed: Screening,
Aerobic Fitness Assessment (Step Test), Questionnaires (PAR-Q, Habitual Physical Activity
Level, Beck Anxiety and Depression Scale, State-Trait Anxiety, and Perceived Stress Scale),
blood sample collection and genotyping. In the second phase of the study, two (2) groups with
or without polymorphisms will be selected (for each gene). These groups will be submitted to
four conditions (three experimental conditions and one control condition), carried out
randomly and separated by an interval of 1 week. In the experimental Conditions the
volunteers will perform treadmill exercises sessions (30 minutes) in three different
intensities (light, moderate and vigorous) and will respond to the Borg Scale at 10, 20 e 30
minutes. In the control condition the volunteers will be instructed to remain seated (quiet
rest), relaxed and silent for 30 minutes. In both conditions, the volunteers will complete
the Profile of Mood States (POMS) and State-Anxiety (STAY), 05 (five) minutes before and, 5
(five) and 20 (twenty) minutes following the interventions.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05156424 -
A Comparison of Aerobic and Resistance Exercise to Counteract Treatment Side Effects in Men With Prostate Cancer
|
Phase 1/Phase 2 | |
| Completed |
NCT05108181 -
Muscle Typology and Strength Training Adaptations
|
N/A | |
| Recruiting |
NCT05052918 -
The Effect of Exercise and Metformin on Carotid Intima-media Thickness in Patients With Prediabetes
|
N/A | |
| Completed |
NCT04508270 -
Significance of Early Mobilization After VATS-L
|
||
| Recruiting |
NCT04994340 -
Physical Activity Observatory of Castilla-La Mancha
|
||
| Completed |
NCT04815980 -
Impact of Pilates on Running Mechanics
|
N/A | |
| Completed |
NCT05189795 -
The Construction of Physical ACtivity Enhancement Scheme (PACES) in Hemodialysis Patients
|
||
| Completed |
NCT03683758 -
Effects of the FIFA11+ Warm-up Program on Speed, Agility, and Vertical Jump Performance in Adult Female Amateur Soccer Players
|
N/A | |
| Completed |
NCT05538520 -
Effects of Pilates Stretching on Flexibility, Strength, Power and Muscular Endurance
|
N/A | |
| Completed |
NCT06315036 -
Effects of Developmental Gymnastics on Preschoolers' Motor Skills
|
N/A | |
| Completed |
NCT03171064 -
Exercise as a Supportive Measure for Patients Undergoing Checkpoint-inhibitor Treatment
|
Phase 2 | |
| Recruiting |
NCT05496751 -
Response Variability to Exercise
|
N/A | |
| Not yet recruiting |
NCT05029804 -
Effect of Walking Exercise Training on Adherence to Disease Management and Metabolic Control in Diabetes
|
N/A | |
| Completed |
NCT04207359 -
Effects of Creatine Supplementation in Breast Cancer Survivors
|
N/A | |
| Completed |
NCT04099654 -
The Effect of Core Stabilization Exercise Program in Obese Subjects Awaiting Bariatric Surgery
|
N/A | |
| Completed |
NCT03832205 -
Validation of Respiratory Rate and Heart Rate Measurements by Capaciflectors Placed in Four Locations on the Chest
|
||
| Completed |
NCT03297567 -
Physical Therapy Guidelines For Hospitalized Elderly
|
N/A | |
| Completed |
NCT03477188 -
The Effects of Somatosensory and Vestibular Rehabilitation Additional Conventional Therapy on Balance in Patients With Acute Stroke.
|
N/A | |
| Recruiting |
NCT05956327 -
Insight Into Hippocampal Neuroplasticity in Schizophrenia by Investigating Molecular Pathways During Physical Training
|
N/A | |
| Recruiting |
NCT06018311 -
Exercising Together for Hispanic Prostate Cancer Survivor-Caregiver Dyads
|
N/A |