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Esophagitis clinical trials

View clinical trials related to Esophagitis.

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NCT ID: NCT03029091 Completed - Clinical trials for Eosinophilic Esophagitis

An Open-Label Trial of Losartan Potassium in Participants With Eosinophilic Esophagitis (EoE)

Start date: May 23, 2017
Phase: Phase 2
Study type: Interventional

The purpose of this study is to test the safety and effectiveness of Losartan potassium in subjects with eosinophilic esophagitis (EoE) including those with a connective tissue disorder (CTD) and those without a CTD.

NCT ID: NCT03006874 Completed - Erosive Esophagitis Clinical Trials

Study to Confirm the Safety and Efficacy of CJ-12420 in Patients With Erosive Esophagitis

Start date: May 2, 2016
Phase: Phase 3
Study type: Interventional

The purpose of this study is to confirm the efficacy of CJ-12420, Once daily (QD), compared to esomeprazole in patients with erosive esophagitis classified as Los Angeles (LA) classification grades A to D at Week 8.

NCT ID: NCT02995395 Completed - Healthy Clinical Trials

Mucosal Impedance Balloon in Diagnosis and Treatment of Eosinophilic Esophagitis (EoE)

Start date: October 1, 2017
Phase:
Study type: Observational

This study will evaluate the role the balloon mucosal impedance may have in diagnosing and monitoring the patients with Eosinophilic Esophagitis. We will compare the results of the balloon mucosal impedance in patients with Eosinophilic esophagitis and controls.

NCT ID: NCT02995239 Completed - Erosive Esophagitis Clinical Trials

A Study to Compare the Pharmacokinetic Characteristics of CJ-12420

Start date: April 2015
Phase: Phase 1
Study type: Interventional

To compare the pharmacokinetics after administration of different formulation of CJ-12420

NCT ID: NCT02897271 Completed - Clinical trials for Eosinophilic Esophagitis

Characteristics of Eosinophilic Gastritis, Enteritis, and Colitis in a Multi-Site Cohort

Start date: August 2016
Phase:
Study type: Observational

The purpose of this study is to investigate features of patients with Eosinophilic Gastrointestinal Disorders (EGIDs) other than Eosinophilic Esophagitis (EoE) alone, including Eosinophilic Gastritis (EG), Eosinophilic Gastroenteritis (EGE), and Eosinophilic Colitis (EC).

NCT ID: NCT02778867 Completed - Clinical trials for Eosinophilic Esophagitis (EoE)

SOFEED: Six Food vs. One Food Eosinophilic Esophagitis Diet Study

SOFEED
Start date: May 20, 2016
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this interventional study is to test and compare the effectiveness of two elimination diets—the 1-food elimination diet (1FED, milk only) and the 6-food elimination diet (6FED, milk, egg, wheat, soy, tree nut/peanuts, and fish/shellfish). The study will also test the effectiveness of swallowed glucocorticoid therapy in some of the study participants for whom diet therapy was not effective.

NCT ID: NCT02775045 Completed - Clinical trials for Eosinophilic Esophagitis

Eosinophil β1 Integrin Activation as a Biomarker for Eosinophilic Esophagitis

EoE
Start date: August 30, 2016
Phase:
Study type: Observational

The purpose of this study is to improve the overall management of patients with Eosinophil Esophagitis. Currently, the best way to monitor Eosinophil Esophagitis is repeating the endoscopy procedure. The investigators plan to identify a biomarker in the blood (a measurable substance) that tracks with disease activity and will reduce the need for follow-up endoscopies.

NCT ID: NCT02755753 Completed - Clinical trials for Gastroesophageal Reflux

A Study to Evaluate REbamiPide as an Adjuvant Regimen to Heal erosIve Reflux Esophagitis

REPAIR
Start date: January 2014
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate whether Rebamipide facilitate the healing of inflamed mucosa as an adjuvant regimen in erosive reflux esophagitis (ERE).

NCT ID: NCT02736409 Completed - Clinical trials for Eosinophilic Esophagitis (EoE)

An Extension Study to Evaluate Maintenance of Efficacy and Long-term Treatment Effect of Oral Budesonide Suspension (OBS) in Adults and Adolescents With Eosinophilic Esophagitis (EoE)

ORBIT2
Start date: April 1, 2016
Phase: Phase 3
Study type: Interventional

This is a multicenter, double- blind extension study of Oral Budesonide Suspension (OBS) in adults and adolescents (11 to 55 years of age, inclusive) with Eosinophilic Esophagitis (EoE) who have completed participation in the SHP621-301 induction study (NCT02605837). The primary objective is to evaluate the maintenance of efficacy of OBS over 36 weeks. Maintenance of efficacy will be measured by the peak eosinophilic count and Dysphagia Symptom Questionnaire (DSQ) score.

NCT ID: NCT02722148 Completed - Clinical trials for Eosinophilic Esophagitis

Application of a Novel Allergen-Specific Immune Signature Directed Approach to Dietary Elimination Therapy in Patients With Eosinophilic Esophagitis (IDiET)

IDiET
Start date: April 21, 2016
Phase: N/A
Study type: Interventional

This is a prospective single center clinical trial of allergen-specific immune signature-guided dietary elimination therapy to assess the clinical effectiveness of this technique.