RESEARCH EVALUATING VAGAL EXCITATION AND ANATOMICAL LINKS

Status Recruiting

Clinical Trial Summary

The acute and chronic effects of VNS stimulation on various on the autonomic nervous, cardiovascular, immune, and metabolic systems will be compared from noninvasive and minimally invasive physiological recordings and blood draws at various time points throughout the study. These interventions and assessments will be performed in individuals 18 years of age and older who are implanted with a VNS device, which consists of patients who have been diagnosed with drug resistant epilepsy or major depressive disorder. The REVEAL study is not a treatment study; its primary objective is to scientifically investigate the contributing roles of efferent versus afferent vagus nerve modulation of multiple peripheral organs and their dependence on stimulation parameters, in which participants are those who have been implanted with a VNS device be receive standard of care treatment for their epilepsy or depressive disorder.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06143293
Study type	Interventional
Source	University of Minnesota
Contact	Kathryn Vera
Phone	612-625-5018
Email	giero002@umn.edu
Status	Recruiting
Phase	N/A
Start date	December 15, 2023
Completion date	December 15, 2025

View Details

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