Bipolar Disorder in Epilepsy

Epilepsy Clinical Trial

Official title:

Bipolar Disorder in Epilepsy

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00365482
• Other study ID #: 06.02.029
• Status: Completed
• Phase: N/A
• First received: August 15, 2006
• Last updated: May 15, 2012
• Start date: August 2006
• Est. completion date: December 2011

Study information

• Verified date: May 2012
• Source: Northwell Health
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

The purpose of this study is to find out how often major mood swings occur in patients treated in a specialty epilepsy center.

Description:

Bipolar disorder (a condition of major mood swings) or milder forms of ups and downs in mood may occur with a number to neurological conditions. Recently, one study showed that these mood changes occur fairly often in individuals with epilepsy studied in the general community. We speculate that bipolar symptoms occur with even higher frequency in a tertiary epilepsy center than that encountered in the previous community-based study. The goals of this study are to assess:

• the rate of bipolar symptoms as measured by a self-reporting screening tool in a tertiary epilepsy center setting

• the meaning of a positive screening score in epilepsy patients

• the utility, sensitivity and specificity of alternative screening tools for mood instability in epilepsy patients

• the correlation of mood instability with seizure-related variables

• the relation of a positive screening score on quality of life.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 102
• Est. completion date: December 2011
• Est. primary completion date: December 2011
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Male or female 18 years of age or older

• Being evaluated at the Long Island Jewish Comprehensive Epilepsy Center

• Capable of completing self-reporting questionnaires

Exclusion Criteria:

• Patients with mental retardation

• Patients with pseudoseizures

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

• Bipolar Disorder
• Epilepsy

Locations

Country	Name	City	State
United States	North Shore Long Island Jewish Health System	Great Neck	New York

Sponsors (2)

Lead Sponsor	Collaborator
Northwell Health	GlaxoSmithKline

Country where clinical trial is conducted

United States,