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Epilepsy clinical trials

View clinical trials related to Epilepsy.

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NCT ID: NCT00771927 Completed - Epilepsies, Partial Clinical Trials

Post-Authorization Safety Study to Assess the Safety of Vimpat as add-on Therapy in Patients With Partial-onset Seizures

PASS
Start date: October 2008
Phase: N/A
Study type: Observational

SP942 is a non-interventional post-authorization safety study (PASS) to evaluate the long-term safety and tolerability of Vimpat® (Lacosamide, LCM) as add-on treatment in patients with Epilepsy 16 years and older with partial-onset seizures who are uncontrolled on current therapy. Using reported adverse events, the incidence of certain cardiovascular and psychiatric events will be evaluated.

NCT ID: NCT00767026 Completed - Epilepsy Clinical Trials

COPE Intervention for Parents of Children With Epilepsy

Start date: January 2008
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine if the program Creating Opportunities for Parent Empowerment (COPE) is feasible to administer to parents of children with neurological conditions. The goal of the study is to empower parents by providing them with educational materials designed to teach them how to foster healthy coping skills in their child.

NCT ID: NCT00761774 Completed - Epilepsy Clinical Trials

An Open-label, Multinational, Multicenter, Follow-up Study to Evaluate the Long-term Safety and Efficacy of Brivaracetam

Start date: November 2008
Phase: Phase 3
Study type: Interventional

The Sponsor wishes to develop brivaracetam as an anti-epileptic treatment in subjects 16 years and older with epilepsy. This study permits continued access to treatment for subjects who participated in a previous epilepsy study. The study will explore the long-term safety and efficacy of brivaracetam.

NCT ID: NCT00753493 Completed - Epilepsy Clinical Trials

Pharmacokinetics and Safety of Intravenous Topiramate in Adult Patients

Start date: August 2008
Phase: Phase 1
Study type: Interventional

The aims of this study are to determine, in adult patients on maintenance topiramate therapy, the steady-state pharmacokinetics and safety of orally and intravenously administered topiramate.

NCT ID: NCT00744731 Completed - Clinical trials for Epilepsy, Complex Partial

An Open-Label Extension Study of the Safety and Tolerability of Carisbamate as Add-On Therapy in Patients With Partial Onset Seizures

Start date: January 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to obtain long-term safety and tolerability information on carisbamate as add-on therapy for the treatment of partial onset seizures in patients with epilepsy. Seizure counts will be obtained to measure the rate of seizures for each patient during the study.

NCT ID: NCT00741559 Completed - Epilepsy Clinical Trials

Combined Role of Position Emission Tomography (PET) and Magnetoencephalography (MEG) in Nonlesional Epilepsy

Start date: March 2008
Phase: Phase 3
Study type: Interventional

The first aim of this study are to evaluate the lobar concordance of FDG-PET and MEG with intracranial electrographic study in children with intractable partial epilepsy. The second aim is to determine if the combined role of FDG-PET and MEG improve detection of epileptogenic zone as defined by invasive intracranial recordings.

NCT ID: NCT00740623 Completed - Clinical trials for Epilepsy, Complex Partial

A Study of the Effectiveness, Safety, and Tolerability of Carisbamate as Add-On Therapy in Patients With Partial Onset Seizures.

Start date: January 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the effectiveness, safety, and tolerability of carisbamate as add-on therapy for the treatment of partial onset seizures in patients with epilepsy.

NCT ID: NCT00736931 Completed - Epilepsy Clinical Trials

Clinical Study in Healthy Volunteers to Investigate the Neurocognitive Effects of a New Antiepileptic Drug: Brivaracetam

Start date: July 2008
Phase: Phase 1
Study type: Interventional

The primary objective of the study is to evaluate the neurocognitive effects of brivaracetam

NCT ID: NCT00736424 Completed - Epilepsy Clinical Trials

Brain Stimulation for Epilepsy Long Term Follow-up

SUDEP
Start date: June 2008
Phase: N/A
Study type: Observational

The purpose of this study is to collect subject data to evaluate the rate of sudden unexplained death in epilepsy (SUDEP) with bilateral neurostimulation of the anterior nucleus of the thalamus in people diagnosed with refractory epilepsy. The data obtained from the physician initiated studies will be pooled with data collected in Medtronic-sponsored studies to assess SUDEP risk.

NCT ID: NCT00735397 Completed - Epilepsy Clinical Trials

Evaluation of the Efficacy and Safety of E2007 (Perampanel) Given as Adjunctive Therapy in Subjects With Refractory Partial Seizures

Start date: October 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study was to evaluate the safety and tolerability of perampanel (up to 12 mg/day) given as adjunctive treatment in subjects with refractory partial seizures and to evaluate the maintenance of effect of perampanel for the control of refractory partial seizures.