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Emergencies clinical trials

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NCT ID: NCT04730661 Recruiting - SARS-CoV Infection Clinical Trials

Efficacy of the Sit to Stand Test in the Decision to Hospitalize a Patient Consulting the Emergency Dept for COVID 19

SITCOV
Start date: December 21, 2020
Phase: N/A
Study type: Interventional

As part of the Coronavirus Infectious Disease 2019 (COVID19) pandemic, the hospital care system is facing a major strain. Patients with SARS-Cov2 (severe acute respiratory syndrome coronavirus 2 ) infection can worsen very quickly, possibly presenting, within hours, severe respiratory failure requiring urgent specialized care. Therefore, it is essential to develop emergency assessment tools to assess relevant criteria to decide which patients must be kept under hospital monitoring and which patients can be treated on outpatient care. The aim of this study is to assess the efficacy of STST in the decision to hospitalize patients consulting emergency department for a SARS-Cov2 infection. The investigators wish to show that the addition of this test to the usual hospitalization criteria reduces the proportion of patients hospitalized 48 hours after their first visit to the emergency department.

NCT ID: NCT04726592 Recruiting - Migraine Clinical Trials

Efficacy of CLORazepate for the Treatment of MIGraine Attack in the Emergency Room

Start date: July 8, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy of clorazepate in addition to the usual medication for treating migraine attack in the emergency room

NCT ID: NCT04725968 Completed - Emergencies Clinical Trials

Morbimortality in Major Urgent General Surgery in the Geriatric Patient.

Start date: January 28, 2021
Phase:
Study type: Observational

Retrospective observational cohort study of geriatric patients operated of urgent major general surgery in our centre during 2018. Our principal goals are: 1. To evaluate the incidence of post operation complications and its severity (defined by the Claiven-Dindo scale) 2. To evaluate the mortality: global mortality and mortality after: 30 days, 6 months and 1 year.

NCT ID: NCT04722588 Active, not recruiting - Clinical trials for Emergency Department

Integrating the Clinical Pharmacists Into Emergency Department Teams

ED-PHARM
Start date: February 1, 2021
Phase: N/A
Study type: Interventional

The "Emergency Department (ED) Pharmacist" is an integrated part of the ED interdisciplinary team in many countries, which have shown to improve medication safety and reduce costs related to hospitalisations. In Norway, few EDs are equipped with an ED pharmacist, and research describing effects on patients has not been conducted. This is a multicentre study where the intervention will be implemented in the regular operation of three EDs in Northern Norway; Tromsø, Bodø and Harstad. Clinical pharmacists will work as an integrated part of the ED team, and provide pharmaceutical care services such as medication reconciliation, medication review or medication counselling. The medical condition and complexity of the patient's disease will influence the extend and type of service from the pharmacist. A non-randomized stepped wedge study design will be applied, where the ED pharmacist will be implemented in all three EDs after a three, six- and nine- month control period, respectively. Each ED will consequently have both intervention and control periods. All patients going through the three EDs during the 12-month study period will be included. Patients admitted in the control periods will be allocated to the control group, while patients admitted in the intervention periods will be allocated to the intervention group. The primary endpoint is "Time in hospital during 30 days after admission to the ED", which is a composite endpoint combining i) time in ED during stay, ii) time in hospital during stay if hospitalized and iii) time in urgent care clinic, ED and/or hospital if rehospitalized within 30 days after admission to ED Secondary endpoints include time to rehospitalization, length of stay (LOS) during first hospitalisation, LOS in EDs, rehospitalisation rates and mortality rates. Patient data will be collected retrospectively from national data registries, from the hospital system and from patient records. The Regional Committee for Medical and Health Research Ethics and Local Patient Protection Officers in all hospitals have approved the study.

NCT ID: NCT04721275 Recruiting - Sepsis Clinical Trials

Evaluation of the Performance of Sepsis Predictive Scores on the Elderly Population in the Emergency Department.

Start date: January 18, 2021
Phase:
Study type: Observational

The main objective of the research is to evaluate the prognostic performance of qSOFA, NEWS and MEDS scores in patients over 65 years of age presenting to the emergency department with a diagnosis of infection made by the emergency physician in charge. The main judgment criterion is intra-hospital mortality. Secondary criteria for judgement are admission to intensive care or intensive care (continuous monitoring unit), length of hospital stay, length of stay in the emergency room, length of time before antibiotic therapy is administered. A comparison of score performance will be carried out between the population aged over 65 years old and the rest of the population.

NCT ID: NCT04717830 Recruiting - Ebola Virus Disease Clinical Trials

An Open Study of the Safety and Pharmacokinetics of a Drug for the Emergency Prevention of Ebola Virus Disease

Start date: February 15, 2021
Phase: Phase 1
Study type: Interventional

Open-label safety, tolerability, pharmacokinetics and immunogenicity study in three dose escalation groups

NCT ID: NCT04717518 Completed - Neck Pain Clinical Trials

Anchoring Patients Pain Scores in the Emergency Department

Start date: August 24, 2020
Phase:
Study type: Observational

The proposed research will be a prospective, observational study to test the hypothesis that anchoring will affect verbal pain scores in the emergency department. There will be a small retrospective aspect to this study to obtain patient satisfaction ratings.

NCT ID: NCT04715854 Active, not recruiting - Covid19 Clinical Trials

Effect on paO2 of Adding an Aerosol Mask Above the Nasal Canulas

Start date: February 19, 2021
Phase: N/A
Study type: Interventional

This study will compare the impact of a classical aerosol mask above low-flow nasal cannula on the arterial oxygen tension in patients with COVID-19.

NCT ID: NCT04705961 Completed - Clinical trials for Surgery--Complications

Bile Leakage Test in Emergency Hydatid Liver Cyst Surgery Case Report

Start date: January 1, 2018
Phase:
Study type: Observational [Patient Registry]

In liver cyst hydatid surgery, presence of cysto-biliary communication (CBC) is important for the prevention of postoperative morbidity. If cysto-biliary connections are not obvious, diagnosis is not easy. Intraoperative bile leakage test has been shown to reduce postoperative biliary complications by revealing occult CBCs. However, bile leakage testing in emergency conditions such as hydatid cyst perforation has not been experienced so far.

NCT ID: NCT04702945 Recruiting - Covid-19 Clinical Trials

Canadian COVID-19 Emergency Department Registry

CCEDRRN
Start date: March 1, 2020
Phase:
Study type: Observational [Patient Registry]

Coronavirus Disease 2019 (COVID -19) is the largest public health crisis in over a century. There is an urgent need for high-quality population-level data to understand modifiable risks for disease severity, transmissibility, and to develop evidence-based prevention (i.e. vaccination), treatment and resource allocation strategies. The Canadian COVID-19 Emergency Department Rapid Response Network (CCEDRRN) created a population-based registry of suspected and confirmed consecutive cases of COVID-19. The purpose of this registry is to derive and validate clinical decision rules, evaluate diagnostic tests and vaccine effectiveness, and complete cohort, case-control and observational studies to inform the pandemic response.