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Embolism clinical trials

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NCT ID: NCT05353608 Completed - COVID-19 Clinical Trials

Lung Scintigraphy for Pulmonary Embolism Diagnosis in COVID-19 Patients.

SCINTI-COVID
Start date: April 30, 2021
Phase:
Study type: Observational

A frequent complication of COVID-19 disease is pulmonary embolism (PE). Lung ventilation/perfusion (V/P) scintigraphy is a well-established test for PE diagnosis. The test is interpreted based on the recognition of wedge shaped perfusion mismatched defects. However, the ventilation procedure increases the potential risk of contamination by the aerosol secretion and the expired air. A variety of strategies have been proposed in the nuclear medicine literature regarding performance of lung ventilation scintigraphy in COVID-19 patients with suspected acute PE. However, there is currently no factual data in this specific population to support recommendations to the nuclear medicine community. The aim of this study was to assess the role of ventilation imaging when performing lung scintigraphy for suspected PE in COVID-19 patients.

NCT ID: NCT05351749 Recruiting - Atrial Fibrillation Clinical Trials

Implementing Prescriber-Pharmacist Collaborative Care for Evidence-based Anticoagulant Use

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

The researchers hypothesize that existing-prescription notifications directed to pharmacists are more likely to lead to a prescription change than existing-prescription notifications directed to prescribers. Furthermore, the researchers hypothesize that the availability of a pharmacist referral option is associated with a higher rate of prescription changes for initial-prescription alerts that are directed to the prescriber at the time of initial-prescribing errors. Findings from this project will establish a framework for implementing prescriber-pharmacist collaboration for high risk medications, including anticoagulants

NCT ID: NCT05341258 Completed - Copd Clinical Trials

Arterial and End-Tidal CO2 Gradient as a Mortality Predictor in Critical Care Patients

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

Scoring systems (SOFA, APACHE-II etc.) are used to estimate the mortality rates of patients treated in the intensive care unit. . In the scoring systems used, the disfunction level of the organs of the patients is measured. Blood gas analysis is routinely performed in patients whom intubated in the intensive care unit and receiving mechanical ventilation support, and the patient's treatment is optimized according to the results of the examination. The patient's mechanical ventilation settings are regulated by analyzing the Partial Arterial Carbondioxide (paCO2) value in the patient's blood gas result. The difference between the paCO2 value in the blood gas and the End-tidal Carbondioxide (EtCO2) value measured in the mechanical ventilator is 3-5mmHg in normal healthy people, while this difference is seen more in critical care patients. In critically ill patients in the intensive care unit, there is a greater increase in the difference between paCO2 and ETCO2 in cases where mortality is high, such as global perfusion disorder, shock situations, and massive pulmonary embolism, etc. In this study, it was planned to investigate the use of the difference between the paCO2 value in the blood gas taken from the patient and the ETCO2 value measured in the mechanical ventilator to predict the mortality rate of the patient.

NCT ID: NCT05333042 Completed - Pulmonary Embolism Clinical Trials

External Validation of a Deep Learning Based Model for Pulmonary Embolism Detection on Chest CT Scans

Start date: April 1, 2022
Phase:
Study type: Observational

The scope of this study is the external validation of an explainable deep learning-based classifier for the diagnosis and detection of pulmonary embolism in computed tomography pulmonary angiography (CTPA) and contrast enhanced CT scans.

NCT ID: NCT05327036 Recruiting - Clinical trials for Umbilical Artery Embolism,Single Umbilical Artery,Pregnancy Outcome

The Effect of Single Umbilical Artery Caused by Umbilical Artery Embolism on Pregnancy Outcome

Start date: January 1, 2022
Phase:
Study type: Observational

To investigate the relationship between single umbilical artery caused by umbilical artery embolism and pregnancy outcome , and to provide evidence-based evidence for peripartum health care of pregnant women with umbilical artery embolism.

NCT ID: NCT05318092 Completed - Pulmonary Embolism Clinical Trials

Evaluating the Safety and Efficacy of the AlphaVac Multipurpose Mechanical Aspiration (MMA) F1885 PE for Treatment of Acute Pulmonary Embolism

APEX-AV
Start date: October 19, 2022
Phase: N/A
Study type: Interventional

To evaluate the safety and effectiveness of percutaneous mechanical aspiration thrombectomy using the AlphaVac Multipurpose Mechanical Aspiration (MMA) F1885 PE in a prospective trial of patients with acute intermediate-risk pulmonary embolism (PE).

NCT ID: NCT05273762 Recruiting - Pulmonary Embolism Clinical Trials

Treatment of Low-Risk Submassive Pulmonary Embolism With FlowTriever

Start date: January 25, 2022
Phase: N/A
Study type: Interventional

This study is focused on investigating the efficacy and safety of the FlowTriever device to treat low-risk submassive pulmonary embolism.

NCT ID: NCT05264168 Completed - Pulmonary Embolism Clinical Trials

Prediction of the COBRRA VTE Anticoagulant Trial in Healthcare Claims Data

Start date: May 3, 2021
Phase:
Study type: Observational

Investigators are building an empirical evidence base for real world data through large-scale replication of randomized controlled trials. The investigators' goal is to understand for what types of clinical questions real world data analyses can be conducted with confidence and how to implement such studies.

NCT ID: NCT05263024 Not yet recruiting - Atrial Fibrillation Clinical Trials

Study on the Significance of Auricular Clip in Prevention and Treatment of Valvular Heart Disease Atrial Thrombosis

Start date: February 21, 2022
Phase:
Study type: Observational

To evaluate the safety and clinical efficacy of left atrial appendage in the prevention of thrombus in patients with valvular heart disease, to improve the product according to clinical conditions, to achieve clinically accurate treatment, and to establish the heart valve, the usefulness and universality of Warfarin's anticoagulant model were verified by the specimen library

NCT ID: NCT05226416 Completed - Stroke Clinical Trials

Analysis of Health Status of Сomorbid Adult Patients With COVID-19 Hospitalised in Fourth Wave of SARS-CoV-2 Infection

ACTIV4
Start date: February 21, 2022
Phase:
Study type: Observational [Patient Registry]

Depersonalized multi-centered registry initiated to analyze dynamics of non-infectious diseases after SARS-CoV-2 infection in population of Eurasian adult patients.