1 Embryo Will be Biopsied and 1 Embryo is Not Clinical Trial
Official title:
Evaluation of the Impact of Embryo Biopsy on the Reproductive Potential of Embryos Undergoing IVF
To assess the impact of embryo biopsy on the reproductive potential of human embryos.
This study will recruit patients from the NY/NJ/CT/eastern PA area only.
All patients will undergo an in vitro fertilization (IVF) cycle with hormonal stimulation
and an egg retrieval procedure as deemed appropriate for their diagnosis. Following biopsy,
the embryos will be transferred. There will be no delay in the time of transfer as no cells
will be analyzed prior to transfer.
On day 3 or day 5 of embryo development, all patients will undergo a two (2) embryo
transfer. The embryos selected for transfer will be the 2 morphologically best of the embryo
cohort. Once selected for transfer, the embryos will be randomized so that one will be
biopsied and the other will be transferred without undergoing biopsy. The embryo randomized
to biopsy will have a single cell biopsied.
Following delivery, buccal swabs will be collected from infants.
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Time Perspective: Prospective