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Dry Eye clinical trials

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NCT ID: NCT04105842 Completed - Dry Eye Clinical Trials

Refitting Daily Disposable Contact Lens Wearers With Dry Eye Disease With A Different Daily Disposable Lens Type

CORGI
Start date: September 23, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to refit habitual wearers of daily disposable contact lenses who currently experience symptoms of dry eye and discomfort during lens wear with a different type of daily disposable contact lens. Ocular signs and symptoms of dry eye will be assessed following the guidelines outlined by the Tear Film and Ocular Surface Society (TFOS) in the Dry Eye Workshop II (DEWS II). The performance of the habitual contact lenses and the study lenses will be determined using different optometric assessments. Study lenses will be worn for one month following a daily disposable wear schedule.

NCT ID: NCT04100031 Completed - Cataract Clinical Trials

Efficacy of an Ocular Bandage Contact Lens for the Treatment of Dry Eye After Cataract Surgery

Start date: September 1, 2018
Phase: N/A
Study type: Interventional

To study the efficacy of an ocular bandage contact lens for the treatment of dry eye after cataract surgery

NCT ID: NCT04093037 Completed - Dry Eye Clinical Trials

Analysis of the Diagnostic Performance of LacryDiag, a New Analyzer of the Ocular Surface in the Dry Eye

LACRYMOSA
Start date: November 14, 2019
Phase: N/A
Study type: Interventional

LacryDiag is a new Conformity European (CE) marked diagnostic imaging device devoted to the analysis of the ocular surface. It is an "all in one" device that provides 4 data: non-invasive break-up time (Non-Invasive Break-Up-Time (NIBUT) without fluorescein eye drop); height of the Tear Meniscus (TM); an infrared image of the meibomian glands; a picture of the lacrimal film by interferometry. it's performance will be compare between in diagnosing dry eye syndrome with the standard clinical evaluation, in 80 patients suffering from dry eye diseases and followed at the consultation of the Ophthalmology department of the University Hospital of Saint-Etienne.

NCT ID: NCT04092907 Completed - Dry Eye Clinical Trials

A Study Evaluating the Efficacy and Safety on Moderate to Severe Dry Eye

Start date: March 22, 2019
Phase: Phase 2
Study type: Interventional

The purpose of this study is to compare the efficacy and safety of HBM9036 Ophthalmic Solution versus placebo in the treatment of dry eye

NCT ID: NCT04081610 Completed - Dry Eye Clinical Trials

Clinical Trial to Evaluate the Safety and Tolerability of Lagricel® Ofteno Multi-dose Ophthalmic Solution

PRO-037
Start date: September 9, 2019
Phase: Phase 1
Study type: Interventional

Study design: Phase I clinical trial, single-center, controlled, parallel group, open, randomized. Number of subjects: n = 34 evaluable subjects, 17 evaluable subjects per group (both eyes). Estimated duration of the study: 5 months Therapeutic indication: Eye lubricant Use: Dry Eye Objective:To evaluate the safety and tolerability of Lagricel® Ofteno multidose manufactured by Laboratorios Sophia on the ocular surface of clinically healthy subjects. Hypothesis: H0 = Lagricel® Ofteno multidose ophthalmic solution has a safety and tolerability profile similar to Lagricel® Ofteno single dose in healthy subjects. H1 = Lagricel® Ofteno multidose ophthalmic solution has a different safety and tolerability profile than Lagricel® Ofteno single dose in healthy subjects. Main inclusion criteria: Clinically healthy subjects

NCT ID: NCT04063735 Completed - Dry Eye Clinical Trials

Alleviating Effects Against Dry Eye by Oral Intake of Cordyceps Cicadae Mycelia

Start date: December 1, 2016
Phase: N/A
Study type: Interventional

Cordyceps cicadae mycelia was tested for amelioration of dry eye symptoms through dietary supplementation. Its efficacy in relief of human dry eye status was assessed by randomized, double-blinded tests, including multiple assessments. The results were compared between the placebo group and the experimental group.

NCT ID: NCT04043949 Completed - Dry Eye Clinical Trials

The Influences of Dry Eye Disease on Optical Quality

Start date: July 1, 2017
Phase:
Study type: Observational

DED could result in visual disturbance and damage optical quality. We aimed to evaluate the influences of dry eye disease (DED) on optical quality and their correlations.

NCT ID: NCT04022382 Completed - Dry Eye Clinical Trials

A Study to Evaluate the Safety and Effectiveness Assessments of Restylane-Defyne for Punctual Occlusion

Start date: July 18, 2019
Phase: N/A
Study type: Interventional

A study which participants with mild to moderate dry eye disease will have a punctum of one eye injected with 0.1ml Restylane Defyne and the other eye injected with 0.2ml Restylane Defyne. Participants will be evaluated over four visits.

NCT ID: NCT03992482 Completed - Dry Eye Clinical Trials

IVIG-eye Drops Treatment for Dry Eye Disease

Start date: May 1, 2019
Phase: Phase 1/Phase 2
Study type: Interventional

The main objective of this study is to establish whether patients with Dry Eye Disease are able to safely tolerate receiving Intravenous Immunoglobulin (IVIG) eye drops two times a day for eight weeks (primary 'safety and tolerability' objective). The exploratory objective is to investigate the preliminary efficacy of the use of IVIG eye drops in treating Dry Eye Disease (exploratory efficacy objective) to estimate the effectiveness of the trial intervention and collecting data to inform the design of a future definitive trial. This will be a Randomized controlled trial, in which a total of 28 subjects will be enrolled at 1 clinical site. Subjects will be randomly assigned to one of two groups (#1, #2), with 14 subjects per group. One group will be given placebo (Normal saline eye drops) and the other group will be given eye drops containing the study drug (IVIG).

NCT ID: NCT03987230 Completed - Dry Eye Clinical Trials

Comfort Associated With The Use Of Eyelid Cleansing Products Available For The Management Of Demodex Folliculorum

SPANIEL
Start date: May 29, 2019
Phase: N/A
Study type: Interventional

This aim of this study to quantify the subjective ocular awareness of different eyelid cleansing wipes available for the management of Demodex folliculorum.