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NCT ID: NCT04888273 Completed - Eating Disorders Clinical Trials

Assessing the Feasibility of an Intervention for Youth and Parents Transitioning to Adult Eating Disorder Services

Start date: May 15, 2021
Phase: N/A
Study type: Interventional

Teenagers with eating disorders often experience a disruption in care upon turning 18. At this age, they are no longer eligible to receive pediatric treatment but are also not yet set up with the appropriate adult services. There are currently no supports in place to help youth with eating disorders and their families during this transition from child to adult care. In this project, the investigators will be implementing an intervention designed to improve this transition experience; it will include peer support, parent education, a meeting with the child and adult care providers, contact with the family doctor, and a written guide about the transition. Among 10 adolescent-parent pairs leaving McMaster Children's Hospital to adult programs in Hamilton, Ontario, the investigators will assess how feasible the intervention is to implement, how feasible the chosen measures are, participants' experience of the intervention, how many adolescents actually transition to adult care, as well as a few adolescent and parent outcomes, such as how prepared the teen feels or what the parents' needs are.

NCT ID: NCT04878523 Completed - Skin Condition Clinical Trials

Investigation of the Efficacies of Multi Berries Juice on Anti Oxidant Effect and Improvement of Skin Conditions

Start date: November 9, 2020
Phase: N/A
Study type: Interventional

To assess multi berries juice on anti-oxidant effect and skin condition improvement

NCT ID: NCT04877158 Completed - Anorexia Nervosa Clinical Trials

Pilot Intervention for Social Biases in Eating Disorders

SBPI
Start date: January 31, 2018
Phase: N/A
Study type: Interventional

Both behavioral, psychological, and cognitive differences related to social cognitive function have been related to illness-state in eating disorders, but interventions that directly target these problems are limited. This pilot intervention explores whether a brief art-therapy team-building intervention coupled with psychoeducation about social behavior can change self-concept or clinical symptoms in patients with eating disorders. Participants will complete pre-treatment assessments related to social behaviors and clinical symptoms, attend four two-hour group sessions, and provide two follow-up post-treatment assessments at 1-4 weeks after the treatment and 3-5 months later. Comparisons between the pre-intervention data and the first follow-up will be the primary outcome measures. The primary hypotheses are that participants will show increases in self-esteem and positive self-attributions and decreases in eating disorder symptoms after the intervention. The secondary hypothesis is that other clinical symptoms (depression, anxiety) will be improved after the intervention. Feedback from participants about their experience with the study will assess perceived benefits as well as acquisition of the psychoeducation targets.

NCT ID: NCT04874974 Completed - Schizophrenia Clinical Trials

Feasibility of a Novel Process-based Treatment for Patients With Psychosis

PROBAS
Start date: May 10, 2021
Phase: N/A
Study type: Interventional

The purpose of this single-arm feasibility study is to develop and pilot test a novel process-based and modular group therapy approach for patients with acute psychotic symptoms in an inpatient setting.

NCT ID: NCT04870710 Completed - Schizophrenia Clinical Trials

Feasibility Electrical Stimulation Study for Visual Hallucinations

Start date: October 1, 2020
Phase: N/A
Study type: Interventional

The visual system has increasingly been recognized as an important site of injury in patients with schizophrenia and other psychoses. Visual system alterations manifest as visual perceptual aberrations, deficits in visual processing, and visual hallucinations. These visual symptoms are associated with worse symptoms, poorer outcome and resistance to treatment. A recent study using brain lesion mapping of visual hallucinations and identified a causal location in the part of the brain that processes visual information (visual cortex). The association between visual cortex activation and visual hallucinations suggests that this region could be targeted using noninvasive brain stimulation. Two case studies have found that brain stimulation to the visual cortex improved visual hallucinations in treatment resistant patients with psychosis. While promising it is unclear whether these symptom reductions resulted from activity changes in the visual cortex or not. Here we aim to answer the question whether noninvasive brain stimulation when optimally targeted to the visual cortex can improve brain activity, visual processing and visual hallucinations. The knowledge gained from this study will contribute to the field of vision by providing a marker for clinical response and by personalizing treatment for patients with psychosis suffering from visual symptoms. This grant will allow us to set the foundation for a larger more targeted study utilizing noninvasive brain stimulation to improve visual symptoms in patients with psychosis.

NCT ID: NCT04868409 Completed - Clinical trials for Intubation Conditions

Intubating Conditions During Rapid Sequence Induction in Elderly With Either Suxamethonium 1.0 mg/kg or Rocuronium 1.0 mg/kg

Start date: August 12, 2021
Phase: Phase 4
Study type: Interventional

The aim of this study is to determine the proportion of excellent tracheal intubation conditions at 60 seconds after administration of either rocuronium 1.0 mg/kg or suxamethonium 1 mg/kg in patients with age ≥ 80 years during rapid sequence induction.

NCT ID: NCT04867044 Completed - Fibromyalgia Clinical Trials

Prevalence of Temporomandibular Disorders in Patients With Fibromyalgia Syndrome

Start date: May 1, 2021
Phase:
Study type: Observational [Patient Registry]

One Hundred Fifty woman patients diagnosed with fibromyalgia according to the American College of Rheumatology 2010 diagnostic criteria and 150 healthy woman volunteers will be included.Demographic data (age, gender, height, weight, marital status, education level) and duration of fibromyalgia diagnosis will be recorded. Patients will be evaluated according to the Diagnostic Criteria for Temporomandibular Disorders: Assessment Instruments (DCTMD: AI ). Patients will be evaluated by Diagnostic Criteria for Temporomandibular Disorders: Temporomandibular Disorders (TMD) Pain Screener, Symptom questionnaire, Clinical Examination Form from Assessment Instruments Axis I. Pain Drawing, Graded Chronic Pain (version 2), Jaw Functional Limitation Scale-8 (JFLS-8), Patient Health Questionnaire (PHQ-4), Oral Behaviors Checklist will be applied within the scope of Axis II.

NCT ID: NCT04866849 Completed - Clinical trials for Temporomandibular Disorder

The Effect of Bruxism on Temporomandibular Disorders

Start date: June 15, 2021
Phase:
Study type: Observational [Patient Registry]

This case-control study consists of 120 participants aged between 18 and 65 years. Case group included 60 patients with bruxism who presented to physical medicine and rehabilitation outpatient clinic between May 2021 and August 2021. Control group included 60 healthy participant. Patients who had temporomandibular region surgery, congenital teporomandibular joint pathologies, and previous temporomandibular region trauma were also excluded. Assessments including age, gender, body mass index (BMI), education level, and symptom duration were recorded. Patients was evaluated according to the Diagnostic Criteria for Temporomandibular Disorders: Assessment Instruments. Patients was evaluated by Diagnostic Criteria for Temporomandibular Disorders: TMD Pain Screener, Symptom questionnaire, Clinical Examination Form from Assessment Instruments Axis I. Pain Drawing, Graded Chronic Pain (version 2), Jaw Functional Limitation Scale-8 (JFLS-8), Patient Health Questionnaire (PHQ-4) , Oral Behaviors Checklist were applied within the scope of Axis II.

NCT ID: NCT04866511 Completed - Domestic Violence Clinical Trials

Video NET With CYP Who Witnessed Domestic Violence

Start date: April 13, 2021
Phase: N/A
Study type: Interventional

Research suggests that children and young people (CYP) who witness domestic violence are susceptible to develop Post-traumatic stress (PTS). As their traumatic experiences are often repeated and prolonged, these CYP are likely to present with 'complex trauma' presentations, which also include other difficulties such as depressive symptoms and problems in functioning. This study aims to investigate whether Narrative Exposure Therapy (NET) delivered via videoconferencing can be effective, feasible, and acceptable for CYP who witnessed domestic violence. NET is a brief, evidence-based intervention for complex trauma which has been adapted for CYP. The study will use a 'single case study series' design and look at whether NET can impact on PTS, psychological distress, and functioning. It will also look at the processes of change within NET and participants' experience of the therapy. Young people aged 12-17 who are experiencing PTS after exposure to domestic violence will be recruited from the waiting lists of Child and Adolescent Mental Health Services in Lincolnshire Partnership NHS Foundation Trust and Nottinghamshire Healthcare NHS Foundation Trust. Up to six participants will receive six to ten weekly video sessions and the changes in the outcomes will be explored before, during and after NET. Finally, participants will be interviewed about their experiences. The study is part of a Doctorate in Clinical Psychology programme and funded by Health Education England. Potential benefits include investigating NET with a new group, contributing to the research on complex trauma interventions for CYP, and providing insights on the effectiveness and acceptability of therapies via video.

NCT ID: NCT04854707 Completed - IVF Clinical Trials

An Observational Study of Follitropin Alpha Biosimilar: the Real-world Data

Start date: January 12, 2020
Phase:
Study type: Observational

Aim to investigate the efficacy of follitropin alpha biosimilar therapy (Primapur®) in nonselected real-world population.