Analysis of FAZ in Diabetic Retinopathy Using OCT Angiography

Status Not yet recruiting

Clinical Trial Summary

Study and assessment of characteristic changes in foveal avascular zone during different stages of diabetic retinopathy using OCTA.

Clinical Trial Description

OCTA is superior to other retinal imaging techniques like fluorescein angiography(FA) as it does not require dye injection, Intravenous dye injection is time consuming and can have adverse side effects. Furthermore, the edges of the capillaries can become blurred due to dye leakage and imaging of the retina can only be 2D when using FA. OCTA provides both structural and functional (i.e. blood flow) information in tandem. The "corresponding" OCT b-scans can be co-registered with the simultaneous OCT angiograms so the operator is able to scroll through the OCT angiogram like a cube scan. As a result, the precise location of pathology can be viewed on the corresponding OCT b-scans. This makes OCTA a better tool when detecting the exact location of a retinal pathology. In diabetic retinopathy OCTA can show choriocapillaris abnormalities and/or retinal microvascular abnormalities such as microaneurysms, vascular remodeling adjacent to the foveal avascular zone (FAZ), enlarged FAZ, and capillary tortuosity and dilation through different stages. OCTA can show smaller vascular changes not detectable by FA. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05140304
Study type	Interventional
Source	Assiut University
Contact	Kareem Md Ali, Resident
Phone	+201091319590
Email	kmasms2712@gmail.com
Status	Not yet recruiting
Phase	N/A
Start date	November 30, 2021
Completion date	November 2022

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