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Diabetic Retinopathy clinical trials

View clinical trials related to Diabetic Retinopathy.

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NCT ID: NCT01478737 Completed - Clinical trials for Proliferative Diabetic Retinopathy

Intravitreal Ozurdex After Pars Plana Vitrectomy for Proliferative Diabetic Retinopathy

Start date: November 2011
Phase: Phase 2
Study type: Interventional

To evaluate if intravitreal Ozurdex can reduce the incidence of recurrent vitreous hemorrhage after primary pars plana vitrectomy (PPV) in patients with proliferative diabetic retinopathy (PDRP).

NCT ID: NCT01476449 Completed - Clinical trials for Diabetic Retinopathy

Dosing Study of Ranibizumab for Diabetic Retinal and Macular Edema

Start date: November 2011
Phase: Phase 2
Study type: Interventional

This study is to see whether treating diabetic retinal swelling with ranibizumab injections into the eye monthly is better than treating diabetic retinal swelling with ranibizumab injections into the eye less frequently.

NCT ID: NCT01445899 Completed - Clinical trials for Diabetic Retinopathy

PF-04523655 Dose Escalation Study, and Evaluation of PF-04523655 With/Without Ranibizumab in Diabetic Macular Edema (DME)

MATISSE
Start date: February 2012
Phase: Phase 2
Study type: Interventional

This is a two-part study. The first part (Stratum I) is an open-label, dose escalation, safety, tolerability and pharmacokinetic study, where active study drug (PF-04523655) will be given to all patients who participate. Stratum I will determine the maximum tolerated dose and any dose-limiting toxicities. The second part (Stratum II) is a prospectively randomized, multi-center, double-masked, dose ranging study evaluating the efficacy and safety of PF-04523655 alone and in combination with ranibizumab versus ranibizumab alone in patients with DME.

NCT ID: NCT01440660 Completed - Clinical trials for Diabetic Retinopathy

Phenotypes of Nonproliferative Diabetic Retinopathy in DM 2 Patients Identified by OCT, CFP, RLA and mfERG (DIAMARKER)

Start date: January 2012
Phase: N/A
Study type: Observational

To characterise phenotypes of Non Proliferative Diabetic Retinopathy (NPDR) progression using multimodal testing/imaging procedures.

NCT ID: NCT01415037 Completed - Clinical trials for Diabetic Retinopathy

Annular Array Ultrasound in Ophthalmology

Start date: October 2011
Phase:
Study type: Observational

The objective of this research is to improve the care of ocular disease and disorders, in particular the changes in the eye associated with diabetes, by providing clinicians with dramatically improved ultrasonic images of the entire eye. The research combines advanced high-frequency, high-resolution ultrasonic annular arrays transducers with new processing techniques designed to overcome several limits that have been reached with conventional high frequency ultrasound systems. The investigators propose that diagnosis of eye diseases using annular arrays can be more effective than the conventional ultrasound images by at least 50%; i.e., that for every 2 posterior vitreous detachments detected conventionally, 3 will be detected with the annular arrays.

NCT ID: NCT01383772 Completed - Clinical trials for Proliferative Diabetic Retinopathy

Retinal Laser by Multi-spot Photocoagulator and Driving Eligibility

Start date: June 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the risk of failing the visual field criteria to hold a driving license following retinal laser treatment delivered with a multi-spot photocoagulator.

NCT ID: NCT01373476 Completed - Clinical trials for Diabetic Retinopathy

Multicentre, Randomized, Controlled Trial of Qideng Mingmu Capsule in The Treatment of Diabetic Retinopathy

Start date: March 2011
Phase: Phase 2
Study type: Interventional

Objectives of study: To preliminarily evaluate the efficacy and safety of Qideng Mingmu Capsule in the treatment of patients with diabetic retinopathy (deficiency of Qi-Yin syndrome, blood stasis syndrome), to discuss the appropriate dose and period of treatment.

NCT ID: NCT01364129 Completed - Clinical trials for Diabetic Retinopathy

The Comparative Effectiveness of Telemedicine to Detect Diabetic Retinopathy

Start date: August 2006
Phase: N/A
Study type: Interventional

This project aims to: 1) evaluate the long-term effectiveness of telemedicine to detect diabetic retinopathy when compared to traditional surveillance methods, 2) identify the health belief factors related to adherence with annual diabetic eye exams, and 3) determine the cost-effectiveness of the telemedicine system from the perspective of the community clinic, the third-party payer, and the individual patient.

NCT ID: NCT01323348 Completed - Diabetes Clinical Trials

Effect of Diabetes Education During Retinal Ophthalmology Visits on Diabetes Control

Start date: October 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess whether glycemic control (assessed with HbA1c measurement) in individuals with type 1 or type 2 diabetes can be improved with a point-of-care measurement of HbA1c in the ophthalmologist's office combined with a personalized risk assessment for diabetic retinopathy and other complications of diabetes.

NCT ID: NCT01319487 Completed - Clinical trials for Diabetic Macular Edema

Safety and Efficacy Study of Topical Administration of FOV2304 (High Dose or Low Dose) for the Treatment of Center-involving Clinically Significant Macular Edema Associated With Diabetic Retinopathy

Start date: May 2011
Phase: Phase 2
Study type: Interventional

The purpose of the study is to determine whether concentrations of FOV2304 (high dose or low dose) administered in the eye are more effective than placebo in treating patients with diabetic macular edema, following 12 weeks of treatment.