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Diabetic Foot clinical trials

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NCT ID: NCT03717233 Completed - Diabetic Foot Ulcer Clinical Trials

Assistive ExoSkeletons to Enable Wearable Rehabilitation Robotics

Start date: October 18, 2018
Phase: N/A
Study type: Interventional

Study will evaluate the use of lower-limb assistive exo-skeletons worn on the ankle and foot. Participants will wear the exo-skeletons and walk in a safe environment. Measurements will be taken to determine how the exo-skeletons affect the pressure on the feet of people with diabetic foot ulcer and how they walk.

NCT ID: NCT03716141 Completed - Diabetic Foot Ulcer Clinical Trials

Autologous Platelets Rich Plasma (APRP) Treatment Vs Saline Dressing for the Management of Diabetic Foot Ulcer

APRP
Start date: January 1, 2018
Phase: N/A
Study type: Interventional

The aim of this study is to compare between the platelet rich plasma and normal saline dressing in the healing diabetic foot ulcers. It will be a randomized controlled trial.

NCT ID: NCT03700580 Completed - Diabetic Foot Clinical Trials

Clinical Trial Using the Proteolytic Fraction P1G10 From V. Cundinamarcensis to Heal Diabetic Foot Ulcer

P1G10
Start date: August 15, 2012
Phase: Phase 2
Study type: Interventional

The aim of the study was to investigate the role of the proteolytic fraction from Vasconcellea cundinamarcensis, designated as P1G10, on healing of chronic foot ulcers in neuropathic patients diagnosed with diabetes type 2. Fifty patients were enrolled in a prospective, randomized, double-blind trial, to verify the efficacy and safety of a topical dressing containing 0.1% P1G10, versus a Hydrogel (positive control) protocol currently applied at the Health Center to treat this condition. Upon completion of the intervention, the outcome evaluated the number of patients attaining full epithelization (100%), or at least 80% healing in both arms (P1G10 versus Hydrogel). Statistical analysis compared the endpoint data on each group to assess the significance of differences.

NCT ID: NCT03670225 Completed - Diabetic Foot Ulcer Clinical Trials

Evaluating Clinical Acceptance of a NPWT Wound Care System

Start date: October 16, 2018
Phase: N/A
Study type: Interventional

Determine if use of the Medela Invia Motion NPWT system supports acceptable progress towards the goal of therapy when treating patients with a variety of wound types during the evaluation period.

NCT ID: NCT03662997 Completed - Diabetic Foot Ulcer Clinical Trials

Clinical Study to Compare 3 Multi-Layered Foam Dressings for the Management of Chronic Wounds

Start date: March 19, 2019
Phase: N/A
Study type: Interventional

A prospective, randomized, controlled clinical trial (RCT) using a cross-over (repeated measures) design to evaluate safety and efficacy of three foam wound dressings in the local management of chronic wounds.

NCT ID: NCT03649243 Completed - Clinical trials for Diabetes Mellitus, Type 2

Propolis as Adjuvant in the Healing of Human Diabetic Foot Wounds

Start date: October 2015
Phase:
Study type: Observational [Patient Registry]

The general objective of the project is "To evaluate the effect of the administration of propolis extract as a coadjuvant in the treatment of diabetic foot ulcers in patients receiving cures in the Specialties Polyclinic of the Regional Hospital of Talca, Maule Region", which will be used Propolis produced in the area, (Laboratorios Rotterdam Ltda.) used in topical form. It has been described that among the benefits produced by Propolis, is its anti-inflammatory, antioxidant effect and that the topical application of it is well tolerated, improving the healing of human diabetic foot ulcer.

NCT ID: NCT03636867 Completed - Diabetes Mellitus Clinical Trials

Laboratory, Cellular and Molecular Determinants of Clinical Success in Diabetic Patients With Critical Limb Ischemia

ECAD-CLI
Start date: August 7, 2018
Phase:
Study type: Observational [Patient Registry]

The ECAD-CLI is an investigator-driven, prospective, single-center study. The aim of the study is to prospectively collect clinical, laboratory, angiographic, cellular and molecular variables related to prognosis and outcome in patients with diabetes mellitus and critical limb ischemia.

NCT ID: NCT03624023 Completed - Diabetic Foot Ulcer Clinical Trials

TWB-103 for Treating Lower Limb Ulcers on Patients With DM

Start date: December 19, 2019
Phase: Phase 1/Phase 2
Study type: Interventional

Primary Objective: To assess the safety profile of TWB-103 administered to subjects with diabetic lower limb ulcers Secondary Objective: To explore the efficacy of TWB-103 administered to subjects with diabetic lower limb ulcers

NCT ID: NCT03615807 Completed - Diabetic Foot Clinical Trials

Less Infections for the Diabetic Foot

Start date: February 16, 2017
Phase: N/A
Study type: Interventional

This is a randomized, unblinded, single-centre study. After eventual surgical debridement (not amputation), patients will be randomized to receive 1 of 2 targeted antibiotic regimens, in the ratio 1:1. For diabetic toe osteomyelitis, the patients will be randomized between a 3 and a 6 week's arm, for soft tissue infections between 10 and 20 days. The final assessments used in the primary efficacy analysis will be obtained at the test-of-cure (TOC) visit approximately 60 days after treatment is stopped.

NCT ID: NCT03615755 Completed - Diabetic Foot Ulcer Clinical Trials

Short Duration Hyperbaric Oxygen Therapy to Improve HbA1c, Leukocyte, and Serum Creatinine

Start date: December 27, 2016
Phase: N/A
Study type: Interventional

The investigators want to evaluate the short duration HBOT can improve glycohemoglobin (HbA1c) levels, leukocyte count, and serum creatinine levels in patients with DFU (diabetic foot ulcer) Wagner 3-4.