View clinical trials related to Diabetic Foot.
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The aim of this study is to investigate efficiency of applying of adipose-derived mesenchymal stem cells (ADSC) in treatment of chronic wounds in diabetic foot syndrome.
This study aims to evaluate the effectiveness of NATROX™ Topical Oxygen Wound Therapy for subjects with non-healing foot ulceration. Subjects will be treated with standard care for 4 weeks. If the wound is not reduced by more than 40%, NATROX™ will be applied for the next 12 weeks. Throughout the study period, wound measurements will be taken to measure wound reduction.
A clinical study at the Baylor College of Medicine, Division of Vascular Surgery and Endovascular Therapy, is being proposed to test the efficacy of a novel electrical stimulation platform named the Tennant Biomodulator designed by AVAZZIA to accelerate wound healing, relieve pain and improve mobility in patients with diabetic foot ulcers.
The Healing effects of Honey and Hydrogel Products on the Diabetic Foot. Abstract: Diabetes mellitus epidemiology is increasing dramatically affecting high numbers of the world's population, one of the highest risk consequences is diabetic foot and which might lead to leg amputation causing a permanent disability for the patient. Several studies had been conducted on the options available to treat diabetic foot ulcer, Honey products and Hydrogel stands out as an effective topical treatment for the foot ulceration. This study discusses the effectivity rate of these products and compares it with the classical methods followed to treat DF using topical and systematic antibiotics. Hence; our research raises the following questions: 1. What is the effect of Honey and Hydrogel on the foot anatomy and physiology of DF patients? 2. Could the investigators introduce a new protocol to treat DF using Honey and Hydrogel products? Aiming to achieve the following objects: 1. To provide a new protocol to improve the anatomy and physiology of DF. 2. To compare the efficacy of combined Hydrogel and Honey products on the diabetic foot ulcer. Reaching there the investigators are expecting to: 1. To compare the healing time between the patients treated with hydrogel/honey products and the control treatment patients. 2. To compare Lab parameters improvements between the patients treated with hydrogel/honey products and the control treatment patients. 3. To compare neurological improvements between the patients treated with hydrogel/honey products and the control treatment patients. 4. To compare the anatomical improvements between the patients treated with hydrogel/honey products and the control treatment patients. In order to provide a clear estimation for the safety and effectivity profile for each treatment method. Based on that the investigators are conducting using single blinded randomized clinical trial Suggesting the following Hypothesis: Treatment using topical MediHoney gel and/or Hydrogel together separately in association with empiric antibiotic regimens have a higher success rate comparing with treatment using topical and empiric antibiotic. A total of 120 DM patients from Outpatients DM type 2 will be included in this study, following up at diabetic foot center Al-Qaseem Saudi Arabia. Patients will be divided into 4 groups: 1. st group will be treated with topical Medihoney product and empiric antibiotic. 2. nd group will be treated with topical Hydrogel (purloin) gel and empiric antibiotic. 3. rd group will be treated with a combination of Medihoney gel and Hydrogel (purloin) gel and empiric antibiotic. The 4th group will be treated with a combination of systematic and topical fucidin 1% antibiotic this group will be a controlled group. Based on the expected results the investigators are estimating that this study will raise the awareness of both health care personnel and the diabetic patients about this condition. It is expected to provide a clear efficacy estimation for each treatment method followed, facilitating the choice of treatment for physicians.
The purpose of this study, is to determine whether daily supplements of vitamin D improves wound healing in diabetic patients with chronic foot ulcers.
The study evaluates the efficacy of Low-level laser therapy on ulcer healing in patients with diabetic foot ulcer. Half the patients are randomized to receive Low-level laser therapy and a half to recieve the placebo (LED).
As the global mortality rate decreases for diabetics patients, further explorations and datas are needed about the specific population of diabetics patients suffering a Diabetic Foot Ulcer (DFU). This study investigates the 5 years mortality rate in patients with a diabetic foot ulcer occurring in 2010.
Despite the prominence of diabetes prevalence (more than 8% of the world population in 2012) and its expected increase in the next 15 years, Charcot foot remains a widely unknown diabetes complication. At this day, there is no national guidelines about diagnosis and treatment of this complication, which is known to alter life quality and to increase risk of foot ulceration and mortality in diabetics. Through this descriptive multicentric study, we will investigate the Charcot foot cares in diabetic-foot centers in France and Belgium.
The investigators plan to evaluate healing in a cohort of patients with chronic wounds (n=40) that receive optimal treatment including serial wound debridement and off-loading with total contact casts or a boot and GrafixPL PRIME. In addition, the investigators will collect data on other potential confounding factors that could affect healing such as medications, tobacco, nutrition, comorbidities, diabetes control, infection, perfusion, and activity. Wound healing, including wound size and adverse events will be evaluated. The objective of this study is to understand the use of this product to evaluate wound healing in 40 patients.