Preventing Post-Stroke Depression

Status Completed

Clinical Trial Summary

This study will evaluate the effectiveness of both drug and non-drug treatments in preventing depression after a stroke.

Clinical Trial Description

The development of depression after a stroke is a serious condition that can have negative effects on thought, emotions, and overall daily functioning, particularly in the first year following the stroke. Evidence suggests that antidepressants may be used to prevent post-stroke depression. This study will treat nondepressed stroke patients with antidepressants or problem solving therapy (PST) to determine the most effective treatments for preventing depression.

Participants in this study will be randomly assigned to receive PST, escitalopram, or placebo (an inactive pill) for 12 months. Participants who display depressive symptoms for 2 weeks or more will be removed from the study. After 12 months, treatment will be discontinued and participants will be monitored for an additional 6 months. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00071643
Study type	Interventional
Source	University of Iowa
Contact
Status	Completed
Phase	N/A
Start date	September 2002
Completion date	November 2008

View Details

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