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Dentin Sensitivity clinical trials

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NCT ID: NCT02378129 Completed - Clinical trials for Dentin Hypersensitivity

Evaluation of Dentin Hypersensitivity Using Glass Ionomer Cements

Start date: April 2, 2014
Phase: Phase 2/Phase 3
Study type: Interventional

The aim of this randomized, double-blind, split-mouth clinical trial is to evaluate and compare the desensitizing efficacies of the resin-modified glass ionomer cement ClinproTM XT (3M ESPE, Minnesota, USA) and the conventional glass ionomer cement Vidrion R (SS White, Gloucester, UK) at 2-year follow-up.

NCT ID: NCT02371616 Completed - Dentine Sensitivity Clinical Trials

Clinical Study to Evaluate the Efficacy of Two Dentifrices for Dentine Hypersensitivity

Start date: September 29, 2014
Phase: N/A
Study type: Interventional

An 8 week clinical study to evaluate the ability of an experimental dentifrice containing calcium sodium phosphosilicate and sodium fluoride to provide relief from dentine hypersensitivity compared to a marketed dentifrice containing calcium sodium phosphosilicate and sodium monofluorophosphate.

NCT ID: NCT02316080 Completed - Clinical trials for Dentin Hypersensitivity

The Effect of Desensitizing Agents in In-home or In-office Dental Bleaching

Start date: July 2011
Phase: Phase 4
Study type: Interventional

The aim of this project is to evaluate in vitro and in vivo the effect of dental bleaching agents, carbamide peroxide 16% (T1) and hydrogen peroxide 35% (T2) together with desensitizers/remineralizer agents, Sensodyne® dentifrice (D1); experimental dentifrice with 7,5% of Biosilicate micro-particles (D2); Odontis RX® dentifrice (D3); Sorriso® dentifrice (D4); Biosilicate micro-particles paste, 1:1 (D5), Desensebilize Nano P (D6), bioglass type 45S5 paste, 1:1 (D7); GC= distilled water, in the experimental groups: T1/D1; T1/D2; T1/D3; T1/D4; T1/D5; T1/D6; T1/D7; T1/GC e T2/D1; T2/D2; T2/D3; T2/D4; T2/D5; T2/D6; T2/D7; T2/GC. In the in vitro study, microhardness and roughness measurements, and images using scanning electron microscopy (SEM) will be made on samples of bovine dental enamel and dentin (4x4x3mm; n=10 per group) before and after the treatment with the bleaching gels (T1= 14 days/ 04 hours/day; T2=single session) and the desensitizers/remineralizer agents. In the clinical study, the volunteers (n=10 per group) will be evaluated regarding dentin hypersensitivity (DH), using visual analogue scale, before the beginning of the treatments (T1 and T2) and during the next 14 days (1º, 3º, 7º, 10 º e 14º days) in which the desensitizers/remineralizer agents (there´s no control group in the clinical experiments) will be applying. Data will be analysed intra and inter-group, statistically.

NCT ID: NCT02293044 Completed - Dentin Sensitivity Clinical Trials

A Study to Evaluate the Safety and Efficacy of an Oxalate Strip on Adjacent Teeth With Dentinal Hypersensitivity

Start date: November 2014
Phase: N/A
Study type: Interventional

This study will compare the safety and effectiveness of a potassium oxalate desensitizer on adjacent teeth with dentinal hypersensitivity.

NCT ID: NCT02226562 Completed - Dentin Sensitivity Clinical Trials

Clinical Study Investigating the Efficacy of a Mouthwash in Providing Long Term Relief From Dentinal Hypersensitivity

Start date: September 2, 2014
Phase: Phase 2
Study type: Interventional

The aim of this study is to investigate the longitudinal efficacy of a potassium nitrate mouthwash formulation when used as an adjunct to brushing with a standard fluoride dentifrice for the relief of dentinal hypersensitivity (DH) compared to brushing with a standard fluoride dentifrice alone. This will be a single centre, eight week, randomised, examiner blind, two treatment arm, parallel design, stratified (by maximum baseline Schiff Sensitivity Score of the two selected test teeth) study in participants with at least two sensitive teeth that meet all the criteria at the Screening and Baseline visit. Participants will be assessed at Baseline, and at four and eight weeks to monitor clinical efficacy and safety.

NCT ID: NCT02221349 Completed - Dentin Sensitivity Clinical Trials

A Clinical Study of Two Dentinal Hypersensitivity Treatments Used With Normal Oral Hygiene

Start date: August 2014
Phase: N/A
Study type: Interventional

This study will compare the safety and effectiveness of normal oral hygiene with two different marketed dentifrices, on longer term dentinal hypersensitivity response following use of potassium oxalate desensitizers.

NCT ID: NCT02192307 Completed - Dentin Sensitivity Clinical Trials

Effectiveness of Two Water-Based Potassium Oxalate Desensitizers

Start date: July 2014
Phase: N/A
Study type: Interventional

This study will compare the safety and effectiveness of two water-based potassium oxalate desensitizers on existing dentinal hypersensitivity.

NCT ID: NCT02189382 Completed - Dentin Sensitivity Clinical Trials

Evaluation of the Safety and Efficacy of an Oxalate Gel or Negative Control on Dentinal Hypersensitivity

Start date: June 2014
Phase: N/A
Study type: Interventional

This study will compare the safety and effectiveness of a potassium oxalate desensitizer or negative control on dentinal hypersensitivity.

NCT ID: NCT02152826 Completed - Dentin Sensitivity Clinical Trials

Effectiveness of Two Water-Based Potassium Oxalate Desensitizers on Dental Hypersensitivity

Start date: March 2014
Phase: N/A
Study type: Interventional

This study will compare the safety and effectiveness of two water-based potassium oxalate desensitizers on existing dentinal hypersensitivity.

NCT ID: NCT02128633 Completed - Dentin Sensitivity Clinical Trials

Effectiveness of a Homecare Dentin Hypersensitivity Gel

ECR
Start date: November 2009
Phase: Phase 2/Phase 3
Study type: Interventional

Aim: To evaluate the effectiveness of a desensitizing gel for topical and home use in the treatment of dentin hypersensitivity (DH) through a randomized clinical trial, double-blind, with three parallel treatment. Methods: 126 subjects were divided into three groups: placebo gel (PG), test gel (TG) (5% sodium fluoride, potassium oxalate 5%, strontium chloride 10%) and sodium fluoride gel (2% FG ). The measurement of DH was performed by a single examiner blinded by the visual analog scale (VAS) after tactile, thermal and osmotic stimuli in the Baseline, 7, 15 and 30 days.