Clinical Trials Logo

Clinical Trial Summary

The study was designed as a retrospective, parallel, two years longitudinal pilot trial. Twenty-eight patients (mean age: 48.34 ± 6.06) aged between 35 and 60 years and 66 TiUnite surfaces (Nobel Biocare Parallel Conical Connection), bone level dental implant were included in the study. The implants were divided into two different groups according to the NPIs and regular platform implants(RPIs). The mean implant lengths, plaque index(PI), gingival index(GI), periodontal pocket depth(PD), gingival recession(GR), keratinized gingival width(KGW) and bleeding on probing(BOP) values were recorded. The Student's t-test used for between-group comparison.


Clinical Trial Description

Fifty-one participants and 123 dental implants were evaluated; twenty-three participants and 49 dental implants were excluded because of the different commercial brand dental implant (AstraTech, Straumann Roxolid, Bilimplant) and declining to participate. Seventy-four TiUnite dental implants were included in the study, but 8 TiUnite surface implants placed in the anterior region were excluded. Consequently, 15 male and 13 female patients and 66 dental implants were included in the study. This randomized retrospective clinical trial was designed according to the Consolidated Standards of Reporting Trials (CONSORT) Statement guidelines. A CONSORT Flow Chart of this study was shown in Figure 118.

The assignment was performed according to the dental implant diameters to include cases in the NPI and RPI which are the test and control groups. All dental implants involved are the Nobel Biocare Parallel CC brand (Nobel Biocare, Gothenburg, Sweden) with a TiUnite surface, and it defined a regular diameter of 4.3 mm and narrow diameter of 3.75 mm. Dental implants divided into two groups according to implant diameter, the NPI group comprised 3.75 mm diameter (NP, Ø= 3.75 mm) implants, and the RPI group comprised 4.3 mm diameter (RP, Ø= 4.3mm) implants (implant lengths: 10 mm-13 mm).

Clinical Measurements The clinical measurements were recorded at follow-up sessions using a periodontal probe that was calibrated in 1 mm increments. The clinical measurements were as follows: 1) plaque index (PI); 2) gingival index (GI); 3) probing depth (PD), the distance between the gingival margin and the bottom of a pocket; 4) clinical attachment level (CAL); the distance from the neck of the implant and the bottom of the pocket; 5) bleeding on probing (BOP); 6) keratinized gingival width (KGW), the height of peri-implant keratinized mucosa; 7) gingival recession (GR), the distance between the neck of the implant and the gingival margin. The same researcher performed all clinical measurements. A calibration protocol was applied to the reliability of measurements. PI, GI, PD, CAL, GR, KGW meaurements on five patients and ten peri-implant values were assessed. Calibration was accepted when measurements were 90% similar20. All clinical measurements were recorded for four sites (mesiobuccal, distobuccal, mid-buccal, mesiopalatal, midpalatal, and distopalatal) per peri-implant region. PD and PI measurements are reliable in peri-implantitis diagnosis21.

Prosthetic complications of patients were also evaluated clinically. Veneer ceramic chipping, abutment screw loosening or fracture, implant fracture, loss of retention were recorded.

Radiographic Measurements The studies have reported that periapical radiographs taken with the parallel technique are reliable in determining the MBL changes at different follow-ups. Digital periapical radiographs of the posterior region were obtained using a parallel method at follow-up sessions. MBL measurements were provided on periapical radiographs by a software program (Mediadent Software, The Dental Imaging Company, London, England). Ten radiographic MBL measurements around peri-implant were performed twice with an interval of 3 weeks, and researcher calibration was accepted when measurements were similar as %90. MBL was measured separately from the mesial and distal parts and also which the average of the two measurements. The reference points for the assessments are the implant shoulder and the most apical end-point of the bone-implant contact point. The vertical length between these two points is defined as MBL. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04572490
Study type Observational [Patient Registry]
Source T.C. Dumlupinar Üniversitesi
Contact
Status Completed
Phase
Start date June 27, 2019
Completion date October 28, 2019

See also
  Status Clinical Trial Phase
Not yet recruiting NCT05470673 - Autogenous Demineralized Dentin Graft Combined With Injectable PRF + Metronidazole Versus Autogenous Demineralized Dentin Graft Alone for Alveolar Ridge Preservation N/A
Recruiting NCT02580721 - The Influence of Mucosal Tissue Thickness on Soft and Hard Tissue Changes Around Implants N/A
Completed NCT02515058 - Ridge Preservation Following Tooth Extraction Using Two Mineralized Cancellous Bone Allografts N/A
Enrolling by invitation NCT02209311 - Effectiveness and Safety of Method of Maxilla Alveolar Process Reconstruction Using Synthetic Tricalcium Phosphate and Autologous MMSCs Phase 1/Phase 2
Completed NCT02602223 - Comparison of Amnion Chorion Membrane vs. Dense Polytetrafluoroethylene Membrane in Ridge Preservation Procedures Phase 2
Completed NCT02255149 - A Feasibility Study for Growth Bone Vertically With Titanium Mesh and Allograft in Lower Posterior Jaw N/A
Recruiting NCT06081296 - Dimensional Changes in Alveolar Ridge Preservation N/A
Recruiting NCT05674331 - Clinical, Radiographical, Histological Evaluation and Blood Flow Analysis of Alveolar Ridge Preservation N/A
Completed NCT03944811 - Bone Height Gain Following Transcrestal Sinus Floor Elevation Using Piezoelectric Surgery Versus The Conventional Osteotome Technique N/A
Completed NCT03045458 - Associations of Alveolar Bone Loss and Interleukin-1β Levels in One and Two Stage Surgical Procedures N/A
Completed NCT05595746 - Radiological Bone Loss on Different Levels of Dental Implants N/A
Completed NCT03357705 - Effectiveness in Limiting the Need to Elevate the Maxillary Sinus N/A
Recruiting NCT05311735 - Mineralized and Partial Demineralized Dentin Graft Compared to FDBA N/A
Completed NCT05494476 - Stability of the Marginal Bone Around Subcrestal Implants N/A
Not yet recruiting NCT05536479 - Evaluation of Autogenous Stored Versus Autogenous Fresh Mineralized Dentin Graft for Alveolar Ridge Preservation N/A
Active, not recruiting NCT02275767 - Histological Evaluation of Healing Following Ridge Preservation Using a Combined Cortical/Cancellous Mineralized Freeze-Dried Bone Allograft N/A
Active, not recruiting NCT02120053 - Interest of Bone Substitute Material in Immediate Complete Denture Phase 2/Phase 3
Completed NCT01728844 - GUIDOR® Growth Factor Enhanced Bone Graft Substitute for the Treatment of Periodontal Defects 6-months Post-Surgery N/A
Terminated NCT00991965 - Localized Alveolar Ridge Augmentation With Dental Implant N/A
Terminated NCT00991432 - Localized Alveolar Ridge Augmentation With Space Maintenance Devices N/A