Clinical Trials Logo
  1. Home
  2. Dental Caries
  3. NCT02885064
  4. Details
NCT02885064 Clinical Trial

Shifts in the Oral Biofilm of Patients With Known Oral Health Risk Factors

Dental Caries Clinical Trial

Official title:
Shifts in the Oral Biofilm of Patients With Known Oral Health Risk Factors

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT02885064
Other study ID # 16-1624
Secondary ID
Status Completed
Phase
First received
Last updated
Start date August 2016
Est. completion date June 22, 2021

Study information
Verified date April 2021
Source University of North Carolina, Chapel Hill
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

This study is observational only and is intended to evaluate changes in the makeup and function of bacteria naturally present in the mouth during treatment with braces to straighten teeth.

Recruitment information / eligibility
Status Completed
Enrollment 34
Est. completion date June 22, 2021
Est. primary completion date June 22, 2021
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 8 Years to 99 Years
Eligibility Inclusion Criteria: - ASA I or II (ASA I is a healthy patient, ASA II is patient with minor systemic disease) - Patient must be receiving orthodontic treatment at the University of North Carolina School of Dentistry and not yet be in active treatment Exclusion Criteria: - Patients who have used antibacterial therapy in the past 3 months - Patients who report current smoking - ASA III or above (Patients with severe systemic diseases)

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
United States UNC School of Dentistry Chapel Hill North Carolina

Sponsors (1)
Lead Sponsor Collaborator
University of North Carolina, Chapel Hill

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Change in Shannon diversity index from Baseline to Month 6 Baseline, Month 6
Primary Change from Baseline to Month 6 in Clusters Of Orthologous Groups of proteins Baseline, Month 6
Secondary Change in gingival index Baseline, Month 6
Secondary Change in decalcification index Baseline, Month 6
See also
  Status Clinical Trial Phase
Completed NCT04127929 - Investigation of Glass Carbomer Performance N/A
Completed NCT04769882 - Er:YAG Laser Effects on Microbial Population in Conservative Dentistry N/A
Completed NCT04971317 - The Influence of Simple, Low-Cost Chemistry Intervention Videos: A Randomized Trial of Children's Preferences for Sugar-Sweetened Beverages N/A
Active, not recruiting NCT04475679 - Clinical Evaluation of Adhese Universal DC in the Indirect Restorative Therapy N/A
Completed NCT05438381 - Comparison of Clinical and Radiographic Outcomes of SMART Technique vs ART in Primary Molars N/A
Not yet recruiting NCT03037814 - Clinical Performance of Restorative Materials in Primary Teeth N/A
Active, not recruiting NCT05202665 - Resin Infiltration and Fluoride Varnish Lesion Arresting Efficacy on Non-cavitated Proximal Lesion N/A
Terminated NCT01147835 - Herbal Lollipops on Oral Bacterial Levels and DMFT/Dmft Scores of Children With Asthma Using Inhalers N/A
Not yet recruiting NCT04033263 - Maintaining Oral Health With Bio-products N/A
Enrolling by invitation NCT04438252 - Evaluation of Reliability of CarieScan PRO Compared With Digital Radiograph and ICDAS-II in Detection of Carious Lesions N/A
Not yet recruiting NCT03609034 - Knowledge, Attitude and Practice of a Group of Egyptian Dental Interns Toward Caries Risk Assessment
Completed NCT02912000 - TEACH: Technology Evaluation to Address Child Health N/A
Completed NCT02473107 - Impact of Detecting Initial and Active Caries Lesions in Primary Teeth N/A
Active, not recruiting NCT02537184 - Impact of Two Recall Intervals on Dental Caries Incidence and Other Outcomes of Preschool Children N/A
Completed NCT01950546 - Nanosilver Fluoride to Prevent Dental Biofilms Growth Phase 1
Recruiting NCT02734420 - Effect of Photodynamic Therapy With Low-level Laser on Infected Dentin in Primary Teeth: A Controlled Clinical Trial Phase 1
Completed NCT02020681 - Effect of Curodont Repair or Placebo on the Remineralisation in Patients With Class 5 Carious Lesions N/A
Completed NCT02234609 - Effectiveness of Modified Class IV Atraumatic Restorative Treatment N/A
Completed NCT02426619 - Arresting Active Dental Caries in Preschool Children by Topical Fluorides Phase 2/Phase 3
Completed NCT01623362 - Evaluation of a Low Fluoride Dentifrice for Caries Control Phase 3