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Deglutition Disorders clinical trials

View clinical trials related to Deglutition Disorders.

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NCT ID: NCT03167892 Terminated - Clinical trials for Dysphagia, Oropharyngeal

Oral Screens in Post Stroke Training

Start date: September 15, 2017
Phase: N/A
Study type: Interventional

Stroke is a common disease in older people, and often leads to various degrees of disability. Dysphagia is one such consequence which is associated with aspiration pneumonia and malnutrition. There are studies showing that oral screen-training may reduce dysphagia, but the method is insufficiently evaluated. Since treatment with an oral screen is easy, relatively quick and cheap, it is of high relevance to perform a strict and unbiased study to assess the feasibility and efficacy of the intervention. Thus, the aim of the present study is to evaluate the effect of daily oral screen training in post-stroke patients with dysphagia. A randomized controlled clinical study will be performed in subjects who have had a first stroke 8-12 months earlier and suffer from dysphagia. The intervention consists of daily oral screen training for 3 months. In total 70 subjects will be randomized to intervention or control. The changes in swallowing capacity is the main outcome, and secondary outcomes are subjective swallowing problems, lip force, chewing function and quality of life. Improved oral motor function and decreased dysphagia in post-stroke patients will result in an improved quality of life for the individual, and also reduce hospitalization and health care costs.

NCT ID: NCT03163355 Completed - Swallowing Disorder Clinical Trials

Comparison of Pureed Rice Using a Gelling Agent and Standard Pureed Rice

Start date: May 1, 2017
Phase: N/A
Study type: Interventional

The texture of the pureed diet is likely to be most useful factor predictive of the prevention of aspiration pneumonia. However, it has not been previously reported what kinds of texture of the pureed diet can prevent aspiration pneumonia. Using endoscopic swallowing evaluation, we attempt to compare two kinds of the pureed diets to choose the better texture of pureed diets in elderly patients with severe dysphagia.

NCT ID: NCT03147755 Completed - Clinical trials for Deglutition Disorders

Prevalence, Risk Factors and Complications of Oropharyngeal Dysphagia in Stroke Patients

Marato-11
Start date: May 2010
Phase:
Study type: Observational

Oropharyngeal dysphagia (OD) is a common morbidity after stroke that disrupts swallowing physiology. The investigators aimed at evaluating the prevalence of oropharyngeal dysphagia (OD) after stroke and analysing the risk factors and associated complications.

NCT ID: NCT03145740 Completed - Clinical trials for Deglutition Disorders

Intensive Faciltiation of Swallowing in Patients With Severe Dysphagia After Acquired Brain Injury

Start date: April 2014
Phase: N/A
Study type: Interventional

This study is a randomized controlled trial (RCT). Patients after severe acquired brain injury (ABI) were randomised in addition to the individual daily rehabilitation program to intensive Facial Oral Tract Therapy (F.O.T.T.®) (intervention group) or unspecific treatment: washing face, brushing teeth, without facilitating swallowing (control group). The duration of the intervention period was 15 working days (3 weeks). The intervention in both groups was twice a day.

NCT ID: NCT03133650 Active, not recruiting - Clinical trials for Esophagogastric Cancer

A Trial of a New Type of Photodynamic Therapy (VTP) in the Treatment of Patients With Cancer of the Esophagus Who Have Trouble Swallowing

Start date: April 26, 2017
Phase: Phase 1
Study type: Interventional

The purpose of this study is to establish the highest dose of laser light for WST-11 VTP to treat obstruction from esophageal cancer that can be safely given.

NCT ID: NCT03131869 Recruiting - Clinical trials for Deglutition Disorders

Development of Novel, Biophysically Designed Fluids for Swallowing Disorders

Start date: February 22, 2017
Phase: N/A
Study type: Observational

People suffering from swallowing disorders (dysphagia) have a hard time swallowing liquids that are too thin (like water or coffee) or too thick, correctly. They can have health problems, such as chest infections and malnutrition because when they try to drink, some of the liquid "goes down the wrong pipe" and into the lungs. To help people with dysphagia, Swallow Solutions is developing thickened liquids that have added nutrition, taste good, and quench thirst, but are still easy and safe to swallow.

NCT ID: NCT03082170 Not yet recruiting - Dysphagia Clinical Trials

The Effect of Obstructive Sleep Apnea Operations on the Swallowing Function

Start date: June 1, 2017
Phase: N/A
Study type: Interventional

The investigators hypothesize that partial robotic tongue base resection surgery and / or soft palate surgery, as a treatment for sleep apnea affect the swallowing quality.In order to characterize the dysphagia The investigators will locate participants undergoing this surgery more than six months ago.The investigators will test their swallowing by fiberoptic endoscopic evaluation of swallowing (FEES) and let participants fill out a questionnaire regarding swallowing disorders swallowing dysfunction questionnaire (SDQ). Also the investigators will use data collected from participants who have undergone this surgery and already had these tests due to swallowing complaints.

NCT ID: NCT03066167 Completed - Esophageal Cancer Clinical Trials

Validation of Instruments Used for Assessment of Dysphagia in Patients With Esophageal Cancer

Start date: November 2010
Phase:
Study type: Observational

This study validates 3 well known dysphagia scores for dysphagia due to malignancies of the oesophagus and gastro-oesophageal junction and to the Swedish language.

NCT ID: NCT03050957 Completed - Clinical trials for Deglutition Disorders

Effect of Oral Menthol on the Swallow Response of Patients With Oropharyngeal Dysphagia Associated With Neurological Diseases and Aging

Start date: May 2013
Phase: Phase 2
Study type: Interventional

Oropharyngeal dysphagia (OD) is the most frequent digestive disorder in older people (>70 years) and has been recently recognized as a geriatric syndrome. The main features of OD are: a high prevalence and severe complications either related with the decreased swallowing efficacy with 45% prevalence of malnutrition or due to decreased swallowing safety with 50% prevalence of aspiration pneumonia that increases hospital stay by 100% and leads to a 50% of mortality rate. However, there is no specific pharmacologic treatment for OD in older patients yet. Treatments are now evolving from compensation to active treatments aiming to restore the swallowing dysfunction and some groups have been looking for new therapeutic strategies. The main goal of this study is to evaluate the effect of administering menthol in bolus on the swallowing response in elderly and neurogenic patients with OD. In addition, this study will also assess the side effects of this pharmacological strategy.

NCT ID: NCT03048916 Completed - Stroke Clinical Trials

Dysphagia After Different Swallowing Therapies

Start date: August 1, 2010
Phase: N/A
Study type: Interventional

Dysphagia after stroke is associated to increased pulmonary complications and mortality. The swallowing therapies could decrease the pulmonary complications and improve the quality of life after stroke. The swallowing therapies include dietary modifications, thermal stimulation, compensatory positions, and oropharyngeal muscle stimulation. Most researchers used clinical assessments and videofluoroscopy to evaluate the effect of the swallowing therapies. Some authors performed functional magnetic resonance imaging (fMRI) to investigate the brain neuroactivity during swallowing with tasks in normal adults and unilateral hemispheric stroke patients. The aim of this study is to explore the effect of swallowing therapies not only in clinical swallowing function but also brain plasticity of acute stroke patients with dysphagia by videofluoroscopy and fMRI.