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Deafness clinical trials

View clinical trials related to Deafness.

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NCT ID: NCT03321006 Completed - Depression Clinical Trials

Treating Hearing Loss to Improve Mood and Cognition in Older Adults

Start date: May 30, 2018
Phase: Phase 4
Study type: Interventional

Age-related hearing loss (ARHL) is the third most common health condition affecting older adults after heart disease and arthritis and is the fifth leading cause of years lived with disability worldwide. Many hearing-impaired older adults avoid or withdraw from social contexts in which background noise will make it difficult to communicate, resulting in social isolation and reduced communication with family and friends.Social isolation and loneliness have been linked to numerous adverse physical and mental health outcomes, including dementia, depression, and mortality, and they may also lead to declining physical activity and the development of the syndrome of frailty. In this project it is hypothesized that untreated ARHL represents a distinct route to developing Late-life Depression (LLD) and that individuals with comorbid ARHL/LLD are unlikely to respond to treatments (i.e., antidepressant medication) that do not treat the underlying hearing problem. Initial studies suggest remediation of hearing loss using hearing aids or cochlear implantation may decrease depressive symptoms acutely and over the course of 6 to 12 months follow-up. However, the clinical significance of these findings is obscured by lack of rigorous control groups, failure to objectively document hearing aid compliance, and enrollment of study populations lacking syndromal depression or even a threshold symptom score.

NCT ID: NCT03319524 Completed - Clinical trials for Retinitis Pigmentosa

Clinical and Genetic Testing of Patients With Usher Syndrome

Start date: May 17, 2017
Phase:
Study type: Observational [Patient Registry]

This study is aimed to characterize Russian population of Usher patients.

NCT ID: NCT03309553 Completed - Hearing Loss Clinical Trials

Reducing Childhood Hearing Loss in an Alaska Native Population Through a New School Screening and Referral Process That Utilizes Mobile Health and Telemedicine

Start date: October 10, 2017
Phase: N/A
Study type: Interventional

Hearing loss is a common health problem in Alaska. Up to 75% of children growing up in Alaskan villages experience frequent ear infections, one of the major treatable causes of hearing loss. Children with even mild hearing loss face many challenges. These children often experience speech and language delays and have trouble in school. Teens with hearing loss are more likely to drop out of school, and are at risk for having difficulty finding jobs as adults. Promptly diagnosing and treating hearing loss is important for preventing these consequences. Alaska mandates school-based hearing screening, but many children with hearing loss are not identified by the current screening protocol, and most who are referred never make it into the healthcare system for diagnosis and treatment. Alaska has already developed innovative strategies to address hearing loss. A network of village health clinics staffed by community health aides provide local care, and telemedicine has been adopted in over 250 village clinics statewide. Despite being widely available, telemedicine has not yet been used in school hearing screenings to speed up the referral process. Norton Sound Health Corporation has partnered with Duke and Johns Hopkins Universities to explore whether a new school screening and referral process that incorporates mobile, or mHealth, screening and telemedicine referral will reduce childhood hearing loss disparities in the Norton Sound region. Children from kindergarten through 12th grade in 15 Norton Sound villages will receive the current school screening protocol and the new mHealth screen. Villages will then be randomized to continue the current primary care referral process or to adopt telemedicine referral for school screenings. The investigators hypothesize that the new mHealth screening protocol will identify more children with hearing loss, and telemedicine referral will reduce time to diagnosis. By better identifying hearing loss and speeding up diagnosis and treatment, the investigators expect the burden of childhood hearing loss to drop, hearing-related quality of life to improve, and school performance to improve in villages with telemedicine referral compared to current primary care referral villages. If the study shows these positive effects, mHealth screening and the telemedicine referral process could be implemented in school districts across the state of Alaska to reducing childhood hearing loss disparities statewide.

NCT ID: NCT03289845 Completed - Deafness Unilateral Clinical Trials

Clinical Survey of Oticon Medical Ponto BHX Implant

Start date: November 5, 2015
Phase: N/A
Study type: Interventional

Investigation of stability of the BHX implant in adult patients indicated and counselled for a bone anchored hearing aid system. Patients are followed according to clinical practice for a total of 12 months in the study. Stability of the implant is evaluated by implant stability quotient.

NCT ID: NCT03288753 Completed - Clinical trials for Sensorineural Hearing Loss

Comparison Between Neuro 1 and Neuro 2 Cochlear Implant Speech Processors

Start date: October 2, 2017
Phase: N/A
Study type: Interventional

The present study aims to evaluate patient satisfaction and audiological performance with their current cochlear implant speech processor, the Neuro 1, and to compare it with the satisfaction and performance obtained with the new speech processor, the Neuro 2.

NCT ID: NCT03281967 Completed - Mixed Hearing Loss Clinical Trials

Clinical Survey of Minimally Invasive Ponto Surgical Technique (MIPS)

Start date: June 9, 2017
Phase: N/A
Study type: Interventional

The objective of the study is to compare the outcomes after a surgical procedure with minimally invasive Ponto surgery (MIPS, test group) and tissue preservation surgery (control) for placing Oticon Medical Ponto implants and abutments.

NCT ID: NCT03279367 Completed - Hearing Loss Clinical Trials

Optimisation of Hearing Aid Fitting

Start date: December 22, 2017
Phase:
Study type: Observational

This study aims to explore if objective brain responses to speech stimuli (words and running speech) can be used to evaluate hearing aid fitting in adults. Objective brain responses would be beneficial, as they could be used to evaluate hearing with people who are incapable or unwilling to provide subjective responses. The study aims to determine if EEG responses to speech sounds are sensitive to the effects of hearing aids for hearing aid users. Secondary, the study will look into the need for using speech stimuli in order to obtain more robust responses compared to current clinical standards.

NCT ID: NCT03260062 Completed - Deafness, Bilateral Clinical Trials

Parent-Child Early Approaches to Raising Language Skills (PEARLS) Intervention

PEARLS
Start date: April 11, 2016
Phase: N/A
Study type: Interventional

The purpose of this research study is to develop and evaluate a parent training program, which aims to improve language. The study is being conducted to see if teaching parents positive parenting techniques and behavior strategies will improve the rate of language development in children with cochlear implants when compared to standard speech therapy (e.g., auditory-verbal therapy).

NCT ID: NCT03255473 Completed - Clinical trials for Sudden Sensorineural Hearing Loss (SSNHL)

High Dose Oral Steroids in Sudden Sensorineural Hearing Loss

Start date: August 30, 2017
Phase: Phase 2
Study type: Interventional

Compare hearing outcomes between treatment with dexamethasone versus prednisone in participants who have been diagnosed with unilateral SSNHL (sudden sensorineural hearing loss).

NCT ID: NCT03212924 Completed - Clinical trials for Sensorineural Hearing Loss

Listening Effort in Cochlear Implant Users

Start date: September 19, 2017
Phase: N/A
Study type: Interventional

Listening with a cochlear implant remains difficult and most listeners will report high levels of listening effort.The present study is a "pilot" aiming to evaluate listening effort for cochlear implant users. The listening effort is measured with pupillometry, by monitoring the variations of pupil size in response to different stimuli. The size of the pupil is known to increase with the listening effort. The listening effort is evaluated in two different situation: speech perception in quiet and speech perception in noise. The pupillometry measures will be compared for the two listening conditions. Moreover, the study will evaluate the relationship between objective (pupil dilatation) and subjective measures (auto evaluation) of listening effort, and between speech comprehension, cognitive abilities and listening effort.