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Cysts clinical trials

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NCT ID: NCT00426153 Completed - Liver Diseases Clinical Trials

Octreotide in Severe Polycystic Liver Disease

Start date: January 2007
Phase: Phase 2/Phase 3
Study type: Interventional

This study will evaluate the effect of Octreotide LAR® on the liver volumes of patients with severe polycystic liver disease who are not candidates or decline surgical treatments such as liver cyst fenestration, liver resection or liver transplantation. A total of 42 patients will be recruited -14 who will receive placebo and 28 the study drug. Preliminary evidence indicates that this drug is safe and non-toxic in other disease states. Treatment with this drug holds promise not only for individuals with liver involvement, but also for many more patients with polycystic kidney disease.

NCT ID: NCT00280514 Completed - Abscess Clinical Trials

Plasma and Abscess Fluid Pharmacokinetics of Cefpirome and Moxifloxacin After Single and Multiple Dose Administration

Start date: January 2006
Phase: Phase 4
Study type: Interventional

Penetration of cefpirome and moxifloaxacin into abscess fluid of humans will be tested. Patients with an abscess scheduled for drainage will receive study drugs (single or multiple dose), pus samples and plasma samples will be collected and analyzed by High pressure liquid chromatography (HPLC). Pharmacokinetics of the study drugs in pus and plasma will be determined using a pharmacokinetic model.

NCT ID: NCT00222898 Completed - Pancreatic Neoplasm Clinical Trials

Cancer Detection in Pancreatic Cysts

Start date: June 2004
Phase: N/A
Study type: Observational

The purpose of this study is to assist with early and accurate diagnosis of cancer in pancreatic cysts based on the analysis of DNA obtained by endoscopic ultrasound guided fine needle aspiration

NCT ID: NCT00222066 Completed - Ovarian Cyst Clinical Trials

Effect of Fetal Ovarian Cyst Aspiration to Prevent Torsion

Start date: June 2001
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether prenatal ovarian cyst aspiration is effective and safe to prevent perinatal ovarian torsion.

NCT ID: NCT00165958 Completed - Epidermal Cyst Clinical Trials

Comparison of Excision Versus Punch Incision in the Treatment of Epidermal Cysts

Start date: January 2005
Phase: Phase 4
Study type: Interventional

The purpose of this trial is to compare two standard of care treatments for removing epidermal cysts. Surgical excision removes the entire cyst but requires a larger hole in the skin. A punch incision makes a smaller hole through which the cyst can be removed. The trial's purpose is to determine if one method is better than another in terms of recurrence, infection, or other side effects.

NCT ID: NCT00001912 Completed - Seizures Clinical Trials

Brain Tissue Swelling and Seizure Activity in Inactive Cysticercosis

Start date: August 10, 1999
Phase: N/A
Study type: Observational

This study will examine what causes seizures in patients with cysticercosis (pork tapeworm infection). A better understanding of this could lead to improved methods of controlling or preventing seizures. In humans, the pork tapeworm (Taenia solium) lives in the small intestine. The parasite's microscopic eggs travel around the body-including to the brain-where they develop into cysts. Usually, the cysts don't cause symptoms until they die. Then, they provoke an inflammatory reaction that irritates the brain, causing seizures and other symptoms. The inflammation eventually goes away, but the dead cysts remain. Calcium deposits often form where the cysts are. Some of the calcified cysts develop swelling around them that seem to be associated with the development of seizures. This study will explore how and why these dead, calcified cysts continue to cause seizures. In so doing, it will try to determine: 1) the best diagnostic imaging method for detecting swelling around the cysts; 2) how often swelling occurs; and 3) what makes some cysts prone to swelling and related seizure activity, while others are not. Patients with cysticercosis who have had seizures or who have known or possible swelling around calcified cysts will be studied with various tests, including magnetic resonance imaging (MRI), computed tomography (CT) scans, electroencephalography (EEG), blood tests, and possibly lumbar puncture. Patients will be studied for two cycles of seizures (during active and quiet periods) or a maximum 4 years.