CTLA4 Haploinsufficiency Clinical Trial
Neurologic and Immunologic Characteristics of CTLA-4 and LRBA Hereditary Deficiency
CTLA4 and LRBA deficiencies are rare genetic disorders, recently described, and associated with multiple clinical features. It ranges from recurrent infections, auto-immunity, and organ infiltration with lymphocytes. Neurologic syndroms are described in up to 30% of patients, yet they are poorly defined to date. Early recognition of a specific pattern can be important, given that there is a targeted therapy in this situation.
|Source||University Hospital, Montpellier|
|Status||Active, not recruiting|
|Start date||February 1, 2021|
|Completion date||September 30, 2021|