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An Assessment of the Feasibility and Safety of Conservative Oxygen Therapy in Critically Ill Patients

Critical Illness Clinical Trial

Official title:
A Before-and-after Assessment of Conservative Oxygen Therapy vs. Standard Care in Critically Ill Mechanically Ventilated Patients

Clinical Trial Summary

The investigators hypothesize that it is feasible and safe to deliver a conservative approach to oxygen therapy in mechanically ventilated critically ill patients (a tiem frame of, on average,10 days).

Clinical Trial Description

1. Identify patients likely to require ventilation until the day after tomorrow (a time frame of 36 hours of average)

2. Deliver a conservative oxygen therapy protocol while in ICU (a time frame on average of 10 days)

3. Target an oxygen saturation between 90 and 92%

4. Adjust FiO2 to achieve target SaO2 at all times

5. Assess percentage of time patient is within target

6. Assess for safety of this approach ;

Study Design

Allocation: Non-Randomized, Endpoint Classification: Safety Study, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01684124
Study type Interventional
Source Austin Health
Contact
Status Completed
Phase Phase 1/Phase 2
Start date March 2012
Completion date March 2013
View Details
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