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NCT ID: NCT05695157 Recruiting - Wound Infection Clinical Trials

Clinical Performance and Safety of Suture-TOOL

Start date: January 10, 2023
Phase: N/A
Study type: Interventional

The goal of this single arm intervention study is to investigate the safety and performance of a suturing device for closure of the midline incision after open abdominal surgery. The study population consists of 38 patients selected for open abdominal procedures for malignant and benign colorectal disease. The main question it aims to answer is: • If the device facilitates a Suture-Length to Wound-Length (SL/WL) ratio of 4:1 Participants laparotomy wound will be closed with the device at the end of the operation and closure related data as closure time and SL/WL ratio will be calculated. The wound will be assessed for infection during the postoperative stay and the chart will be reviewed for wound dehiscence and wound infection.

NCT ID: NCT05693441 Recruiting - Clinical trials for Age-related Cognitive Decline

Study on the Chronic and Acute Effects of Nordic Berry Beverage on Cognitive Function

SCANBerry
Start date: January 17, 2023
Phase: N/A
Study type: Interventional

The aim of the current study is to investigate whether acute and 12-weeks daily intake of Nordic berries can improve cognitive abilities of adults without cognitive disease, and whether the effect can be linked to changes in metabolic parameters.

NCT ID: NCT05693324 Recruiting - Quality of Life Clinical Trials

Minority Joy and Minority Stress in Trans People: an Intervention Study

Start date: December 1, 2022
Phase: N/A
Study type: Interventional

The aim of this project is to get a better understanding of transgender and gender non-conforming (TGNC) people's experiences of minority joy and minority stress over time. Further, the project explores how these experiences covary with psychiatric and physical ill health and quality of life before, during and after a TGNC affirmative intervention in adult and adolescent participants over 15 years of age. The intervention consists of three parts, given in randomized order: 1. Psychoeducation and behavioral interventions about external minority stress, 2. Cognitive interventions targeting worry, and 3. Self-compassion aiming to relieve internalized transphobia. This project uses a mixed methods data collection consisting of interviews as well as a replicated single case design (SCED). More detailed pre- and post measurements will also be collected. The interviews enable us to explore minority joy in detail, as well as getting feedback about the feasibility and acceptability of the intervention. The SCED enables us to visualize the interplay between everyday experiences and health, while testing the affirmative program. The project will provide much needed knowledge, which in turn will improve health in TGNC people.

NCT ID: NCT05693285 Completed - Clinical trials for Cardiovascular Diseases

Preterm Birth and Biomarkers for Cardiovascular Disease

BIO-PRETERM
Start date: November 14, 2022
Phase:
Study type: Observational

Preterm birth is associated with maternal increased risk of cardiovascular disease later in life. In an observational case- control study, we want to evaluate whether women with preterm birth have increased levels of biomarkers for cardiovascular disease, to reveal potential pathophysiological mechanisms in common.

NCT ID: NCT05693155 Not yet recruiting - Gambling Disorder Clinical Trials

Experience of the Nationwide Gambling Self-exclusion Service Spelpaus - Effects and Limitations of a Unique Harm Reduction Instrument for Problem Gambling

Start date: January 30, 2023
Phase:
Study type: Observational

Qualitative interview study addressing the effects and limitations of a unique, government-based, nationwide self-exclusion service for the reduction of gambling-related harm. This service, which allows for individuals at risk of gambling problems (and for anyone) to self-exclude from all licensed gambling in the country, is unique in its nationwide, non-gambling-operator-dependent and multi-operator design. It is a promising tool for the prevention and harm reduction in relation to problem gambling and gambling disorder, but emerging research data report considerable limitations including high access to non-licensed gambling allowing users to breach the voluntary self-exclusion and relapse into hazardous gambling practices. This study will examine effects and limitations of the system, for gamblers and for concerned significant others of gamblers, through qualitative interviews addressing their experience of the system.

NCT ID: NCT05692778 Recruiting - Clinical trials for Diabetes Mellitus, Type 2

Optimized Care of People With Diabetes and Foot Complication in Primary Care

Start date: January 1, 2020
Phase:
Study type: Observational

The goal of this observational study is to create and evaluate and new management, by using eHealth tools, to prevent diabetic foot ulcers. The main questions it aims to answer are: 1. Validation a. Is a method for foot assessment, that uses eHealth tools, valid regarding its usefulness? b. Is a method for foot assessment, that uses eHealth tools, reliable regarding the generated risk stratification? 2. Mapping 1. How do health care professionals and patients with diabetes experience that the future foot examination should be designed? 2. What experiences have health care professionals and patients with diabetes to use an eHealth tool supporting the annual foot examination? 3. Interviews - to use a paper format supporting a structured foot assessment a. How do health care professionals experience to use a structured foot form, in paper form? 4. Interviews - footwear a. What factors that influence how patients with diabetes choose their footwear? 5. Interviews - usability test of using an eHealth tool a. How could a digital eHealth tool be designed? b. How could a digital eHealth solution be implemented, managed and spread in public health care setting? i. Participants will: 1. fill in questionnaires 2. be interviewed 3. test eHealth solutions supporting the foot examination 6. Experiences of using an eHealth tool supporting the foot assessment a. How could a digital eHealth tool be designed? 7. Questionnaires regarding self-perceived quality of life, the experiences of the visit at the care unit, transportation to the care unit. a. Patients that visits care fills in a questionnaire regarding self-perceived quality of life (EQ-5D), a modified version of National Patient Survey, the diabetes questionnaire and a questionnaire regarding their travels and time for travels to and from the visit to the care unit. 8. Critical evaluation of complexity 1. Exists complexity in the development, test, management, spread and sustain of an eHealth tool supporting foot examination and self-care of the feet in diabetes. 2. How could a digital eHealth solution be implemented, managed and spread in public health care setting? 9. Long term effect a. What is the long-term effect of using an eHealth tools supporting a structured foot examination?

NCT ID: NCT05691803 Recruiting - Physical Inactivity Clinical Trials

Understanding Motivation Towards Exercise to Enhance Physical Activity on Prescription Adherence - Feasibility Study

UMEPA-F
Start date: January 30, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to explore feasibility and evaluate methods to investigate changes in physical activity, function and psychometrics in relation to an exercise intervention in physically inactive middle-aged men and women. The main questions it aims to answer are: - Is the exercise intervention feasible regarding retention and user experience? - Is the evaluation methods on physical activity, function and psychometrics suitable for the present study? - Is there an intervention effect in physical activity, function and psychometrics at three and six month post baseline? - Can barriers and facilitators towards increased physical activity be identified in the two groups of the study? All participants will first receive standard care for physically inactive patients, i.e. Physical activity on Prescription (PaP), followed by allocation to a control or an exercise intervention (EI) group. The control group are asked to adhere to their PaP and the EI group will be offered an additional exercise intervention for 12 weeks consisting of 1-2 training sessions per week of a combination of aerobic and resistance training at a private fitness center. Feasibility of the exercise intervention will be evaluated based on retention rates and user experience. Additionally, researchers will compare physical activity, function and psychometrics in the control and EI groups at three and six months to evaluate the suitability of the chosen methods and to get preliminary data on the intervention effect. Finally, interviews with the participants in the control and EI groups will be performed at the end of the study in order to explore barriers and facilitators towards increased physical activity in formally inactive patients.

NCT ID: NCT05689931 Recruiting - Asthma Clinical Trials

Blood Leukocyte Profiling in Eosinophilic Type 2 Asthma: Influence of Systemic IL-5 Targeting

Start date: February 1, 2023
Phase:
Study type: Observational

The goal of this exploratory and observational prospective study is to study the composition and phenotypes of blood leukocytes collected from asthmatic patients before and after instantiated treatment with the interleukin-5 neutralizing antibody mepolizumab. Comparisons will be made to leukocyte profiles in patients already on mepolizumab treatment, asthma patients without any biological treatment, and non-diseased control subjects.

NCT ID: NCT05689762 Recruiting - Healthy Lifestyle Clinical Trials

Promotion of Healthy Lifestyle Habits in a Primary Care Setting

Start date: January 10, 2023
Phase: N/A
Study type: Interventional

Intervention aiming to promote healthy dietary and physical activity behaviors in adults with low socio-economic position in a primary health care setting

NCT ID: NCT05689684 Recruiting - Diabetes Type 2 Clinical Trials

Arabinoxylan-oligosaccharides (AXOS) for the Management of Type-2 Diabetes

Start date: November 7, 2022
Phase: N/A
Study type: Interventional

The project aims to achieve significantly improved clinical care for type 2 diabetes. The current standard treatment metformin has low adherence due to its main side effect gut dysbiosis, which also results in more complications and high overall costs. Prebiotics have been suggested as a medical food and might be helpful as adjuvant management in type 2 diabetes and other metabolic diseases. Carbiotix AB has developed, a corn fiber extract containing arabinoxylan-oligosaccharides (AXOS), which have great potential for improving gut health. In this project, it will be investigated whether the intake of a hybrid product containing AXOS together with metformin can significantly improve glucose metabolism and gut health in patients with type 2 diabetes.