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NCT ID: NCT05707312 Recruiting - Endometrial Cancer Clinical Trials

Staging Endometrial caNcer Based on molEcular ClAssification

Start date: January 1, 2023
Phase:
Study type: Observational

The SENECA study tries to evaluate the rate of lymph node involvement depending on the molecular subgroup in early-stage endometrial cancer (I/II) patients undergoing surgery as part of their treatment.

NCT ID: NCT05706792 Completed - Dementia Clinical Trials

Effectiveness of the Nordic Sensi Chair in the Treatment of Dementia Behavioral Disorders (NSC-DEMEN)

NSC-DEMEN
Start date: May 20, 2022
Phase: N/A
Study type: Interventional

The main objective of this study is to evaluate the effectiveness of the Nordic Sensi® Chair (NSC) in the management of behavioral symptoms of dementia (BPSD) in real clinical practice in people with dementia admitted to nursing homes. The secondary objective of the present study is to assess its benefits on the performance of the daily work activities of care staff. Although over time the BPSD have been treated predominantly with pharmacological measures, there is now sufficient scientific evidence to support the use of non-pharmacological therapies (NPT) for their management.Within this context, only a few studies have evaluated the use of rocking chairs for people with dementia. Modern rocking chairs may be suitable for long-term care because rocking, a rhythmically repeated movement, can contribute to psychosocial wellbeing . In this regard, it is a focus of attention to consider the therapeutic role of the Nordic Sensi® Chair in the treatment of BPSD based on its ability to offer patients a sensory experience that brings the benefits of music therapy, therapeutic tactile stimulation, vestibular stimulation, and relaxation in an integrated way, especially those in nursing homes. The NSC is an electrically operated rocking chair with built-in MusiCure music. It is equipped with an integrated audio system with music recording. The NSC has three different programs: Relax for deep relaxation, Refresh for recovery and Comfort for gentle relaxation. In addition to musical programming, the NSC provides predefined tactile stimulation and rocking motion, for a relaxing multi-sensory experience. In this study, the 20 minutes NSC deep relaxation program (Relax Program) will be used. Participants are randomly assigned to two groups of equal size: a treatment group that receives three times a week one session per day of 20 minutes in the Relax for deep relaxation program of the NSC and a control group that does not participate in the activity mentioned for the treatment group, but receives, at the same time and duration, the care and activities that are part of the daily routines. Although cognitive and functional symptoms have been the hallmarks of dementia, in recent years behavioral and psychological symptoms of dementia (BPSD) have become increasingly important. In all cases, BPSD is always one of the most important challenges that both the patient and their caregivers will face throughout the course of the disease.

NCT ID: NCT05706519 Recruiting - Clinical trials for Coronary Heart Disease

Metabolomics, Genomics and Nutrition for Cardiovascular Disease Precesion Medicine

OMIC-CARD
Start date: December 19, 2022
Phase:
Study type: Observational [Patient Registry]

The objective of this project is to validate, through high-throughput advanced metabolomics techniques, the nutritional assessment tools to be used in the IMPaCT cohort. At the same time, the ability of metabolomics fingerprints of nutritional patterns to discriminate between patients with and without major cardiovascular disease will be identified. Finally, the modification of these predictions will be evaluated based on the genetic profiles. The main hypothesis holds that the integration of metabolomics, genomic and nutritional information will serve to personalize the approach to cardiovascular disease, both in prevention and treatment, and that these tools, in turn, will be valid enough to be applied systematically and efficiently in the IMPaCT cohort.

NCT ID: NCT05706220 Enrolling by invitation - Multiple Sclerosis Clinical Trials

Visual Processing Speed and Objective Analysis of Ocular Movements in Multiple Sclerosis

Start date: June 13, 2022
Phase:
Study type: Observational

This project aims to analyze ocular motility problems, visual processing speed and microperimetry, and their relationship with consolidated retinal structural biomarkers (optical coherence tomography, OCT) in patients with Multiple Sclerosis w/w reading complaints comparing with healthy subjects.

NCT ID: NCT05705765 Recruiting - Balance Training Clinical Trials

Effects on Balance of Suspension Exercise vs. Exercise on Unstable Surfaces.

Start date: January 9, 2023
Phase: N/A
Study type: Interventional

Most human movements are executed while in a state of postural instability. For this reason, instability training is a highly-specific method that is intended to improve balance and postural control. This research aimed to determine the effect of instability training on the balance of individuals with similar baseline abilities, who initiated training within different stability conditions. Research question: Does different type of instability training determine improvements in balance?

NCT ID: NCT05705752 Recruiting - Balance Training Clinical Trials

Balance Training Vs Pilates Training

Start date: January 9, 2023
Phase: N/A
Study type: Interventional

Many pathologies present balance disturbances, however, other types of therapies such as Pilates are increasingly used within the Physiotherapy profession. It is therefore necessary to know the effects that this type of exercise has compared to the traditional method of balance training in order to make good use of this type of therapy. The objective of the study will be to know if there are differences between both types of training on the balance of the participants.

NCT ID: NCT05704777 Not yet recruiting - Glaucoma Clinical Trials

Exercise Intervention in Primary Open-angle Glaucoma

EYE-FIT
Start date: February 1, 2023
Phase: N/A
Study type: Interventional

EYE-FIT is a randomized clinical trial with a two-arm parallel design aimed at assessing the impact of performing a structured and supervised physical training program on the different variables associated with glaucoma progression in pharmacologically treated primary open angle glaucoma patients. This intervention will include a supervised 24-weeks concurrent (endurance + resistance) training program comparing its influence to the standard care.

NCT ID: NCT05704335 Active, not recruiting - Migraine Clinical Trials

InfluenCEF Study: Study on the Headache Associated With Influenza Infection

INFLUENCEF
Start date: December 20, 2022
Phase:
Study type: Observational

The goal of this observational analytic study with a cohort desing is to evaluate the epidemiology, risk factors and clinical phenotype of headache during Influenza infection. The study will be done in collaboration with the Healthcare Sentinel Network of Castile and Leon (Red Centinela Sanitaria de Castilla y León, RCSCYL) and the National Influenza Center of Valladolid (CNGV). First, the historical data of the VIGIRA network of the 2010-2022 flu seasons will be analyzed, assessing the epidemiology and risk factors of headache during Influenza infection; and second, a study with a case series design with prospective follow-up will be carried out for the incident cases of the 2022-2023 and 2023-2024 Influenza seasons, evaluating the clinical phenotype and the duration of the headache.

NCT ID: NCT05704153 Recruiting - Clinical trials for Systemic Lupus Erythematosus

Modelling and Control of Non-invasive Vagus Nerve Stimulation for Autoimmune Diseases (1A)

VaNeSA
Start date: September 30, 2022
Phase: N/A
Study type: Interventional

The overall goal of this clinical trial is to evaluate the causality relationship between the non vagus nerve stimulation waveform parameters and the therapeutic effect. Thus, unlocking a pathway to optimize parameters that maximize the benefits of therapy and minimize unwanted side effects. The experimental design includes the analysis of physiological signals, clinical biomarkers of disease, and clinical outcomes to determine the most effective measures for the monitoring, optimization, and personalization of non vagus nerve stimulation in systemic lupus erythematosus disease.

NCT ID: NCT05703100 Recruiting - Energy Metabolism Clinical Trials

Lactate Profile and Fat Oxidation During Exercise

LacFat
Start date: January 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test whether changes in lactate kinetics during exercise (due to glycogen depletion or hyperthermia) alter the pattern of fat oxidation during a maximal incremental cycle ergometer test in healthy young active people. The main questions it aims to answer are: - Will a rightward shift in lactate kinetics, induced by a previous glycogen depletion, produce a rightward shift in fat oxidation? - Will a leftward shift in lactate kinetics due to an increase in ambient temperature produce a leftward shift in fat oxidation? Participants will perform three maximal incremental tests in three different conditions: - one in the control condition; - one with glycogen depletion; - and one with ambient heat (the latter two in randomized, counterbalanced order).