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NCT ID: NCT06439433 Completed - Clinical trials for Papillomavirus Infections

ALA-PDT in Patients With CIN2 in p16-positivity and High-risk HPV Infection

Start date: May 31, 2021
Phase: Phase 2
Study type: Interventional

Efficacy and Safety of ALA-PDT in patients with cervical intraepithelial neoplasia grade 2 (CIN2) in p16-positivity and high-risk HPV infection.

NCT ID: NCT06437912 Completed - Scar Clinical Trials

Effectiveness of Botulinum Toxin A in Preventing Scar Formation and Initial Exploration of "Optimal Concentration"

Start date: March 23, 2023
Phase: Early Phase 1
Study type: Interventional

Each year, millions of burn, trauma, or surgical patients worldwide suffer from scarring that severely affects their quality of life and social functioning. In order to prevent and treat diseases related to abnormal scar hyperplasia, clinicians and researchers have adopted various methods, such as scar grinding, surgical resection, drug injection in scar tissue, cryotherapy, laser and so on. However, these methods can not effectively inhibit the abnormal proliferation of scars and improve the adverse effects of existing scars on patients. To date, there is no accepted gold standard for the effective treatment and improvement of abnormal scar tissue.

NCT ID: NCT06437457 Completed - Clinical trials for HCC - Hepatocellular Carcinoma

Comparison of Gd-EOB-DTPA-enhanced MRI and Contrast-enhanced Ultrasound for Measuring Tumor Size of Solitary Hepatocellular Carcinoma ≤ 5cm:A Retrospective Study

Start date: January 1, 2019
Phase:
Study type: Observational

Knowing the tumor size before operation is of great significance to the choice of treatment methods of surgeons and the prognosis of patients. In this study, two commonly used imaging methods( CE-MRI/CEUS) were selected to measure and compare the tumor size before operation, in order to determine which measurement method is more accurate.

NCT ID: NCT06436963 Completed - Narrative Medicine Clinical Trials

Exploring the Application of Narrative Medicine Combined With Case-Based Learning in the Standardized Training of General Practice Residents

Start date: July 1, 2022
Phase: N/A
Study type: Interventional

This was a prospective, longitudinal, single-center nonrandomized controlled study. A total of 36 first- and second-year general practice residents of Zhejiang University School of Medicine were voluntarily enrolled in the experimental group. The remaining 9 residents served as a control group. The experimental group received narrative medicine training combined with CBL training. The control group received normal CBL training. None of the participants had previously had any training in narrative medicine. Teaching evaluation scores were measured for all subjects at baseline and 1 year after the training.

NCT ID: NCT06435182 Completed - Dry Eye Clinical Trials

Study of OT202 in Treating Moderate to Severe Dry Eye

Start date: April 10, 2023
Phase: Phase 2
Study type: Interventional

This is a phase II study to explore the optimal dosage of OT202 in treating dry eye.

NCT ID: NCT06435013 Completed - Clinical trials for Hepatocellular Carcinoma

Lenvatinib vs Bevacizumab Plus ICIs and HAIC in Unresectable HCC

Start date: December 1, 2023
Phase:
Study type: Observational

Previous studies had suggested hepatic arterial infusion chemotherapy (HAIC) combined with immune checkpoint inhibitors (ICIs) and anti-angiogenic drugs had promising anti-tumor activity in unresectable hepatocellular carcinoma (HCC). Two kinds of anti-angiogenic drugs (tyrosine kinase inhibitors [lenvatinib] and anti-VEGF antibody [bevacizumab]) were applied in first-line treatment of unresectable HCC. However, little is known about the difference of efficacy and safety between lenvatinib (LenHAP) or bevacizumab (BevHAP) combined with ICIs and HAIC in unresectable HCC.

NCT ID: NCT06434584 Completed - Diabetes Clinical Trials

Explainable Insulin Decision-making System to Assist Physicians in Diabetes Management

Start date: December 10, 2022
Phase:
Study type: Observational

The investigators plan to conduct a multi-case, multi-reader observational study with the primary objective of exploring the effects of an interpretable insulin-assisted decision-making system on physicians' (1) decision accuracy and (2) decision confidence.

NCT ID: NCT06433336 Completed - Blood Pressure Clinical Trials

Effect of Blood Pressure on Cardiovascular Outcomes and Recurrence After Catheter Ablation in Patients With Atrial Fibrillation

AF BP
Start date: January 1, 2019
Phase:
Study type: Observational [Patient Registry]

Effect of blood pressure on cardiovascular outcomes and recurrence after catheter ablation in patients with atrial fibrillation

NCT ID: NCT06433089 Completed - Nerve Block Clinical Trials

Postoperative Pain for Patients After TA-BSM

Start date: April 1, 2023
Phase:
Study type: Observational

To retrospectively analyze the intraoperative and postoperative status of patients with hypertrophic cardiomyopathy undergoing TA-BSM, and to estimate whether paravertebral nerve block can improve postoperative pain for these patients.

NCT ID: NCT06432257 Completed - Thyroid Cancer Clinical Trials

The Effect of the Application of Head Mounted Magnifying Glasses on Postoperative PTH Changes in Thyroid Surgery

Start date: January 1, 2020
Phase:
Study type: Observational

This study collected data on open thyroidectomy patients admitted to the Breast and Thyroid Surgery Department of Shandong Provincial Hospital from January 2020 to December 2023 by reviewing medical records. This study was divided into an experimental group and a control group based on whether a head mounted magnifying glass was used, with the main calculation indicator being changes in PTH levels before and after surgery. This study investigated whether the application of head mounted magnifying glasses had an impact on preoperative and postoperative changes in PTH levels through inter group and self pre - and post control, in order to verify the practical effectiveness of head mounted magnifying glasses in thyroid surgery and provide reasonable suggestions for the selection of subsequent surgical treatment methods.