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NCT ID: NCT03342300 Withdrawn - Toxicity Clinical Trials

Pegylated Liposomal Doxorubicin Versus Pirarubicin Plus Ifosfamide, Dacarbazine in Locally Advanced, Unresectable or Metastatic Soft-tissue Sarcoma

PDVPSTS
Start date: November 6, 2017
Phase: Phase 2/Phase 3
Study type: Interventional

Advanced soft tissue sarcoma patients who have previously recieved anthracyclines might still benefit from doxorubicin, ifosfamide and dacarbazine. However doxorubicin might be stopped using because of chronic cumulative heart toxicity. Several efforts have been made to improve the toxicity profile of conventional anthracyclines, including the use of liposomal encapsulation technology and the development of novel anthracycline analogs,such as pegylated liposomal doxorubicin and pirarubicin. However their actual effectiveness and toxicity have not been studied in prospective trial. The purpose of the study is to investigate whether they are available for this group of patients.

NCT ID: NCT03302221 Withdrawn - Lung Cancer Clinical Trials

Regional Haemodynamic Changes in Radial Artery Assessment With Continuous Pulsed-wave Doppler Ultrasound

Start date: October 15, 2017
Phase: Phase 4
Study type: Interventional

The objective of the trial was to evaluate velocity-associated parameters of pulsed-wave Doppler ultrasound at induction, discharge from the post-anaesthesia care unit and during inspiratory cough in addition to the consumption of phenylephrine during the operation in patients undergoing video-assisted thoracic surgery with three types of anaesthesia management.

NCT ID: NCT03294993 Withdrawn - Blood Flow Indexes Clinical Trials

Doppler Ultrasonography Assessed Vascular Changes Before and After Radial Artery Puncture

Start date: October 1, 2017
Phase: N/A
Study type: Interventional

The investigators designed a study to assess whether there were any blood flow indexes change before and after radial artery puncture with doppler ultrasonography

NCT ID: NCT03267550 Withdrawn - Parkinson Disease Clinical Trials

The Safety of Remote DBS Programming System

Start date: August 8, 2017
Phase: N/A
Study type: Interventional

Remote programming has significant advantages over conventional programming methods on some issues. This research will test the safety of SceneRay remote and wireless DBS programming system.

NCT ID: NCT03252171 Withdrawn - Clinical trials for CAR-T Cell Immunotherapy

CAR-T Cell Immunotherapy for GD2 Positive Glioma Patients

Start date: October 15, 2015
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety and effectiveness of CAR-T cell immunotherapy in treating with GD2 positive glioma patients.

NCT ID: NCT03231475 Withdrawn - NSCLC Stage IV Clinical Trials

Phase I Study of SPH1188-11 in NSCLC

SPH1188-11
Start date: July 21, 2017
Phase: Phase 1
Study type: Interventional

This study will treat patients with advanced NSCLC who have already received at least one course of specific anti-cancer treatment but the tumour has started to re-grow following that treatment. This is the first time this drug has ever been tested in patients, and so it will help to understand what type of side effects may occur with the drug treatment, it will measure the levels of drug in the body, it will also measure the anti-cancer activity. By using these pieces of information together the best dose of this drug to use in further clinical trials will be selected.

NCT ID: NCT03228043 Withdrawn - Colorectal Cancer Clinical Trials

Apatinib for Resectable Colorectal Cancer

Start date: March 1, 2020
Phase: N/A
Study type: Interventional

Objective: To compare the outcome of patients with colorectal cancer who treated with adjuvant therapy or Apatinib with adjuvant therapy postoperatively. Language: English.

NCT ID: NCT03222089 Withdrawn - Clinical trials for Metastatic Colorectal Cancer

Phase II Trial of FOLFOXIGIL Versus FOLFOXIRI as First-line Therapy in Patients With mCRC

Start date: July 20, 2017
Phase: Phase 2
Study type: Interventional

A randomized phase II trial of FOLFOXIRI in Combination With GM-CSF and IL-2 (FOLFOXIGIL) Versus FOLFOXIRI as First-line Treatment for Patients With Metastatic Colorectal Cancer.

NCT ID: NCT03220867 Withdrawn - Healthy Clinical Trials

Bioequivalence Study of Xian Risperdal Tablets Compared With Gurabo Risperdal Tablets Under Fasting and Fed Conditions in Chinese Healthy Participants

Start date: December 11, 2017
Phase: Phase 1
Study type: Interventional

The primary purpose of this study is to assess the bioequivalence of Xian Risperdal compared with Gurabo Risperdal in Chinese healthy participants under fasting and fed conditions.

NCT ID: NCT03190239 Withdrawn - Clinical trials for Advanced Non-squamous Non-small-cell Lung Cancer

Efficacy and Safety of Maintenance Apatinib Combined With Pemetrexed in Advanced Non-squamous Non-small Cell Lung Cancer Patients

XQonc-007
Start date: July 15, 2017
Phase: Phase 2
Study type: Interventional

Lung cancer is a malignant tumor that causes the highest morbidity and mortality, and the main pathological type is non-small cell lung cancer (NSCLC). Most of them present with advanced stage at diagnosis. This design is to study maintenance therapy with pemetrexed plus apatinib after first line induction therapy four cycles for advanced non-squamous non-small-cell lung cancer. XQonc-0007