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NCT06275230 Clinical Trial

Establishment of Human Lung Stem Cell Proliferation System and Organoid Construction in COPD

Chronic Obstructive Pulmonary Disease Clinical Trial

Official title:
Establishment of Human Lung Stem Cell Proliferation System and Organoid Construction in Chronic Obstructive Pulmonary Disease

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT06275230
Other study ID # ZRJY2021-BJ08-02-07
Secondary ID
Status Not yet recruiting
Phase
First received
Last updated
Start date March 20, 2024
Est. completion date December 31, 2025

Study information
Verified date February 2024
Source China-Japan Friendship Hospital
Contact Mingming Deng, MD
Phone +8618801336854
Email isdeng1017@163.com
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The goal of this study is to proliferate human lung stem cell in vitro in order to establish a lung organoid derived from patients with COPD. The main question it aims to answer are: - Can human lung stem cell proliferate in vitro. - Can a lung organoid derived from patients with COPD be established. Participants will be sampled during pulmonary bronchoscope for organoid establishment.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 30
Est. completion date December 31, 2025
Est. primary completion date December 31, 2025
Accepts healthy volunteers No
Gender All
Age group 18 Years to 55 Years
Eligibility Inclusion Criteria: - 1. Age under 55, regardless of gender - 2. Patients with COPD lung disease who are going to undergo bronchoscopic biopsy - 3. No genetic diseases and other respiratory diseases Exclusion Criteria: - Other conditions determined by the investigators to be unsuitable for inclusion, such as difficult sampling, difficult follow-up, and complicated with other serious diseases

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
China-Japan Friendship Hospital

Outcome
Type Measure Description Time frame Safety issue
Primary Number of Patients completed bronchoscope. 1 day
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