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Clinical Trial Summary

This is an observational study of 600 participants to further define the nature of early chronic obstructive pulmonary disease (COPD) in younger, at-risk individuals. The study has three main goals: - To use CT scan imaging to identify which smokers will develop COPD. - To identify biomarkers predictive of smokers that will develop COPD. - To determine if sputum (phlegm) can be analyzed to predict which smokers will develop COPD. Procedures (methods): All participants will undergo study related questionnaires assessing medical history, smoke exposure and use, medication use, social and behavioral health, pulmonary symptoms, food frequency, and will provide nasal swab, blood, stool, and urine samples, pulmonary function testing to determine function, sputum induction to provide a sputum sample for airway biospecimen analysis, and CT imaging of the lungs.

Clinical Trial Description


Study Design

Related Conditions & MeSH terms

NCT number NCT05033990
Study type Observational
Source Weill Medical College of Cornell University
Contact Lori A Bateman, MS
Phone 9199623266
Email [email protected]
Status Not yet recruiting
Start date September 2021
Completion date April 2025

See also
  Status Clinical Trial Phase
Active, not recruiting NCT04166812 - Change in Airway Peripheral Tone in COPD