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Contraception clinical trials

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NCT ID: NCT02905513 Completed - Contraception Clinical Trials

An Intervention Delivered by App Instant Messaging to Increase the Acceptability of Effective Contraception Among Young People in Tajikistan

Start date: November 16, 2016
Phase: N/A
Study type: Interventional

This randomised controlled trial will establish the effect a contraceptive intervention delivered by mobile phone app instant messaging on the acceptability of effective contraception in Tajikistan. Woman and men aged 16-24 will be randomised to have access to the Tajik Family Planning Alliance's sexual and reproductive health app (control) or the app plus 0-3 instant messages a day for 4 months (intervention). Participants will complete a questionnaire at baseline and 4 months.

NCT ID: NCT02905461 Completed - Contraception Clinical Trials

An Intervention Delivered by Text Message to Increase the Acceptability of Effective Contraception Among Young Women in Palestine

Start date: December 8, 2016
Phase: N/A
Study type: Interventional

This randomised controlled trial will establish the effect a contraceptive intervention delivered by mobile phone text message on the acceptability of effective contraception in Palestine. Woman aged 18-24 will be randomised to receive 0-3 text messages a day for 4 months (intervention) or a monthly text message not about contraception (control). Participants will complete a questionnaire at baseline and 4 month follow-up.

NCT ID: NCT02904629 Completed - Pregnancy Clinical Trials

Evaluation of Respecting the Circle of Life on Pregnancy Prevention Outcomes Among American Indian Adolescents

TPP
Start date: May 2016
Phase: N/A
Study type: Interventional

The objective of this research study is to evaluate a culturally tailored sexual and reproductive health intervention among American Indian (AI) youth. Specifically, the investigators aim to evaluate the impact of "Respecting the Circle of Life: Mind, Body and Spirit" on knowledge, attitude and behavioral outcomes associated with risk for unprotected sex, sexually transmitted infection (STI) and unintended pregnancy through a randomized controlled trial on the White Mountain Apache (WMA) reservation. The investigators will examine whether the RCL intervention effectively reduces risky sexual behavior among AI adolescents (11-19 years old), with long term goals of reducing teen pregnancy and incidence/prevalence of STIs. The evaluation will focus on well-established intermediate outcomes/risky sexual behaviors that predict long-term impact on teen pregnancy and STI incidence.

NCT ID: NCT02882191 Completed - Contraception Clinical Trials

Evaluation of the Efficacy and Safety of LevoCept

Start date: November 2016
Phase: Phase 2
Study type: Interventional

To evaluate the effectiveness, device placement, safety, and tolerability of LevoCept to support commencing a Phase III Clinical Study

NCT ID: NCT02874248 Completed - Contraception Clinical Trials

E4/DRSP Single and Multiple Dose PK and Early QT Study

Start date: May 2016
Phase: Phase 1
Study type: Interventional

This study is conducted to evaluate the effect of single and multiple therapeutic and supratherapeutic oral doses of E4/DRSP combinations on PK parameters, safety, tolerability and on cardiac repolarization, as detected by QT interval corrected with Fridericia's formula (QTcF).

NCT ID: NCT02866279 Completed - Contraception Clinical Trials

Immediate Postpartum Contraceptive Implant Placement and Breastfeeding Success in Women at Risk for Low Milk Supply: A Non-inferiority Trial

Start date: November 2016
Phase: N/A
Study type: Interventional

The investigators goal is to measure the impact of timing of postpartum contraceptive implant insertion on breastfeeding success and duration and to explore women's experiences with and attitudes towards contraceptive and breastfeeding counseling in the peripartum time period

NCT ID: NCT02859337 Completed - Obesity Clinical Trials

Effectiveness of Orally Dosed Emergency Contraception in Obese Women - UPA

UPA-Obesity
Start date: May 30, 2017
Phase: Phase 4
Study type: Interventional

Obese women are significantly more likely than their normal BMI counterparts to experience failure of orally-dosed emergency contraceptives. Our preliminary data provides evidence for testing a dose escalation strategy in an effort to provide improved efficacy from orally-dosed emergency contraceptives in obese women. More data is needed regarding emergency contraception containing ulipristal acetate. The overall project will be focused on both levonorgestrel (LNG) - and ulipristal acetate (UPA)-containing emergency contraception but this protocol registration is for the UPA aspect of the study procedures.

NCT ID: NCT02852681 Completed - Contraception Clinical Trials

Effect of Food on the Bioavailability of 15 mg Estetrol/3 mg Drospirenone Tablets in Healthy Female Volunteers

Start date: August 2015
Phase: Phase 1
Study type: Interventional

This single-center, open-label, randomized, balanced, single-dose, two-treatment, two-period, two-sequence crossover study was conducted under medical supervision in 28 healthy female volunteers.

NCT ID: NCT02852265 Completed - Contraception Clinical Trials

Nexplanon and Combined Oral Contraceptive (COC) Combined Use Study

NexTOC
Start date: September 15, 2016
Phase: Phase 4
Study type: Interventional

Women currently using or starting a combined oral contraceptive will be offered study enrollment. Study subjects will have a Nexplanon placed and followed for 6 months to evaluate if they continue the COC, continue the implant, or both, and to assess adverse events and bleeding patterns.

NCT ID: NCT02842177 Completed - Contraception Clinical Trials

Evaluation of a Novel Technique for Intrauterine Contraceptive Devices Insertion

Start date: January 2016
Phase: N/A
Study type: Interventional

The intrauterine devices are a safe, reliable, long-acting and reversible contraceptive method. It is also sound safe and cheap contraceptive methods available and is nearly maintenance free for up to 10 years. The fear and the pain associated with intrauterine devices insertion consider barriers to using this contraception method, this is because that the mucosal lining of female genital tract is highly sensitive to touch and pain. However; most of small procedures done in this sensitive area are performed without analgesia. The pain during intrauterine devices insertion is due to application of the tenaculum , traction of the cervical canal, passing the uterine sound, insertion of the intrauterine devices through the cervix, and irritation of the endometrial lining by the intrauterine devices . Previous studies have reported different lines to decrease pain during intrauterine device insertion starting by simple methods such as pre-insertion ibuprofen use, intracervical or intrauterine lidocaine and misoprostol up to paracervical blocks. Previous studies, in literature, have found that the most painful steps during intrauterine devices insertion were uterine sounding then intrauterine device insertion itself, followed by tenaculum placement. One recent study addressed pain effect using an atraumatic vulsellum and a single-tooth tenaculum on pain perception during intrauterine devices and found no difference in reported pain.