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Contraception clinical trials

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NCT ID: NCT03088722 Completed - Contraception Clinical Trials

A Study Comparing Implant Provision by Community Health Extension Workers With Nurses and Midwives in Nigeria

Start date: January 1, 2016
Phase: N/A
Study type: Interventional

This proposed study, to be run by Marie Stopes International Organisation Nigeria (MSION) will investigate whether Community Health Extension Workers (CHEWs) in Nigeria can insert and remove contraceptive implants to the same level of safety and quality as a nurse or midwife, and whether this is acceptable to their clients and colleagues. The study will also document feasibility issues which would be relevant to any future national programmatic scale-up.

NCT ID: NCT03088397 Completed - Contraception Clinical Trials

Effectiveness of a Patient Decision Aid in Immediate Postpartum Contraceptive Counseling

POCO
Start date: January 2017
Phase: N/A
Study type: Interventional

Effective physician-patient communication in postpartum contraceptive counseling is essential for patients to meet their contraceptive needs and reduce the risk of rapid repeat pregnancies. This project will utilize a patient decision aid to facilitate shared decision making in the immediate postpartum setting, assess the effectiveness of such aid in "decision quality" and "decision-making process quality", and observe its effects on contraceptive choice mix at the time of discharge.

NCT ID: NCT03075956 Completed - Contraception Clinical Trials

Safety, Tolerability and Pharmacokinetics of Estetrol (E4) After Single and Multiple Oral Doses in Healthy Female Volunteers

Start date: January 31, 2017
Phase: Phase 1
Study type: Interventional

Estetrol (E4) is being developed in two indications supporting women health care: first E4 is combined with a progestin, [drospirenone (DRSP)] and is used as a new combined oral contraceptive (COC) for the prevention of pregnancy and secondly, E4 is used alone as new hormone replacement therapy (HRT) for the treatment of menopause related symptoms. The current clinical trial is designed to collect more detailed information about the PK profile, safety and tolerability of different dosages of E4, given orally as a solid tablet.

NCT ID: NCT03074045 Completed - Contraception Clinical Trials

LCS16 vs. COC User Satisfaction and Tolerability Study

Start date: March 13, 2017
Phase: Phase 3
Study type: Interventional

To evaluate user satisfaction in young nulliparous and parous women (18-29 years of age [inclusive]), using LCS16 compared to a COC over a period of 12 months.

NCT ID: NCT03067272 Completed - Contraception Clinical Trials

Pilot Bi-Lateral Tubal Occlusion Trial for Female Permanent Contraception

BLOC
Start date: March 15, 2017
Phase: N/A
Study type: Interventional

Prospective, multi-center, pilot study evaluating the safety of the FemBloc® Permanent Contraceptive System for female sterilization in preventing pregnancy.

NCT ID: NCT03065842 Completed - Pregnancy Clinical Trials

A Pre and Post Test Intervention Design to Prevent Abortion and Contraceptive-use Stigma Among School Youths in Kenya

SAC
Start date: February 5, 2017
Phase: N/A
Study type: Interventional

In many low-income countries, unsafe abortion is recognized as a leading cause of maternal morbidity and mortality. Social stigma surrounding abortion and contraceptive use plays a critical role in the social, medical, and legal marginalization of abortion and contraceptive services. Though this stigma is pervasive and threatens women's health, it is not well understood how it can be reduced. The Stigmatizing Attitudes, Beliefs and Actions Scale (SABAS) was designed in 2013, to measure abortion stigma at individual and community level. Objective: I) to conceptualize abortion stigma among; health care providers, secondary school teachers and students, and II) to determine if a school based intervention targeting stigma specifically faced by girls when accessing abortion and contraceptive services, compared to usual standards, will decrease related stigma and increase contraceptive use among students, who are sexually active. Design, Setting, Participants: I) Focus group discussions (FGD) with service providers at YFC (n=12), secondary school teachers (n=16) and secondary school students (n=20), and II) a quasi-experimental pre- and post-intervention study, targeting 800 secondary school students (14-20 y), in Kisumu, Kenya. Two schools will be assigned; one interventions unit (n=400 students) and one control unit (n=400 students). The schools are similar according to the study site, size and academic standards. The region is chosen because of its low rate of contraceptive use, and high rate of teen pregnancy and of unsafe abortions. Standard deviation is the measure of dispersion or variability in the data. The sample size of 400 is based on a previous study and will give a power of 80% to detect differences (95% Cl) between the two groups. Intervention: An abortion- and contraceptive-use stigma reduction intervention (1-month program), capturing negative stereotypes about women that are associated with abortion and contraceptive use. Main Outcome: Abortion-stigma reduction. Secondary outcome: Contraceptive-use stigma reduction. Measured at baseline (pre-test), and post-test at 1- and 12-months, by using the validated SABA-scale. Analyses: Qualitative content analysis and repeated measures, ANOVA. Funded by: The Swedish Research Council for Health, Working Life and Welfare 2015-01194, and The Swedish Research Council 2016-05670

NCT ID: NCT03058978 Completed - Contraception Clinical Trials

Assessing Ovarian Function During Prolonged Implant Use

Start date: March 1, 2017
Phase:
Study type: Observational

The study will evaluate how the ovaries may be functioning while using the the Implanon®/Nexplanon® during the three years beyond the FDA approved duration. Ovarian function will be assessed with weekly serum progesterone levels. Participants will undergo weekly venipuncture for a total of four draws. Participants will be followed for 30 days.

NCT ID: NCT03049592 Completed - Diabetes Clinical Trials

High-risk Obstetrical Patient Intervention Utilizing the Contraceptive CHOICE Project Script

HIBISCUS
Start date: July 2016
Phase: N/A
Study type: Interventional

High-risk obstetrical patient Intervention to promote Birth Interval Spacing utilizing the Contraceptive CHOICE project script to reduce Unintended Subsequent pregnancies (HIBISCUS) is a collaborative study utilizing qualitative methods to assess the acceptability including a family planning specialist's postpartum contraception counseling during and after prenatal care among Latina obstetric women with pre-gestational diabetes. The investigators will compare the effectiveness of HIBISCUS versus usual contraceptive counseling on Long-Acting Reversible Contraception (LARC) use at 3 months postpartum.

NCT ID: NCT03034057 Completed - Contraception Clinical Trials

Sayana Press UK Self-Injection Study

Start date: August 23, 2017
Phase: Phase 4
Study type: Interventional

A one-year evaluation of Sayana Press self injection in women of reproductive age in the United Kingdom (UK).

NCT ID: NCT03031795 Completed - Contraception Clinical Trials

Oral Ketorolac for Pain Relief During IUD Insertion

Start date: July 2014
Phase: Phase 4
Study type: Interventional

Ketorolac is a non-steroidal anti-inflammatory drug (NSAID), similar to ibuprofen but it is used to treat more severe pain. Ketorolac (Trade name: Toradol) is typically used after surgical procedures. When taken orally, it should not cause sedation. The purpose of this study is to determine if oral ketorolac is effective at reducing pain during IUD placement versus a placebo tablet.