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Condylomata Acuminata clinical trials

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NCT ID: NCT00449982 Completed - Clinical trials for Condylomata Acuminata

Efficacy and Safety Study of Polyphenon E to Treat External Genital Warts

Start date: July 2003
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate the clinical efficacy, safety and tolerability of a Polyphenon E Ointment 10% and a Polyphenon E Ointment 15% in the treatment of external genitial warts in male and female patients.

NCT ID: NCT00365443 Withdrawn - Cervical Cancer Clinical Trials

Broad Spectrum HPV Vaccine Tolerability, Immunogenicity, and Efficacy Study (V502-003)

Start date: October 2006
Phase: Phase 2
Study type: Interventional

This study is to evaluate an investigational vaccine with the following objectives: (1) To demonstrate prevention of cervical, vulvar, and vaginal cancers and related precancers, external genital lesions, and persistent infection caused by the HPV types in the study vaccine, (2) To demonstrate that the vaccine is well-tolerated in women, (3) To evaluate vaccine immune responses in women. This is an early phase trial and some specific protocol information is proprietary and not publicly available at this time. (Full information is available to trial participants).

NCT ID: NCT00189293 Completed - Genital Warts Clinical Trials

Study of Imiquimod Cream Prior to Ablative Therapy in External Ano-Genital Warts

Start date: June 2005
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the recurrence rate following total clearance of external genital warts (EGWs) when clearance has been obtained by imiquimod (3 applications per week for 4 weeks) followed by ablative therapy (laser or electrocautery therapy) with that from just ablative therapy treatment alone.

NCT ID: NCT00092534 Active, not recruiting - Cervical Cancer Clinical Trials

Cervical Intraepithelial Neoplasm (CIN) in Women (Gardasil) (V501-015)

FUTURE II
Start date: June 14, 2002
Phase: Phase 3
Study type: Interventional

The primary purpose of the study is to determine if GARDASIL™ (V501) is able to prevent cervical cancer.

NCT ID: NCT00092482 Completed - Cervical Cancer Clinical Trials

Immunogenicity Bridge Between an Investigational Monovalent Vaccine and the Equivalent Component of Gardasil (V501) a Quadrivalent Vaccine (V501-012)(COMPLETED)

Start date: June 28, 2002
Phase: Phase 3
Study type: Interventional

The purpose of the study is to determine if an investigational vaccine with a single component develops an immune response that is similar to the equivalent investigational vaccine with four components to reduce cervical disease.

NCT ID: NCT00090285 Completed - Clinical trials for Condylomata Acuminata

An Investigational Study of Gardasil™ (qHPV Vaccine) in Reducing the Incidence of Anogenital Warts in Young Men (V501-020)

Start date: September 3, 2004
Phase: Phase 3
Study type: Interventional

This study was conducted to demonstrate that Gardasil™ (quadrivalent human papillomavirus [qHPV] vaccine) 1) is well tolerated in young men, 2) reduces incidence of external genital lesions in young men, 3) reduces the incidence of anal intraepithelial neoplasia (AIN) or anal cancer in men having sex with men (MSM), and 4) reduces incidence of Human Papillomavirus (HPV) infection in young men. In the 7-month Base Study participants received randomly assigned qHPV vaccine or placebo at Day 1, Month 2, and Month 6. Base Study follow-up continued through Month 36. In Extension 1 (EXT1), participants who received placebo or an incomplete qHPV vaccine regimen in the Base Study were offered qHPV vaccine. Participants were followed in EXT1 for 7 months. In Extension 2 [LTFU (EXT2)], long-term effectiveness, immunogenicity, and safety of qHPV vaccine were followed up to 10 years following study enrollment. Participants who received ≥1 dose of qHPV vaccine in the Base Study or EXT1 were eligible to enroll in LTFU (EXT2).