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Complications clinical trials

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NCT ID: NCT01465945 Completed - Post-operative Pain Clinical Trials

Study of Unsutured Versus Sutured Closure of Rectal Defects After Rectal Lesion Excisions Using Transanal Endoscopic Microsurgery

Start date: March 2012
Phase: N/A
Study type: Interventional

Transanal Endoscopic Microsurgery (TEM) is a minimally invasive technique used to remove rectal tumours. After the tumour has been removed from the rectum, the surgeon has a choice to close the defect or leave the defect open and naturally close. Currently, both options are accepted as standard care. Leaving the defect open to close naturally has some possible advantages, including shortened operation time and similar rates of postoperative complications. However, there is some concern that not surgically closing the defect may lead to more postoperative pain and delay in recovery. The study will be a double blind randomized controlled trial and determine whether patients who have rectal wall defect sutured closed have less post-operative pain compared to patients whose defect is left open.

NCT ID: NCT01435876 Completed - Complications Clinical Trials

Surgery and Convergence Insufficiency Intermittent Exotropia

Start date: May 2006
Phase: N/A
Study type: Interventional

This trial aims to determine which treatment modality is better for treatment of the convergence insufficiency subtype of intermittent exotropia.

NCT ID: NCT01420757 Completed - Postoperative Pain Clinical Trials

Laparoscopic Versus Open Incisional Hernia Repair

COLIBRI
Start date: May 1999
Phase: Phase 3
Study type: Interventional

Primary closure of incisional hernia without the use of a mesh shows recurrence rates of up to 54%. If a mesh is used, the defect can be closed tension-free. Using this method, recurrence rates have been reduced to 8-21%. Laparoscopic correction of incisional hernia is a relatively new technique in which the mesh is positioned intraperitoneally. Research has shown that this procedure is technical feasible and may have benefits for the patients. The ongoing debate about the merits of endoscopic versus open incisional hernia repair prompts the need for a level 1 randomized controlled trial.

NCT ID: NCT01267552 Completed - Breast Cancer Clinical Trials

Study of Axillary Lymphadenectomy Without Drainage for Breast Cancer

Start date: July 2000
Phase: Phase 2/Phase 3
Study type: Interventional

To study the safety of not draining the axilla, after breast conserving surgery and full axillary lymphadenectomy.

NCT ID: NCT01247155 Completed - Complications Clinical Trials

First Postoperative Day Review After Uneventful Phacoemulsification

Start date: n/a
Phase: N/A
Study type: Observational

The purpose of this randomized trial was to examine the value of the review on the first postoperative day after uneventful phacoemulsification cataract surgery.

NCT ID: NCT01081977 Completed - Anemia Clinical Trials

Effect of Timing of Umbilical Cord Clamping on Haematological and Clinical Outcomes of Infants

Start date: August 2008
Phase: Phase 2
Study type: Interventional

In developing countries up to 50% of children become anemic by 12 months of age(1. Iron deficiency anemia is a major risk factor for neonatal and infantile mortality and morbidity in Pakistan. It has detrimental effects on neurodevelopment of infants and may be irreversible even after iron therapy(2). Type of cost effective interventions during perinatal period for prevention of anemia in later infancy is limited. Delayed cord clamping has a beneficial effect on prevention of anemia in later infancy because of increased iron stores at birth(3. However there are controversies in incorporating delayed cord clamping practice in the management of third stage of labour globally(4) Paucity of national guidelines and lack of substantial data in Pakistan on this topic strongly necessitates such study trials. This study may contribute to develop a protocol on the timing of cord clamping which will be cost effective in prevention of iron deficiency anemia in the investigators infantile population. The investigators will conduct a randomized controlled trial and the investigators hypothesis is that delayed cord clamping will result in higher hemoglobin (Hb), hematocrit (Hct) and ferritin at third month as compared to early cord clamping. OBJECTIVES: A- Primary: 1. To study the effect of timing of umbilical cord clamping on hemoglobin (Hb), Hematocrit (Hct) at birth, 48 hours and Hb, Hct and ferritin at three months of age. 2. To study the effect of timing of umbilical cord clamping on short term clinical profile of neonates like jaundice, respiratory distress, anemia, polycythemia etc. during fist 24 to 48 hours of life. B- Secondary: To assess whether delayed cord clamping is associated with undesirable effects on mothers followed till 48 hours postpartum.

NCT ID: NCT01080547 Completed - Quality of Life Clinical Trials

Study Comparing Conventional and Fast Track Multi-Discipline Treatment Interventions for Colorectal Cancer

Start date: March 2010
Phase: Phase 3
Study type: Interventional

A new notion"Fast Track Multi-Discipline Treatment" for colorectal cancer is thought with several benefits such as shorter hospitalization stay and less costs. This randomized study aims to compare the differences between conventional and Fast Track Multi-Discipline Treatment for colorectal cancer in hospitalization day, complications, costs and quality of life.

NCT ID: NCT01072487 Completed - Hypoxemia Clinical Trials

Capnography During Colonoscopy

ColoCap
Start date: February 2010
Phase: Phase 3
Study type: Interventional

In the study the value of capnography for avoiding complications during sedation for colonoscopy is evaluated.

NCT ID: NCT01072474 Completed - Hypoxemia Clinical Trials

Capnography During ERCP

EndoBreath
Start date: February 2010
Phase: Phase 3
Study type: Interventional

In the study the value of capnography for avoiding complications during sedation for ERCP is evaluated.

NCT ID: NCT01042223 Completed - Complications Clinical Trials

Laryngomalacia Exposed

Start date: January 2006
Phase:
Study type: Observational

Laryngomalacia is the most common congenital laryngeal anomaly and the most frequent cause of stridor in infants and children. Symptoms usually appear within the first 2 weeks of life. Its severity increases up to 6 months. 15-60% of infants with laryngomalacia have synchronous airway anomalies.