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Colonoscopy clinical trials

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NCT ID: NCT04349150 Completed - Colonoscopy Clinical Trials

Virtual Reality Alternative to Pharmacological Sedation During Colonoscopy

Start date: May 10, 2019
Phase: N/A
Study type: Interventional

Colonoscopy patients will be fitted with a virtual reality head-mounted display, and virtual experiences will be initiated prior to colonoscope insertion. Colonoscopy will be initiated without standard sedatives and narcotics. The colonoscopy will proceed with the subject using virtual reality distraction instead of pharmacological sedation for as long as s/he would like. Standard sedatives and narcotics will be administered upon participant request at any time during the procedure. Questionnaires will be administered to the subject and the endoscopist after each procedure to assess the acceptability of use of virtual reality in the colonoscopy setting.

NCT ID: NCT04325139 Completed - Colonoscopy Clinical Trials

External Validation of a Predictive Model for Bowel Preparation in Patients Undergoing Colonoscopy

Start date: March 23, 2020
Phase:
Study type: Observational [Patient Registry]

Bowel preparation is closely lined to the quality of colonoscopy, inadequate bowel preparation (IBP) could lead to higher miss rate of adenomas, patients' discomfort and higher health expense. For the patients with possible IBP before the examination, it may be better to cancel the colonoscopy and repeat bowel preparation through modified or enhanced strategies. This study aimed to externally validate the efficiency of a procedure-based model in predicting inadequate bowel preparation

NCT ID: NCT04316858 Completed - Colonoscopy Clinical Trials

Randomized Trial Comparing Carbonated Drink With Water as a Solvent for Colonoscopy Solution

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

This prospective randomized trial will be conducted in all patients undergoing elective colonoscopies from February 2020 to August 2020 in Dowites Operation Theater Endoscopy suite by surgical unit III, Civil Hospital Karachi. Patient will be select randomly based on inclusion criteria. Patients will be advised to take 90ml of sodium phosphate in 800ml solvent ( zero calorie soft drink and water). Patients will be nil per oral from midnight aside from clear liquids. Serum electrolytes, urea, creatinine will be measured after and before bowel preparation. Bowel preparation will be assessed by consultant during endoscopy. Questionnaire will be filled by PI for palatability, tolerance of solution, adverse effects, and willingness to repeat the preparation.

NCT ID: NCT04310332 Completed - Colonoscopy Clinical Trials

1L- vs. 4L-PEG for Bowel Preparation Among Inpatients.

Start date: February 1, 2019
Phase:
Study type: Observational

Background and aims: Inpatients are at high risk for inadequate colon cleansing. Experts recommend 4L-polyethylene-glycol (PEG) solution because of its effectiveness and safety profile. A higher colon cleansing adequacy rate for a hyperosmolar 1L-PEG plus ascorbate prep has been recently reported in an observational study among more than 1,000 inpatients. Thus, the present study is aimed at determining whether 1L-PEG outperforms 4L-PEG among inpatients, through a propensity score-matching between the two groups in order to correct for confounders.

NCT ID: NCT04290715 Completed - Colonoscopy Clinical Trials

Development and Validation for Predicting Inadequate Bowel Preparation

Start date: January 1, 2020
Phase:
Study type: Observational

High-quality colonoscopy is considered the gold standard for the detection and prevention of colorectal cancer, and its efficacy is predicated on optimal colon cleansing.However, about 18%-35% of patients were still reported to suffer inadequate bowel preparation. Although several predictive models exist, the current guideline indicates that there is insufficient evidence to recommend the use of a predictive model for clinical practice.

NCT ID: NCT04258800 Completed - Pain Clinical Trials

Impact of Music in Colonoscopy

ColoRelaxTone
Start date: November 12, 2019
Phase: N/A
Study type: Interventional

The study examines the impact of music during colonoscopy on sympathetic - autonomic nervous system, whose activity is operationalized by biopotentials signals. The music is chosen by the patients themselves. The Null hypothesis: The comparison of the sympathetic - autonomic nervous system (operationalized by biopotentials) intensity between colonoscopy "with" vs. "without" music is not significant. Alternative hypothesis: The comparison of the sympathetic - autonomic nervous system intensity is significantly higher in colonoscopy "without" music vs. "with" music.

NCT ID: NCT04246632 Completed - Colonoscopy Clinical Trials

CapsoCam® Colon Capsule Endoscope (CCE) Compared to Colonoscopy (OC)

Start date: January 25, 2020
Phase: N/A
Study type: Interventional

This non-significant risk pilot study is designed to evaluate safety and performance of the CapsoCam® Colon capsule endoscope in patients who meet the eligibility criteria and are scheduled for colonoscopy.

NCT ID: NCT04214301 Completed - Colonoscopy Clinical Trials

An Open-Label Preference Evaluation of BLI800

Start date: September 24, 2019
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate patient experience ratings of BLI800 in adult patients undergoing colonoscopy.

NCT ID: NCT04101097 Completed - Colonoscopy Clinical Trials

Training and Validation of Models of Factors to Predict Inadequate Bowel Preparation Colonoscopy

Start date: September 3, 2019
Phase:
Study type: Observational

The rate of adequate bowel preparation is one of important quality indicators of colonoscopy. Inadeqaute bowel preparation negatively affects the outcomes of colonoscopy. If patients with inadequate bowel preparation were identified before the procedure, enhanced strategy could be offerred to achieve better bowel cleasing. Currently, there were three predicting models of inadequate bowel preparation eatablished based on patient-related factors. It remains unclear which model perfroms better in predicting bowel preparation quality. Futhermore, althought those predicting models only composing of patients-related factors are useful for identifing high-risk patients, the preparation-related factors may also be valuable for prediciting inadeqaute bowel preparation before the procedure of colonoscopy. This study aimed: 1) to compare the values of three availlable models (based on patient-related factors) in predicting inadeqaute bowel preparation in a prospective, multicentered cohort of patients undergoing colonoscopy; 2) to investigate whether a new model based on preparation-related or a combined model based on patient-related and preparation-related factors is comparable to previous models based on patient-related factors.

NCT ID: NCT04086706 Completed - Colonoscopy Clinical Trials

Retroflexion In The Ascending Colon Is A Costless Endoscopic Maneuver Increasing Adenoma Detection Rate

Start date: June 1, 2017
Phase:
Study type: Observational

Missing polyps during colonoscopy is considered an important factor for interval cancer appearance especially in the ascending colon (AC). Aim of the study: To evaluate the contribution of retroflexion to adenoma detection in the AC. Patients-Methods: Prospective observational study included consecutive patients with complete colonoscopy between June 2017 and June 2018. The AC was examined in two phases. The first phase included two forward views from the hepatic flexure to the cecum and the second phase a retroflexion in the cecum, inspection till the hepatic flexure then redressing to forward view and reinsertion to the cecum.