Clinical Trial Details
— Status: Completed
Administrative data
| NCT number |
NCT02672930 |
| Other study ID # |
230 |
| Secondary ID |
|
| Status |
Completed |
| Phase |
|
| First received |
|
| Last updated |
|
| Start date |
July 2015 |
| Est. completion date |
July 2017 |
Study information
| Verified date |
September 2020 |
| Source |
Haseki Training and Research Hospital |
| Contact |
n/a |
| Is FDA regulated |
No |
| Health authority |
|
| Study type |
Observational [Patient Registry]
|
Clinical Trial Summary
Hyperkalemia is a common problem in the emergency services and one of the life threatening
metabolic emergencies. Calcium, insulin, beta adrenoceptor agonists, bicarbonate, diuretics,
sodium polystyrene sulfonate and lastly dialysis are advised in treatment. Especially,
avoiding evolution of serious arrythmias and iv calcium using in the treatment of occured
electrocardiogram (ECG) abnormalities, there is not sufficient level of survey in the
literature. So the aim of this study was to evaluate administration of iv calcium efficiency
on vital signs and ECG.
Description:
Hyperkalemia is a common problem in the emergency services and one of the life threatening
metabolic emergencies. Serious hyperkalemia is mostly seen in patients who have known chronic
renal failure or end stage renal disease, and also new diagnosis of acute renal failure can
be appear with serious hyperkalemia. Paresthesia and weakness which is proceeded to flask
paralysis can be observable, sharp ''T'' waves (the repolarization and relaxation of the
ventricles), diminution of ''P'' waves (atrial depolarisation and contraction), long ''PR''
intervals (time frame from the beginning of atrial depolarization to the beginning of
ventricular depolarization), or elongated ''QRS'' complexes (depolarisation and contraction
of the ventricles), ''ST'' segment (end of the QRS complex to the beginning of the T wave)
elevation, and serious ventricular arrythmias can be seen in electrocardiography. Calcium,
insulin, beta adrenoceptor agonists, bicarbonate, diuretics, sodium polystyrene sulfonate and
lastly dialysis are advised in treatment. Especially, avoiding evolution of serious
arrythmias and İv calcium using in the treatment of occured ''ECG'' abnormalities, there is
not sufficient level of survey in the literature. The group of Cochrane stated in systematic
assessment report, which is published in 2005 about IV calcium administration, available
dates are based on anecdotal and animal experiments. And in the researches that we have done,
we did not find clinical human studies showing the benefits of calcium administration beyond
the delivery of case reports . The aim of this study was to evaluate administration of İv
calcium efficiency on vital signs and ECG.
