Chronic Pain Clinical Trial
Official title:
rTMS for the Treatment of Chronic Pain in GW1 Veterans
This study was designed to evaluate the effect of repetitive Transcranial Magnetic Stimulation (rTMS) in the resolution of Chronic Pain. Participants will be Veterans from the first Gulf War (GW1) who often suffer from chronic pain problems.
A number of studies have been conducted on the health of Veterans deployed to Iraq during
GW1. The focus of these studies has been primarily to define the nature of symptoms and
symptom clusters and to determine if evidence supports the definition of a new unique
illness. Most noteworthy is the "Iowa Study", a cross-sectional study of 3,695 Veterans from
Iowa consisting of those who were and were not deployed in GW1. In telephone interviews the
Gulf War deployed Veterans reported approximately twice the number of symptoms compared to
those who were not deployed.
The often ambiguous and seemingly treatment resistant symptoms presented by GW1 Veterans
represent a challenge to the Veteran's Affairs Health Care System on two fronts; efficacy in
treatment and cost. In particular, unlike most medical conditions which can be diagnosed by
objective medical findings, pain is a subjective experience (International Association for
the Study of Pain, 1994). Therefore the investigators propose to engage in a clinical trial
of rTMS in chronic pain that occurs in the context of multiple medical symptoms in the GW1
population. The symptom category approach will be applied with the restriction that enrolled
GWI diagnosed patients will have symptoms of chronic pain as outlined in the musculoskeletal
category and at least two additional symptoms.
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