Chronic Obstructive Pulmonary Disease Clinical Trial
Official title:
Does Nocturnal Continuous Positive Airway Pressure Use Improves Sleep Quality in Chronic Obstructive Pulmonary Disease Patients?
Static hyperinflation is frequent in Chronic obstructive pulmonary disease (COPD) , resulting
in increased end expiratory lung volume and positive end expiratory pressure (PEEPi) at the
end of a normal expiration.
Static hyperinflation worsens the work of breathing is increases patient's dyspnea.
The application of a continuous positive airway pressure (CPAP) has been shown to improve
static hyperinflation and to decrease the work of breathing.
Sleep is deteriorated in COPD patients, and causal factors includes static hyperinflation.
The purpose of our study is to assess the effect of nocturnal CPAP on sleep quality and
functional respiratory parameters.
Chronic obstructive pulmonary disease (COPD) is characterized by an airflow obstruction,
inducing a flow limitation. As a consequence, we observe in these patients an increased end
expiratory lung volume and a positive end expiratory pressure (PEEPi) at the end of a normal
expiration.
Patients are breathing at higher pulmonary volumes: this is the concept of static
hyperinflation.
This worsens the breathing pattern because in this situation, the work of breathing is
increased such that dyspnea increases.
The application of a continuous positive airway pressure (CPAP) has been shown to improve
static hyperinflation and to decrease the work of breathing.
Sleep is deteriorated in COPD patients, and causal factors includes static hyperinflation,
cough, depression. Moreover, normal physiological changes occuring during sleep in COPD
patients are leading to deterioration of gaseous exchanges. The purpose of our study is to
assess the effect of nocturnal CPAP on sleep quality and functional respiratory parameters.
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