Chronic Kidney Disease Clinical Trial
Official title:
A Phase 2a, Prospective, Randomized, Double-blind, Placebo-controlled Multicenter Study to Evaluate the Safety and Efficacy of Atrasentan on Reducing Albuminuria in Type 2 Diabetic Nephropathy Subjects Who Are Currently Being Treated With an Renin-Angiotensin System Inhibitor
The study objective is to investigate the effects of three low doses of atrasentan on urinary
albumin/creatinine ratio (UACR) levels in subjects with Type 2 diabetic nephropathy.
Patients with Type 2 diabetes with nephropathy must be receiving a renin-angiotensin system
inhibitor, such as an Angiotensin converting enzyme inhibitor (ACEi) or an Angiotensin II
Receptor Blocker (ARB) for participation in this study. ACEi and ARB treatment are the
standard of care for the management of proteinuria in Chronic Kidney Disease (CKD) patients.
n/a
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