Cesarean Section; Shivering Clinical Trial
Official title:
Dosage of Intrathecal Hyperbaric Bupivacaine and the Incidence of Post Spinal Shivering in Cesarean Section: is There a Relation?
Shivering is very common after spinal anaesthesia. Many studies have investigated the role of adding adjuvants to the local anaesthetics to decrease the incidence of post-spinal shivering. Non of the studies n the literature review have investigated the role of different dose of local anaesthetic alone in reducing the incidence of post-spinal shivering. In the present study the investigators aimed to compare the effect of different local anaesthetic dose in reducing post-spinal shivering.
After approval of the ethics committee, department of anaesthesia, Menoufia University and
written informed consent, a hundred full-term pregnant ladies undergoing elective cesarean
section were enrolled in this study.
The pregnant ladies were randomly assigned using a computerised software to one of two
groups, low dose bupivacaine (LB) and high dose bupivacaine (HB), 50 patients each according
to bupivacaine dose. Group LB received low dose bupivacaine (8 mg hyperbaric bupivacaine)
Group HB received high dose bupivacaine (10 mg hyperbaric bupivacaine).
Vital signs including heart rate and mean arterial blood pressure intra-operatively until the
end of surgery.
The severity of shivering was the primary endpoint. Shivering was graded using a scale: 0, no
shivering; 1, piloerection but no visible muscle activity; 2, muscular activity in one group
of muscle; 3, muscular activity in more than one muscle group but not generalized movement;
and 4, shivering involving the movement of the whole body. Shivering score was recorded for
the whole study period.
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03008850 -
Shivering Prevention During Cesarean Section by Intrathecal Injection of Magnesium Sulfate
|
Phase 2/Phase 3 |