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Cataract clinical trials

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NCT ID: NCT05853978 Recruiting - Cataract Clinical Trials

The Evaluation of Balanced Salt Solution During Cataract Surgery

Start date: May 2023
Phase: Phase 4
Study type: Interventional

This study aims to identify if the use of BSS PLUS® Sterile Intraocular Irrigating Solution as an irrigation solution leads to improved corneal outcomes vs BSS® Sterile Irrigating Solution in more compromised corneas.

NCT ID: NCT05832749 Recruiting - Bilateral Cataract Clinical Trials

Comparison of the Safety and Efficacy of Ophtesis Bio 3% With a Similar 3% Sodium Hyaluronate OVD

Start date: August 23, 2022
Phase:
Study type: Observational

Prospective, randomized, subject/evaluator-masked post market clinical study at up to 2 sites at Gemini eye clinic in Czech Republic. Randomization will be done by the eye surgeon. The purpose of this post market clinical trial is to compare the safety and efficacy of Ophtesis Bio 3% with a similar 3% sodium hyaluronate OVD in routine cataract surgery.

NCT ID: NCT05827133 Recruiting - Cataract Clinical Trials

Effect of Intraocular Lens (IOL) Centration and Tilt on Visual Performance With Clareon® Vivity® IOL Implantation

Start date: July 10, 2023
Phase:
Study type: Observational

The goal of this observational study is to assess the effect of intraocular lens (IOL) movement in patients who have undergone Clareon® Vivity® IOL implantation. The main question it aims to answer is: Does an association exist between IOL movement and patient quality of vision? Participants implanted with Clareon® Vivity® and Vivity® Toric IOLs will be asked to do the following: - consent to participate in the study - allow researchers to access their personal medical records - undergo a series of tests to assess the position of their IOLs and quality of vision Researchers will compare the patients' preoperative and postoperative test results to determine whether an association exists between IOL movement and patient quality of vision.

NCT ID: NCT05826353 Recruiting - Clinical trials for Fuchs Endothelial Corneal Dystrophy

A Study to Investigate the Safety and Efficacy of K-321 Eye Drops After Simultaneous Cataract Surgery and Descemetorhexis in Participants With Fuchs Endothelial Corneal Dystrophy (FECD)

Start date: May 11, 2023
Phase: Phase 3
Study type: Interventional

A study to assess the safety and efficacy of K-321 in participants with FECD after simultaneous cataract surgery and descemetorhexis.

NCT ID: NCT05822089 Recruiting - Clinical trials for Age Related Cataracts

Intraindividual Comparison of EMO IOLs

EMO
Start date: December 13, 2021
Phase: N/A
Study type: Interventional

The investigational devices are approved intraocular lenses (IOLs) intended to be implanted after phacoemulsification in individuals suffering from age-related cataract with the need of cataract surgery. Cataract surgery with precedent bilateral randomized IOL implantation will be performed in subjects who have signed an informed consent form. Postoperative examinations will be implemented in accordance with the approved investigational plan.

NCT ID: NCT05802550 Recruiting - Clinical trials for Age-related Cataract

Metabo-lipidomics of the Ocular Surface for Cataract Surgery

CATARACTOMIQUE
Start date: September 4, 2023
Phase: N/A
Study type: Interventional

Cataract is the world's leading cause of blindness, the treatment of which, exclusively surgical, offers excellent results in terms of visual recovery. It represents the most frequently performed surgery in France with more than 800,000 procedures each year. However, some patients develop postoperative ocular surface disease that can affect final visual acuity and quality of life. For example, dry eye disease, very common in the elderly, can be worsened by cataract surgery. The identification of ocular surface biomarkers predictive of the postoperative risk of ocular surface disease carries the promise of better personalized perioperative care. Conjunctival impression cytology represents a rapid, minimally invasive method of collecting conjunctival cells, which has proven its usefulness in the evaluation of diseases of the ocular surface. The aqueous humor is directly accessible at the beginning of the surgery. An approach combining ultra-high performance liquid chromatography coupled with high-resolution mass spectrometry on the cells of the ocular surface and on the aqueous humor could improve our understanding of the physiopathology of ocular surface disease following cataract surgery. This study will aim to 1) search for prognostic biomarkers of ocular surface disease after cataract surgery using a metabo-lipidomic approach 2) improve our understanding of the pathophysiological mechanisms involved.

NCT ID: NCT05797298 Recruiting - Visual Quality Clinical Trials

Toric Intraocular Lens (IOL) Implantation for Management of Cataracts

Start date: June 1, 2019
Phase:
Study type: Observational

This study included cataract patients who underwent toric intraocular lens (IOL) implantation, which aimed to evaluate the stability and clinical visual quality of toric IOLs.

NCT ID: NCT05779319 Recruiting - Cataract Clinical Trials

1000 Eyes Lens Biometry Study: Artificial Intelligence for Intraocular Lens Power Calculation

Start date: February 1, 2022
Phase:
Study type: Observational

The main purpose of the study is to develop an AI approach to improve intraocular lens power calculations.

NCT ID: NCT05776095 Recruiting - Clinical trials for Lens Implantation, Intraocular

Evaluation of Safety and Performance Outcomes of Eyedeal IOL Implantation After Cataract Removal

Start date: November 10, 2023
Phase: N/A
Study type: Interventional

A cataract is the clouding of the natural lens in the eye and is very common as when getting older. A cloudy lens makes it difficult to see. A cataract is treated by removing the cloudy lens and replacing it with an intraocular lens (known as an IOL). The goal of this clinical trial is to determine if the Eyedeal® IOL can be safely implanted in a subject's eye and if it can replace efficiently the natural lens. Subjects will be asked to attend a total of seven visits for this study for a period of 12 months after surgery.

NCT ID: NCT05754437 Recruiting - Dry Eye Clinical Trials

Efficacy of Low-Level Light Therapy in Reducing Dry Eye in Patients Undergoing Cataract Surgery

Start date: March 30, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to evaluate the effectiveness of Low Level Light Therapy (LLLT) in reducing the incidence or alleviating the severity of DED due to meibomian gland dysfunction in otherwise healthy patients undergoing cataract surgery. Participants will be randomly assigned in a 1:1 ratio to either a treatment group or a control group. The treatment group will receive LLLT one week before and one week after cataract surgery; the control group will not recieve LLLT at any time. Researchers will compare the treatment and the control group to see if patients receiving LLLT present with reduced signs and symptoms of ocular surface dysfunction with respect to the control group.